| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ciclopirox perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ciclopirox_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.150638 |
| HMGA2 | high mobility group AT-hook 2 | 0.133084 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0996838 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0778398 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0654751 |
| B2M | beta-2-microglobulin | 0.0636575 |
| NRP1 | neuropilin 1 | 0.0558387 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0554981 |
| CAB39 | calcium binding protein 39 | 0.0542358 |
| SEPTIN9 | septin 9 | 0.0515973 |
| TMEM156 | transmembrane protein 156 | 0.0496275 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0479941 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0465088 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0445555 |
| ASPH | aspartate beta-hydroxylase | 0.0440952 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0437591 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0424016 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0402099 |
| NDRG1 | N-myc downstream regulated 1 | 0.0393686 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0392881 |
| SMOX | spermine oxidase | 0.0391518 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.037268 |
| MT2A | metallothionein 2A | 0.0371924 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.036549 |
| GLIS3 | GLIS family zinc finger 3 | 0.0355251 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0345336 |
| OSMR | oncostatin M receptor | 0.0338195 |
| MCL1 | myeloid cell leukemia 1 | 0.0332412 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0329512 |
| EREG | epiregulin | 0.032721 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0319082 |
| SLTM | SAFB-like, transcription modulator | 0.0318331 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0314582 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0313354 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0310732 |
| ATP13A3 | ATPase type 13A3 | 0.0309825 |
| CDCP1 | CUB domain containing protein 1 | 0.0309554 |
| SMAD3 | SMAD family member 3 | 0.0308854 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0308786 |
| UBC | ubiquitin C | 0.0307089 |
| ETV1 | ets variant 1 | 0.0296109 |
| DUSP6 | dual specificity phosphatase 6 | 0.0295155 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0291437 |
| AOPEP | aminopeptidase O (putative) | 0.0288359 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0278776 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0270842 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0269811 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0264167 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0263965 |
| EGFR | epidermal growth factor receptor | 0.02624 |
| YBX3 | Y box binding protein 3 | 0.0254844 |
| FNDC3B | fibronectin type III domain containing 3B | 0.024764 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0247181 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0246349 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0243312 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0240607 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0234863 |
| TOP1 | topoisomerase (DNA) I | 0.0231909 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0231753 |
| AREG | amphiregulin | 0.0224012 |
| EFNA5 | ephrin-A5 | 0.0223243 |
| ATP9A | ATPase, class II, type 9A | 0.0221159 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0218306 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0218117 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0214728 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0214228 |
| AHR | aryl hydrocarbon receptor | 0.0214205 |
| RPL37 | ribosomal protein L37 | 0.021407 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0209605 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0209402 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0209029 |
| ANGPTL4 | angiopoietin-like 4 | 0.0208326 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0208227 |
| APP | amyloid beta (A4) precursor protein | 0.0207501 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0207169 |
| RPS12 | ribosomal protein S12 | 0.0206855 |
| SVIL | supervillin | 0.0206811 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.020641 |
| ITGB5 | integrin, beta 5 | 0.0204689 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0200903 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0200852 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0200435 |
| DENND5B | DENN/MADD domain containing 5B | 0.0200152 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0197901 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0196925 |
| TPI1 | triosephosphate isomerase 1 | 0.0196007 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.019589 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.019528 |
| SLK | STE20-like kinase | 0.0192067 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0190904 |
| PDE8A | phosphodiesterase 8A | 0.0187966 |
| CTBP2 | C-terminal binding protein 2 | 0.0187518 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0183508 |
| IL6ST | interleukin 6 signal transducer | 0.0180559 |
| ENAH | enabled homolog (Drosophila) | 0.0180537 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0178953 |
| MTSS1 | metastasis suppressor 1 | 0.0177852 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0176582 |
| PTK2 | protein tyrosine kinase 2 | 0.0176441 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0176351 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.166378 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.141495 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.136946 |
| PTMA | prothymosin, alpha | -0.132809 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.111544 |
| TMSB10 | thymosin beta 10 | -0.104412 |
| FN1 | fibronectin 1 | -0.101493 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0870653 |
| SQSTM1 | sequestosome 1 | -0.0838926 |
| CANX | calnexin | -0.0720953 |
| VCL | vinculin | -0.0666288 |
| POTEF | POTE ankyrin domain family, member F | -0.0603887 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0563867 |
| RPL35A | ribosomal protein L35a | -0.0534544 |
| EGR1 | early growth response 1 | -0.0480446 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0443583 |
| GNAS | GNAS complex locus | -0.0427232 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.040826 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0401463 |
| RPLP1 | ribosomal protein, large, P1 | -0.0400781 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0382599 |
| S100A6 | S100 calcium binding protein A6 | -0.037437 |
| IER3 | immediate early response 3 | -0.0372497 |
| ENO1 | enolase 1, (alpha) | -0.036797 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0361734 |
| TMEM263 | transmembrane protein 263 | -0.0352888 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0338382 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0333704 |
| TMSB4X | thymosin beta 4, X-linked | -0.0328185 |
| HDLBP | high density lipoprotein binding protein | -0.0324303 |
| NRG1 | neuregulin 1 | -0.0316586 |
| AHNAK | AHNAK nucleoprotein | -0.0315683 |
| ACTG1 | actin gamma 1 | -0.0312662 |
| CENPF | centromere protein F, 350/400kDa | -0.0306347 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0302382 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0299454 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0295036 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0290969 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.028957 |
| SYT1 | synaptotagmin I | -0.0288736 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0288116 |
| ATF6 | activating transcription factor 6 | -0.0285083 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0283065 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0281739 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0279473 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0277879 |
| SEPTIN7 | septin 7 | -0.0275545 |
| CADM1 | cell adhesion molecule 1 | -0.027547 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0275152 |
| YBX1 | Y box binding protein 1 | -0.0271929 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0270427 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0267127 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0264686 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0253837 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0246815 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0243898 |
| RPL38 | ribosomal protein L38 | -0.0242355 |
| AEBP2 | AE binding protein 2 | -0.0239721 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0239326 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0239282 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0237807 |
| PFN1 | profilin 1 | -0.0235749 |
| MKI67 | marker of proliferation Ki-67 | -0.0235748 |
| ZNF217 | zinc finger protein 217 | -0.0235103 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0231611 |
| SMYD3 | SET and MYND domain containing 3 | -0.0230732 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0229494 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0229235 |
| HELZ | helicase with zinc finger | -0.0228728 |
| VIM | vimentin | -0.0228619 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0226999 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0225113 |
| SEC24D | SEC24 family member D | -0.0225028 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0222765 |
| FBXO11 | F-box protein 11 | -0.0220906 |
| TPR | translocated promoter region, nuclear basket protein | -0.0217566 |
| MYOF | myoferlin | -0.0216146 |
| RBM39 | RNA binding motif protein 39 | -0.0216129 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0214053 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0213553 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0213174 |
| GOLGB1 | golgin B1 | -0.0212706 |
| GPATCH2L | G patch domain containing 2-like | -0.021262 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0212398 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0212366 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0209694 |
| PLIN2 | perilipin 2 | -0.0208628 |
| CALU | calumenin | -0.0206183 |
| RPL34 | ribosomal protein L34 | -0.0205192 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0203982 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0202713 |
| HMGB1 | high mobility group box 1 | -0.0202436 |
| TMEM123 | transmembrane protein 123 | -0.0201279 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0199604 |
| RPS8 | ribosomal protein S8 | -0.0196803 |
| WDR45B | WD repeat domain 45B | -0.0195302 |
| ARF4 | ADP-ribosylation factor 4 | -0.0194167 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0194137 |
| SPAG9 | sperm associated antigen 9 | -0.0192827 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0192696 |
