| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cilostazol perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cilostazol_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.28034 |
| VEGFA | vascular endothelial growth factor A | 0.0749547 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0289835 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0284887 |
| TF | transferrin | 0.0250892 |
| RPS3 | ribosomal protein S3 | 0.021113 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.020309 |
| RPL23 | ribosomal protein L23 | 0.0180318 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0178608 |
| TNS1 | tensin 1 | 0.0176653 |
| RPL37A | ribosomal protein L37a | 0.0171939 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.01634 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0153452 |
| ORM1 | orosomucoid 1 | 0.0144843 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0142141 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0136969 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0135739 |
| RPS18 | ribosomal protein S18 | 0.0131807 |
| COL7A1 | collagen, type VII, alpha 1 | 0.012866 |
| DTNA | dystrobrevin, alpha | 0.0124236 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0119513 |
| RPS21 | ribosomal protein S21 | 0.0116259 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0109371 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0105589 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0103877 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0102879 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0101457 |
| PRELID2 | PRELI domain containing 2 | 0.0099768 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.00954572 |
| RPL31 | ribosomal protein L31 | 0.00947884 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.00946997 |
| USP47 | ubiquitin specific peptidase 47 | 0.00917985 |
| OPTN | optineurin | 0.00915741 |
| ICAM1 | intercellular adhesion molecule 1 | 0.00881245 |
| RPS7 | ribosomal protein S7 | 0.00880232 |
| RPS17 | ribosomal protein S17 | 0.00856589 |
| MT1G | metallothionein 1G | 0.00852789 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.00839521 |
| KRT18 | keratin 18, type I | 0.0083908 |
| HLF | hepatic leukemia factor | 0.00820018 |
| UBAP2L | ubiquitin associated protein 2-like | 0.00810141 |
| SSR1 | signal sequence receptor, alpha | 0.0080785 |
| RPL7A | ribosomal protein L7a | 0.00792503 |
| EWSR1 | EWS RNA-binding protein 1 | 0.00786722 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.00785555 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00785145 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.00780524 |
| TFF1 | trefoil factor 1 | 0.00769645 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0075729 |
| RPL9 | ribosomal protein L9 | 0.00745408 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.00731442 |
| RPS12 | ribosomal protein S12 | 0.00717651 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.00717396 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00705558 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.00697671 |
| FHIT | fragile histidine triad | 0.00696773 |
| PLEC | plectin | 0.00684929 |
| RPL38 | ribosomal protein L38 | 0.00684562 |
| JAG1 | jagged 1 | 0.00679029 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.00670919 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.00663582 |
| ARRDC3 | arrestin domain containing 3 | 0.00662334 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | 0.00655114 |
| PTPRH | protein tyrosine phosphatase, receptor type, H | 0.00654834 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00653634 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00653102 |
| SMTN | smoothelin | 0.00652679 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00652507 |
| CST3 | cystatin C | 0.00646741 |
| ABI1 | abl-interactor 1 | 0.00637188 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.00636053 |
| FURIN | furin (paired basic amino acid cleaving enzyme) | 0.00626719 |
| PRKCZ | protein kinase C, zeta | 0.00624434 |
| PGM3 | phosphoglucomutase 3 | 0.00623987 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00621667 |
| PNN | pinin, desmosome associated protein | 0.00620562 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.00619903 |
| HNMT | histamine N-methyltransferase | 0.00614512 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | 0.00614011 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.00613436 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.00609702 |
| RPS15A | ribosomal protein S15a | 0.00606348 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.00605023 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.00604669 |
| DNMBP | dynamin binding protein | 0.00603288 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 | 0.0060327 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) | 0.00599059 |
| RPS15 | ribosomal protein S15 | 0.00599052 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.00597837 |
| AFDN | afadin, adherens junction formation factor | 0.00595796 |
| OGFOD1 | 2-oxoglutarate and iron-dependent oxygenase domain containing 1 | 0.00594726 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.00594039 |
| APMAP | adipocyte plasma membrane associated protein | 0.00587669 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.00587434 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.00579661 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.00577045 |
| HLA-C | major histocompatibility complex, class I, C | 0.00576684 |
| PRELID1 | PRELI domain containing 1 | 0.00575243 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.00573027 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0057269 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.268921 |
| FN1 | fibronectin 1 | -0.116541 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0996037 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0784826 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0738956 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0737102 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0662093 |
| EHBP1 | EH domain binding protein 1 | -0.0650423 |
| DSPP | dentin sialophosphoprotein | -0.0554887 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0537487 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0531183 |
| GPC3 | glypican 3 | -0.0513312 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.041984 |
| VCL | vinculin | -0.0416355 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0401173 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0393919 |
| GPC6 | glypican 6 | -0.0392217 |
| ENO1 | enolase 1, (alpha) | -0.0388643 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0376429 |
| JMJD1C | jumonji domain containing 1C | -0.0365128 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0364202 |
| PEG3 | paternally expressed 3 | -0.0329668 |
| DST | dystonin | -0.032296 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0312758 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0312558 |
| EGR1 | early growth response 1 | -0.031185 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0309977 |
| TMEM123 | transmembrane protein 123 | -0.0292495 |
| FAM107B | family with sequence similarity 107, member B | -0.0292015 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0285637 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0281505 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0280487 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0273984 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.027053 |
| AHSG | alpha-2-HS-glycoprotein | -0.0268852 |
| PERP | PERP, TP53 apoptosis effector | -0.0266323 |
| PTCHD4 | patched domain containing 4 | -0.0264636 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0259914 |
| GK | glycerol kinase | -0.0258809 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0258189 |
| FTL | ferritin, light polypeptide | -0.0251611 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0246073 |
| ZNF644 | zinc finger protein 644 | -0.024524 |
| PCBP2 | poly(rC) binding protein 2 | -0.0244389 |
| CP | ceruloplasmin (ferroxidase) | -0.0242361 |
| SDC4 | syndecan 4 | -0.0238413 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0237616 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.023461 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.023245 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0229317 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0229099 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0226845 |
| RPLP1 | ribosomal protein, large, P1 | -0.0226583 |
| USP34 | ubiquitin specific peptidase 34 | -0.0224995 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0224633 |
| SEPTIN9 | septin 9 | -0.0222223 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0221878 |
| RPL11 | ribosomal protein L11 | -0.021825 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0216561 |
| ATXN1 | ataxin 1 | -0.0213864 |
| RUNX1 | runt-related transcription factor 1 | -0.0213815 |
| PARD3 | par-3 family cell polarity regulator | -0.0210416 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0208481 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0208368 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0207332 |
| RPLP0 | ribosomal protein, large, P0 | -0.0206831 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0206698 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0203515 |
| RPS24 | ribosomal protein S24 | -0.0202462 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0201275 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0201128 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0200369 |
| ITGA1 | integrin, alpha 1 | -0.0199926 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0194789 |
| RPS8 | ribosomal protein S8 | -0.0192964 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0191577 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0191044 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.018939 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0188475 |
| WDR45B | WD repeat domain 45B | -0.0186642 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0186107 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.018504 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0184652 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0182856 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0180171 |
| APOB | apolipoprotein B | -0.0179583 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0179297 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0179252 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0178538 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.01783 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.01782 |
| PKP4 | plakophilin 4 | -0.0176862 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0176573 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0174718 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.017373 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0173193 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | -0.0172837 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0172367 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0171888 |
| AHNAK | AHNAK nucleoprotein | -0.0171026 |
