| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ciclopirox perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ciclopirox_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.264953 |
| VIM | vimentin | 0.111616 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0766671 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0761315 |
| CD44 | CD44 molecule (Indian blood group) | 0.0755082 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0633505 |
| LDHA | lactate dehydrogenase A | 0.0625445 |
| LMO7 | LIM domain 7 | 0.0601883 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0600491 |
| MT2A | metallothionein 2A | 0.0598609 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0567286 |
| PTMA | prothymosin, alpha | 0.0550714 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0528531 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0516949 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0500892 |
| B2M | beta-2-microglobulin | 0.0486565 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0485027 |
| HDAC9 | histone deacetylase 9 | 0.0461023 |
| H3-3B | H3.3 histone B | 0.0443716 |
| TPX2 | TPX2, microtubule-associated | 0.0433762 |
| FMNL2 | formin-like 2 | 0.0425286 |
| NAV2 | neuron navigator 2 | 0.042138 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0407116 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0404547 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.040164 |
| TAOK3 | TAO kinase 3 | 0.0397759 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0396356 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0394092 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0390602 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0376107 |
| PHF14 | PHD finger protein 14 | 0.0368176 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0366814 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0360954 |
| TMSB10 | thymosin beta 10 | 0.0360487 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0359742 |
| PCNX1 | pecanex 1 | 0.0357736 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0355417 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.0355291 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0351142 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0350743 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0350472 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.034578 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.034484 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0342349 |
| RIGI | RNA sensor RIG-I | 0.0338444 |
| RBM39 | RNA binding motif protein 39 | 0.0336312 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0335511 |
| BBX | bobby sox homolog (Drosophila) | 0.0332652 |
| RPL15 | ribosomal protein L15 | 0.0332607 |
| DNER | delta/notch-like EGF repeat containing | 0.0329694 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0324369 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0322267 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0321564 |
| ATXN1 | ataxin 1 | 0.032057 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0318714 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.031312 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0306055 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0304238 |
| CENPF | centromere protein F, 350/400kDa | 0.0302559 |
| CEP57 | centrosomal protein 57kDa | 0.0301255 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0298306 |
| EFNA5 | ephrin-A5 | 0.0297377 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.029662 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0296305 |
| SLMAP | sarcolemma associated protein | 0.0295651 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0294231 |
| R3HDM1 | R3H domain containing 1 | 0.0293353 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0292664 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0292272 |
| KIF5B | kinesin family member 5B | 0.0291431 |
| ATRN | attractin | 0.0291138 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.028837 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0286979 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.0284553 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0284177 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0283677 |
| SATB2 | SATB homeobox 2 | 0.0283316 |
| ANLN | anillin, actin binding protein | 0.0282977 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0281098 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0281009 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0280292 |
| OXSR1 | oxidative stress responsive 1 | 0.0278874 |
| RPS25 | ribosomal protein S25 | 0.0278473 |
| DEK | DEK proto-oncogene | 0.0273758 |
| RPS12 | ribosomal protein S12 | 0.0272457 |
| DIAPH1 | diaphanous-related formin 1 | 0.0270088 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0269908 |
| CENPE | centromere protein E, 312kDa | 0.0268642 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0267145 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0266879 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0264697 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0264587 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0263585 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0260217 |
| PXDN | peroxidasin | 0.0257777 |
| S100A10 | S100 calcium binding protein A10 | 0.0257739 |
| RPL8 | ribosomal protein L8 | 0.0256845 |
| ATXN2 | ataxin 2 | 0.0256281 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0254277 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0253162 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.131884 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0544272 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0543312 |
| SNX14 | sorting nexin 14 | -0.0508523 |
| MYOF | myoferlin | -0.0498771 |
| PRR16 | proline rich 16 | -0.0471505 |
| AHNAK | AHNAK nucleoprotein | -0.0406034 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0378303 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0377857 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0375326 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0363895 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0359951 |
| FUS | FUS RNA binding protein | -0.0359515 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0355953 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0354149 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0351919 |
| INTS6 | integrator complex subunit 6 | -0.0349886 |
| ANO6 | anoctamin 6 | -0.0343594 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0335883 |
| DENND1A | DENN/MADD domain containing 1A | -0.0330736 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0321875 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0320421 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0314362 |
| EVI5 | ecotropic viral integration site 5 | -0.0308031 |
| PCED1B | PC-esterase domain containing 1B | -0.030334 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0300133 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0292204 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0291502 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.028613 |
| ZNF638 | zinc finger protein 638 | -0.028209 |
| PRELID2 | PRELI domain containing 2 | -0.0280901 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0270705 |
| AEBP2 | AE binding protein 2 | -0.026933 |
| RPL34 | ribosomal protein L34 | -0.0268965 |
| PLEK2 | pleckstrin 2 | -0.026874 |
| ABR | active BCR-related | -0.0265487 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0262414 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.026231 |
| FBXO11 | F-box protein 11 | -0.0255396 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0251793 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0249224 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0247293 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0242188 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0241702 |
| NUP98 | nucleoporin 98kDa | -0.0240376 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0240193 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0237729 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0237729 |
| GOLGA3 | golgin A3 | -0.0236958 |
| COLEC11 | collectin sub-family member 11 | -0.0235983 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0235784 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0235641 |
| MSN | moesin | -0.0235268 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0234472 |
| GPC5 | glypican 5 | -0.0233203 |
| TARS3 | threonyl-tRNA synthetase 3 | -0.023226 |
| GOLGA4 | golgin A4 | -0.0229395 |
| COL5A1 | collagen, type V, alpha 1 | -0.0224041 |
| NABP1 | nucleic acid binding protein 1 | -0.0223421 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0221133 |
| SEC24A | SEC24 family member A | -0.0219757 |
| SMIM44 | small integral membrane protein 44 | -0.0218975 |
| TPM4 | tropomyosin 4 | -0.0217614 |
| DTNB | dystrobrevin, beta | -0.0217046 |
| CLASP1 | cytoplasmic linker associated protein 1 | -0.0215436 |
| EGFR | epidermal growth factor receptor | -0.0213575 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0213358 |
| INSIG2 | insulin induced gene 2 | -0.0211932 |
| MFSD4B | major facilitator superfamily domain containing 4B | -0.0211157 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0210611 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0209195 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0208015 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0206842 |
| NRG1 | neuregulin 1 | -0.0206096 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | -0.0204804 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0203441 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0203423 |
| THBS1 | thrombospondin 1 | -0.0200912 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0200449 |
| SHTN1 | shootin 1 | -0.0199828 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0199325 |
| WDR36 | WD repeat domain 36 | -0.0199292 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0199044 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0196098 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0195342 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0194296 |
| CANX | calnexin | -0.0193035 |
| GLRX | glutaredoxin (thioltransferase) | -0.0192649 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0191984 |
| SYAP1 | synapse associated protein 1 | -0.0191262 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | -0.0189633 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0189572 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.0189515 |
| RAI14 | retinoic acid induced 14 | -0.0189419 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0188784 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0188225 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) | -0.018702 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0186861 |
| LDLR | low density lipoprotein receptor | -0.0186613 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0185528 |
