Cilostazol_Hs 766T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Cilostazol perturbation in Hs 766T cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Cilostazol_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
MSN moesin 0.10424
PODXL podocalyxin-like 0.0992732
B2M beta-2-microglobulin 0.0838666
POTEF POTE ankyrin domain family, member F 0.078699
HLA-B major histocompatibility complex, class I, B 0.0756706
MT2A metallothionein 2A 0.0733378
RPS21 ribosomal protein S21 0.0673275
RPS3 ribosomal protein S3 0.0648657
PCDH1 protocadherin 1 0.0603649
FOSL1 FOS-like antigen 1 0.0573699
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.0565052
LAMA5 laminin, alpha 5 0.0542547
KRT6A keratin 6A, type II 0.053703
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0516815
SLC35F3 solute carrier family 35, member F3 0.0515669
IGF2 insulin-like growth factor 2 0.0511945
RPS6 ribosomal protein S6 0.0493251
RPS12 ribosomal protein S12 0.0490201
RPL37A ribosomal protein L37a 0.0481798
VEGFA vascular endothelial growth factor A 0.0470695
RPS8 ribosomal protein S8 0.0459471
LDHA lactate dehydrogenase A 0.0450041
TIMP3 TIMP metallopeptidase inhibitor 3 0.0431287
MYH9 myosin, heavy chain 9, non-muscle 0.0429764
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.041063
RPL9 ribosomal protein L9 0.0405325
PLEC plectin 0.0400083
CALB1 calbindin 1, 28kDa 0.0396609
IFI6 interferon, alpha-inducible protein 6 0.0394359
HSPG2 heparan sulfate proteoglycan 2 0.0387821
RPLP2 ribosomal protein, large, P2 0.0384181
SRRM2 serine/arginine repetitive matrix 2 0.0383823
CYB5R3 cytochrome b5 reductase 3 0.0380095
IFI27 interferon, alpha-inducible protein 27 0.0372015
IFITM1 interferon induced transmembrane protein 1 0.0371416
RPS19 ribosomal protein S19 0.036927
CLU clusterin 0.0358021
TINAGL1 tubulointerstitial nephritis antigen-like 1 0.0357359
ITGA6 integrin, alpha 6 0.0355638
EEF2 eukaryotic translation elongation factor 2 0.0351957
RPL23 ribosomal protein L23 0.0345798
EFHD2 EF-hand domain family, member D2 0.0344483
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.0337591
RPL21 ribosomal protein L21 0.033459
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.0333416
RPS13 ribosomal protein S13 0.0327432
TPM3 tropomyosin 3 0.0324458
CST3 cystatin C 0.0322819
APLP2 amyloid beta (A4) precursor-like protein 2 0.0319269
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 0.0319102
S100A11 S100 calcium binding protein A11 0.031881
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.031403
IFITM3 interferon induced transmembrane protein 3 0.0313938
BCAR3 breast cancer anti-estrogen resistance 3 0.0311746
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0311309
LAMC2 laminin, gamma 2 0.0308877
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.030846
PFN1 profilin 1 0.0293767
EGR1 early growth response 1 0.0289697
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.0288819
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0285898
NECTIN1 nectin cell adhesion molecule 1 0.0284743
PALM2AKAP2 PALM2 and AKAP2 fusion 0.028138
PRRC2C proline-rich coiled-coil 2C 0.0279751
TGM2 transglutaminase 2 0.0279415
TNS4 tensin 4 0.0273856
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.0271353
RPL11 ribosomal protein L11 0.0269148
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0266567
S100A9 S100 calcium binding protein A9 0.0266274
RPS17 ribosomal protein S17 0.0266178
SLK STE20-like kinase 0.0265653
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.0265148
NCOR2 nuclear receptor corepressor 2 0.0264281
IFI44L interferon-induced protein 44-like 0.0262708
TMSB10 thymosin beta 10 0.0259726
FXYD5 FXYD domain containing ion transport regulator 5 0.0259026
RPL36 ribosomal protein L36 0.0258578
ENO2 enolase 2 (gamma, neuronal) 0.0257796
ANGPTL4 angiopoietin-like 4 0.0253047
RPL31 ribosomal protein L31 0.0252765
ZMIZ1 zinc finger, MIZ-type containing 1 0.0252071
AMOTL1 angiomotin like 1 0.0248259
SET SET nuclear proto-oncogene 0.0246299
CD44 CD44 molecule (Indian blood group) 0.0245281
RPS14 ribosomal protein S14 0.0239727
LUZP1 leucine zipper protein 1 0.023897
MACF1 microtubule-actin crosslinking factor 1 0.0238049
EPHA2 EPH receptor A2 0.0237591
CDKN2A cyclin-dependent kinase inhibitor 2A 0.0232619
ISG15 ISG15 ubiquitin-like modifier 0.0232195
FTL ferritin, light polypeptide 0.0231255
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0230793
RPS29 ribosomal protein S29 0.0227947
ANO1 anoctamin 1, calcium activated chloride channel 0.0227348
UQCRB ubiquinol-cytochrome c reductase binding protein 0.0225904
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0224509
MDK midkine (neurite growth-promoting factor 2) 0.022329
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0216918
ACTN1 actinin, alpha 1 0.0212622

decreased expression

Symbol Name Standardized Value
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.167733
AHNAK AHNAK nucleoprotein -0.130101
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.127056
TRIO trio Rho guanine nucleotide exchange factor -0.0885909
MYOF myoferlin -0.0771003
CANX calnexin -0.0739327
EMP1 epithelial membrane protein 1 -0.0659621
ANXA1 annexin A1 -0.0655735
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0612285
RBM39 RNA binding motif protein 39 -0.0600812
KDM3A lysine (K)-specific demethylase 3A -0.0574256
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0549692
H1-0 H1.0 linker histone -0.0540159
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0535236
SEC31A SEC31 homolog A (S. cerevisiae) -0.052816
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0517399
LOC112694756 uncharaterized LOC112694756 -0.0503267
ITCH itchy E3 ubiquitin protein ligase -0.0484971
LMO7 LIM domain 7 -0.0482714
COPB1 coatomer protein complex, subunit beta 1 -0.0480508
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -0.0471818
EZR ezrin -0.0470706
OGA O-GlcNAcase -0.0456537
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 -0.0454514
MORF4L2 mortality factor 4 like 2 -0.045276
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0444559
MBNL2 muscleblind-like splicing regulator 2 -0.0439812
ANXA2 annexin A2 -0.042905
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0414436
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0395296
MARCHF6 membrane associated ring-CH-type finger 6 -0.0388961
RLF rearranged L-myc fusion -0.0388072
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0380867
ARID4B AT rich interactive domain 4B (RBP1-like) -0.037898
GNAS GNAS complex locus -0.037865
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.036439
DLG1 discs, large homolog 1 (Drosophila) -0.0357738
ARF1 ADP-ribosylation factor 1 -0.0355694
NPEPPS aminopeptidase puromycin sensitive -0.0347626
RAB1A RAB1A, member RAS oncogene family -0.0346977
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0339556
NRIP1 nuclear receptor interacting protein 1 -0.0336686
ESYT2 extended synaptotagmin-like protein 2 -0.0335191
HDLBP high density lipoprotein binding protein -0.0335022
LMAN1 lectin, mannose-binding, 1 -0.032584
SDCBP syndecan binding protein (syntenin) -0.032456
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0324391
SQLE squalene epoxidase -0.0318262
CAVIN1 caveolae associated protein 1 -0.0312811
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0307838
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0302074
HLA-E major histocompatibility complex, class I, E -0.0301626
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0301175
SPAG9 sperm associated antigen 9 -0.0295871
PRRC1 proline-rich coiled-coil 1 -0.0295496
ANKRD10 ankyrin repeat domain 10 -0.0294844
ANLN anillin, actin binding protein -0.0292705
BZW1 basic leucine zipper and W2 domains 1 -0.0290188
STAU1 staufen double-stranded RNA binding protein 1 -0.0288652
FN1 fibronectin 1 -0.0284559
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -0.0283134
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0282505
PALLD palladin, cytoskeletal associated protein -0.0280891
RAI14 retinoic acid induced 14 -0.0279472
IARS1 isoleucyl-tRNA synthetase 1 -0.0278753
RAB14 RAB14, member RAS oncogene family -0.027739
RTN3 reticulon 3 -0.0277031
NAMPT nicotinamide phosphoribosyltransferase -0.0277026
TRA2A transformer 2 alpha homolog (Drosophila) -0.0276268
QKI QKI, KH domain containing, RNA binding -0.0276234
SRP54 signal recognition particle 54kDa -0.0272093
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0270743
S100A10 S100 calcium binding protein A10 -0.0270579
MEF2A myocyte enhancer factor 2A -0.0268754
NCOA3 nuclear receptor coactivator 3 -0.02677
COPA coatomer protein complex, subunit alpha -0.0265212
TKT transketolase -0.0264757
ZMYM2 zinc finger, MYM-type 2 -0.0260408
RAB2A RAB2A, member RAS oncogene family -0.0260179
ANKRD33B ankyrin repeat domain 33B -0.0259994
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0254978
SUCO SUN domain containing ossification factor -0.0253207
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0252353
COG5 component of oligomeric golgi complex 5 -0.0249859
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0249402
PGK1 phosphoglycerate kinase 1 -0.0249108
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0249072
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0247424
FNDC3B fibronectin type III domain containing 3B -0.0245667
AFF4 AF4/FMR2 family, member 4 -0.024432
PIBF1 progesterone immunomodulatory binding factor 1 -0.0243161
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0242885
RAD21 RAD21 homolog (S. pombe) -0.024272
TXNRD1 thioredoxin reductase 1 -0.0240022
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.0238549
ZFR zinc finger RNA binding protein -0.0238298
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.0234908
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) -0.0232585
MBNL1 muscleblind-like splicing regulator 1 -0.0232129
ZEB1 zinc finger E-box binding homeobox 1 -0.0231777