| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cilostazol perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cilostazol_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ANXA1 | annexin A1 | 0.0563123 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0489589 |
| AREG | amphiregulin | 0.0464027 |
| MKI67 | marker of proliferation Ki-67 | 0.0451292 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0417255 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0398558 |
| MATR3 | matrin 3 | 0.039697 |
| YBX3 | Y box binding protein 3 | 0.0379065 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0378082 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0377858 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0373607 |
| TMEM41B | transmembrane protein 41B | 0.0372057 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.036958 |
| KIF18B | kinesin family member 18B | 0.035167 |
| KIF5B | kinesin family member 5B | 0.0347732 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0335848 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0325855 |
| RPS21 | ribosomal protein S21 | 0.0322107 |
| KLF6 | Kruppel-like factor 6 | 0.032159 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0320178 |
| ECT2 | epithelial cell transforming 2 | 0.0318923 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0316467 |
| WDR43 | WD repeat domain 43 | 0.0314759 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0311513 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0299246 |
| EDN1 | endothelin 1 | 0.0297786 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0296885 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0294973 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0282426 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0282211 |
| RBM25 | RNA binding motif protein 25 | 0.0276634 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0274918 |
| PNN | pinin, desmosome associated protein | 0.0269817 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0269591 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0263297 |
| PRRC2C | proline-rich coiled-coil 2C | 0.026231 |
| ATP11A | ATPase, class VI, type 11A | 0.0259092 |
| FUS | FUS RNA binding protein | 0.0256881 |
| RPS3 | ribosomal protein S3 | 0.0255 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0246979 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0245123 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0241704 |
| PRKCI | protein kinase C, iota | 0.0236711 |
| H1-0 | H1.0 linker histone | 0.0236344 |
| TPR | translocated promoter region, nuclear basket protein | 0.0230194 |
| OGA | O-GlcNAcase | 0.02274 |
| RPL26 | ribosomal protein L26 | 0.0223722 |
| RPL36 | ribosomal protein L36 | 0.0221484 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0219795 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.021902 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0211704 |
| THOC1 | THO complex 1 | 0.0210055 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0209993 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0208226 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0207153 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0206503 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0204902 |
| MIS18BP1 | MIS18 binding protein 1 | 0.020478 |
| ZFR | zinc finger RNA binding protein | 0.0203985 |
| NEK7 | NIMA-related kinase 7 | 0.0203565 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0201751 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0200734 |
| ARRDC3 | arrestin domain containing 3 | 0.0194993 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0192351 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0191999 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0188447 |
| STIL | SCL/TAL1 interrupting locus | 0.0187012 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0184309 |
| CDCA2 | cell division cycle associated 2 | 0.0182373 |
| KLHL24 | kelch-like family member 24 | 0.0182271 |
| RBM27 | RNA binding motif protein 27 | 0.0182015 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0181526 |
| NDC80 | NDC80 kinetochore complex component | 0.0180211 |
| RBM39 | RNA binding motif protein 39 | 0.0177311 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0175155 |
| HMGB2 | high mobility group box 2 | 0.0174607 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0174541 |
| RPL18 | ribosomal protein L18 | 0.0173392 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0173312 |
| CENPF | centromere protein F, 350/400kDa | 0.0171701 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0170751 |
| PCM1 | pericentriolar material 1 | 0.0170647 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0169332 |
| CEP192 | centrosomal protein 192kDa | 0.0168565 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0167864 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.0167195 |
| MED13L | mediator complex subunit 13-like | 0.0166218 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | 0.0166128 |
| AFDN | afadin, adherens junction formation factor | 0.0165656 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0165133 |
| CEP70 | centrosomal protein 70kDa | 0.0163981 |
| CIP2A | cellular inhibitor of PP2A | 0.0163661 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0162663 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0159413 |
| RTN4 | reticulon 4 | 0.0158878 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0157599 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0156627 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0153246 |
| THOC2 | THO complex 2 | 0.0153207 |
| CENPE | centromere protein E, 312kDa | 0.0153187 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.359933 |
| VIM | vimentin | -0.237134 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.216473 |
| HMGA2 | high mobility group AT-hook 2 | -0.168892 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.163429 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.137425 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.109491 |
| NLGN1 | neuroligin 1 | -0.0940303 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0922714 |
| EHBP1 | EH domain binding protein 1 | -0.0915544 |
| MMP12 | matrix metallopeptidase 12 | -0.0892662 |
| EGR1 | early growth response 1 | -0.0865485 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0832885 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0794563 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0714813 |
| ADIPOR2 | adiponectin receptor 2 | -0.0701459 |
| ASPH | aspartate beta-hydroxylase | -0.0694468 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0679456 |
| INTS6 | integrator complex subunit 6 | -0.062218 |
| POTEF | POTE ankyrin domain family, member F | -0.0618569 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0617665 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0617651 |
| CANX | calnexin | -0.0608331 |
| ACTG1 | actin gamma 1 | -0.0581881 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0559913 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0540951 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0540033 |
| TUBA1B | tubulin, alpha 1b | -0.0527449 |
| PTMA | prothymosin, alpha | -0.0510778 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0505446 |
| YAP1 | Yes-associated protein 1 | -0.0505135 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.049982 |
| PCDH7 | protocadherin 7 | -0.0478676 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0472791 |
| TENM3 | teneurin transmembrane protein 3 | -0.0469288 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0465853 |
| BCHE | butyrylcholinesterase | -0.0454468 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0452966 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0446977 |
| NHSL1 | NHS-like 1 | -0.0437897 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0433045 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0419999 |
| LRRC23 | leucine rich repeat containing 23 | -0.0419871 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0407414 |
| HMGA1 | high mobility group AT-hook 1 | -0.0397846 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0396848 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0388842 |
| GCG | glucagon | -0.0382546 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0378716 |
| RPS13 | ribosomal protein S13 | -0.0376332 |
| RPL35A | ribosomal protein L35a | -0.0367436 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0365642 |
| MGAT4C | MGAT4 family, member C | -0.0361327 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.036075 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0360511 |
| VDAC1 | voltage-dependent anion channel 1 | -0.035812 |
| RPS8 | ribosomal protein S8 | -0.0357603 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0356612 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0356106 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.034614 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0341858 |
| CUX1 | cut-like homeobox 1 | -0.0341703 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0340602 |
| IPO7 | importin 7 | -0.0339077 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0336144 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0334379 |
| RPS23 | ribosomal protein S23 | -0.0330779 |
| TPM4 | tropomyosin 4 | -0.0330653 |
| ZNF804A | zinc finger protein 804A | -0.0328701 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0325894 |
| ENO1 | enolase 1, (alpha) | -0.0324377 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0311779 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0311417 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.031103 |
| GOLGB1 | golgin B1 | -0.0308914 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.030257 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0299903 |
| HDAC9 | histone deacetylase 9 | -0.0299242 |
| ZNF638 | zinc finger protein 638 | -0.0298898 |
| LDHB | lactate dehydrogenase B | -0.0298358 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0298072 |
| PCDH9 | protocadherin 9 | -0.0297116 |
| BPTF | bromodomain PHD finger transcription factor | -0.0294605 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0294129 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0293933 |
| CALR | calreticulin | -0.029218 |
| CCND1 | cyclin D1 | -0.028699 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0285774 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0284837 |
| S100A10 | S100 calcium binding protein A10 | -0.0284819 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0277392 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0276196 |
| RTN3 | reticulon 3 | -0.0273107 |
| RHOA | ras homolog family member A | -0.0272506 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0266511 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0265957 |
| TBCA | tubulin folding cofactor A | -0.0264981 |
| SETX | senataxin | -0.026365 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0263162 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0259944 |
