| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cilostazol perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cilostazol_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.127721 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0911326 |
| PTMA | prothymosin, alpha | 0.0893622 |
| HLA-B | major histocompatibility complex, class I, B | 0.0779658 |
| TMSB4X | thymosin beta 4, X-linked | 0.0745564 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0662268 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0639182 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0600667 |
| EZR | ezrin | 0.0539068 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0518255 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0485283 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0479158 |
| MKI67 | marker of proliferation Ki-67 | 0.0475656 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0462083 |
| CAPRIN2 | caprin family member 2 | 0.0442277 |
| MT1X | metallothionein 1X | 0.042471 |
| MATR3 | matrin 3 | 0.0418826 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.040235 |
| RPL23 | ribosomal protein L23 | 0.0399303 |
| KLF6 | Kruppel-like factor 6 | 0.0387317 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0365182 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0365175 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0355727 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0344259 |
| ACTG1 | actin gamma 1 | 0.0330609 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0325155 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0312027 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0310966 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0307158 |
| TMEM41B | transmembrane protein 41B | 0.030613 |
| ARRDC3 | arrestin domain containing 3 | 0.0295587 |
| RPL26 | ribosomal protein L26 | 0.0291129 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0290705 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0290672 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.028635 |
| RPL35A | ribosomal protein L35a | 0.0285771 |
| HPCAL1 | hippocalcin-like 1 | 0.0284857 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0274438 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0273478 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0273356 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0272377 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.026562 |
| RTN4 | reticulon 4 | 0.0263579 |
| RBM25 | RNA binding motif protein 25 | 0.0261177 |
| RPS21 | ribosomal protein S21 | 0.0254909 |
| FUS | FUS RNA binding protein | 0.0251757 |
| RPS18 | ribosomal protein S18 | 0.0251303 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0251112 |
| RPS3 | ribosomal protein S3 | 0.024806 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0246093 |
| RRM2 | ribonucleotide reductase M2 | 0.02456 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0245077 |
| SQSTM1 | sequestosome 1 | 0.0243371 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0241158 |
| SRGN | serglycin | 0.0238699 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0235987 |
| RPL38 | ribosomal protein L38 | 0.0235737 |
| TMSB10 | thymosin beta 10 | 0.0234724 |
| YBX3 | Y box binding protein 3 | 0.0227125 |
| SPAG9 | sperm associated antigen 9 | 0.0226807 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0226005 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0225999 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0219218 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0217437 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0216577 |
| OGA | O-GlcNAcase | 0.021603 |
| PRRC2A | proline-rich coiled-coil 2A | 0.02153 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0212725 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0212179 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.021031 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0207689 |
| RBM39 | RNA binding motif protein 39 | 0.0207131 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0206323 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0204202 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0203199 |
| RPLP2 | ribosomal protein, large, P2 | 0.0201411 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0199615 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0197827 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0197414 |
| VEGFA | vascular endothelial growth factor A | 0.0196609 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0196161 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0195502 |
| ECT2 | epithelial cell transforming 2 | 0.0195393 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.019529 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0194873 |
| WDR43 | WD repeat domain 43 | 0.019447 |
| RACK1 | receptor for activated C kinase 1 | 0.0192647 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0191723 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0185661 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0185642 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.018444 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0184283 |
| PLEC | plectin | 0.0183707 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0182645 |
| RPL36A | ribosomal protein L36a | 0.0182288 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0180154 |
| RPL36 | ribosomal protein L36 | 0.0180109 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0179516 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0179352 |
| CAVIN1 | caveolae associated protein 1 | 0.0178807 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.155038 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.130168 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.129815 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.12671 |
| VIM | vimentin | -0.124278 |
| DST | dystonin | -0.122684 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.114805 |
| TP63 | tumor protein p63 | -0.112798 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.10987 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.103274 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.101127 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0904781 |
| EHBP1 | EH domain binding protein 1 | -0.0904104 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0867765 |
| POTEF | POTE ankyrin domain family, member F | -0.0836291 |
| CANX | calnexin | -0.0825563 |
| CADM2 | cell adhesion molecule 2 | -0.082089 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0788667 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0736696 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0730375 |
| EPHA4 | EPH receptor A4 | -0.0727964 |
| HDAC9 | histone deacetylase 9 | -0.0721172 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0716456 |
| EFNA5 | ephrin-A5 | -0.0708611 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0657919 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0626284 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0619502 |
| MYOF | myoferlin | -0.0597211 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0591227 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0566664 |
| CD44 | CD44 molecule (Indian blood group) | -0.054097 |
| RUNX1 | runt-related transcription factor 1 | -0.0536837 |
| EXOC4 | exocyst complex component 4 | -0.0529413 |
| TNS3 | tensin 3 | -0.0524827 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0520857 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0515951 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0508947 |
| EGFR | epidermal growth factor receptor | -0.0506937 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0494026 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0464409 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0459274 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0455844 |
| DNER | delta/notch-like EGF repeat containing | -0.0446696 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0430436 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.042734 |
| FMNL2 | formin-like 2 | -0.0423356 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0415605 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.040649 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0404405 |
| COL5A2 | collagen, type V, alpha 2 | -0.0399831 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0387245 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0386235 |
| TXNIP | thioredoxin interacting protein | -0.0374455 |
| LYST | lysosomal trafficking regulator | -0.0365862 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0363904 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0359471 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0359418 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0357603 |
| PLK2 | polo-like kinase 2 | -0.0356861 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0356201 |
| EGR1 | early growth response 1 | -0.0350117 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0348061 |
| NBEAL1 | neurobeachin-like 1 | -0.0347191 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.034614 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0345603 |
| TMEM123 | transmembrane protein 123 | -0.0342281 |
| BPTF | bromodomain PHD finger transcription factor | -0.0337271 |
| HMGA1 | high mobility group AT-hook 1 | -0.0336745 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0333916 |
| JMJD1C | jumonji domain containing 1C | -0.0332469 |
| SLC39A10 | solute carrier family 39 (zinc transporter), member 10 | -0.0330475 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0323249 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.030984 |
| PLIN2 | perilipin 2 | -0.0308516 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0306776 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0302976 |
| ZNF638 | zinc finger protein 638 | -0.0302633 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0299913 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0297148 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0295499 |
| INTS6 | integrator complex subunit 6 | -0.0295353 |
| TAOK1 | TAO kinase 1 | -0.0290784 |
| LMAN1 | lectin, mannose-binding, 1 | -0.029052 |
| TAPBP | TAP binding protein (tapasin) | -0.0283186 |
| DENND1A | DENN/MADD domain containing 1A | -0.0283064 |
| FNIP1 | folliculin interacting protein 1 | -0.0282405 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0282275 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0281459 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.027924 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0278045 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0277586 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0275078 |
| WDR27 | WD repeat domain 27 | -0.0274484 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0273191 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0269025 |
| GLG1 | golgi glycoprotein 1 | -0.0268482 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0268011 |
| CUX1 | cut-like homeobox 1 | -0.0267002 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0261257 |
| PKM | pyruvate kinase, muscle | -0.0261219 |
