Cilostazol_NCI-H1573 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Cilostazol perturbation in NCI-H1573 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Cilostazol_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.210851
RPS3 ribosomal protein S3 0.160007
TMSB10 thymosin beta 10 0.144583
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.117989
LDHA lactate dehydrogenase A 0.113674
PTMA prothymosin, alpha 0.107709
CST3 cystatin C 0.105882
FAM13A family with sequence similarity 13, member A 0.084647
PRRC2C proline-rich coiled-coil 2C 0.0806522
FTL ferritin, light polypeptide 0.0770884
ARRDC3 arrestin domain containing 3 0.072757
RPL37A ribosomal protein L37a 0.0709255
LAMB3 laminin, beta 3 0.0695376
ACTG1 actin gamma 1 0.068342
LAMC2 laminin, gamma 2 0.0683305
PKM pyruvate kinase, muscle 0.0671074
TPT1 tumor protein, translationally-controlled 1 0.0644162
RPS12 ribosomal protein S12 0.0611684
KRT18 keratin 18, type I 0.0581942
NDRG1 N-myc downstream regulated 1 0.0581853
MKI67 marker of proliferation Ki-67 0.0555041
VEGFA vascular endothelial growth factor A 0.0534976
H1-0 H1.0 linker histone 0.053213
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0496744
HLA-B major histocompatibility complex, class I, B 0.049301
FTH1 ferritin, heavy polypeptide 1 0.04743
S100A10 S100 calcium binding protein A10 0.0471732
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0456311
RPS17 ribosomal protein S17 0.04549
SRRM2 serine/arginine repetitive matrix 2 0.044766
BHLHE40 basic helix-loop-helix family, member e40 0.0447499
SEC61G Sec61 gamma subunit 0.0446415
CAV1 caveolin 1, caveolae protein, 22kDa 0.0444331
RACK1 receptor for activated C kinase 1 0.0430562
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0422472
STC1 stanniocalcin 1 0.0418886
RPL31 ribosomal protein L31 0.0416451
HOOK2 hook microtubule-tethering protein 2 0.0407341
EEF2 eukaryotic translation elongation factor 2 0.0405515
NGLY1 N-glycanase 1 0.0404029
PGK1 phosphoglycerate kinase 1 0.0395812
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.038949
PDIA6 protein disulfide isomerase family A, member 6 0.0388909
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0385982
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0382786
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.0374703
S100P S100 calcium binding protein P 0.0371217
HSPA8 heat shock 70kDa protein 8 0.036964
RPL34 ribosomal protein L34 0.0367586
ENO1 enolase 1, (alpha) 0.0365099
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0357769
DSPP dentin sialophosphoprotein 0.0354358
RPS6 ribosomal protein S6 0.0346875
RPL30 ribosomal protein L30 0.0343493
RPS8 ribosomal protein S8 0.0342705
RPL11 ribosomal protein L11 0.0333419
B2M beta-2-microglobulin 0.0330846
RPL7 ribosomal protein L7 0.0327161
ERRFI1 ERBB receptor feedback inhibitor 1 0.0325171
BZW1 basic leucine zipper and W2 domains 1 0.0324224
HILPDA hypoxia inducible lipid droplet-associated 0.0323613
DDIT4 DNA-damage-inducible transcript 4 0.0318438
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0313321
MXI1 MAX interactor 1, dimerization protein 0.0309196
S100A6 S100 calcium binding protein A6 0.0307822
SQSTM1 sequestosome 1 0.0306844
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0300082
CSTB cystatin B (stefin B) 0.0293686
KCMF1 potassium channel modulatory factor 1 0.0292035
SREBF2 sterol regulatory element binding transcription factor 2 0.0291672
RPS2 ribosomal protein S2 0.0288716
NAMPT nicotinamide phosphoribosyltransferase 0.0286105
CSDE1 cold shock domain containing E1, RNA-binding 0.0283991
RPS27A ribosomal protein S27a 0.0283701
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0283646
NACA nascent polypeptide-associated complex alpha subunit 0.0282705
PLEC plectin 0.0282578
RPL23 ribosomal protein L23 0.0281069
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.0278705
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase) 0.0271309
ANXA1 annexin A1 0.0269775
IFI6 interferon, alpha-inducible protein 6 0.0268742
HDLBP high density lipoprotein binding protein 0.0267594
MATR3 matrin 3 0.026581
RPL17-C18ORF32 RPL17-C18orf32 readthrough 0.0265524
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.0264375
EIF4B eukaryotic translation initiation factor 4B 0.0263704
RPL26 ribosomal protein L26 0.0263431
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.0260652
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0260299
RPS25 ribosomal protein S25 0.0258628
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.0256873
MYH9 myosin, heavy chain 9, non-muscle 0.0255893
CTTN cortactin 0.0255524
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0254868
EIF1 eukaryotic translation initiation factor 1 0.0253916
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.0252627
BRWD3 bromodomain and WD repeat domain containing 3 0.0247734
ZMYND8 zinc finger, MYND-type containing 8 0.0246562
RPS29 ribosomal protein S29 0.0244125

decreased expression

Symbol Name Standardized Value
THSD4 thrombospondin, type I, domain containing 4 -0.0837608
ASPH aspartate beta-hydroxylase -0.0675327
GRAMD1B GRAM domain containing 1B -0.0653655
MYOF myoferlin -0.0640749
JMJD1C jumonji domain containing 1C -0.0623159
TXNRD1 thioredoxin reductase 1 -0.0620181
NABP1 nucleic acid binding protein 1 -0.0612598
FNDC3B fibronectin type III domain containing 3B -0.0567815
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0556877
INTS6 integrator complex subunit 6 -0.0548535
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.053893
OSMR oncostatin M receptor -0.0538635
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0517134
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.046563
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0430782
PDLIM5 PDZ and LIM domain 5 -0.0430763
ZNF638 zinc finger protein 638 -0.0424479
MCTP1 multiple C2 domains, transmembrane 1 -0.042192
DOCK5 dedicator of cytokinesis 5 -0.0417584
PM20D1 peptidase M20 domain containing 1 -0.0415774
SMYD3 SET and MYND domain containing 3 -0.0414082
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0413449
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0406414
USP34 ubiquitin specific peptidase 34 -0.0403937
MCL1 myeloid cell leukemia 1 -0.0391793
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0373106
GPC6 glypican 6 -0.0371984
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0352547
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0343687
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0336336
LRP12 low density lipoprotein receptor-related protein 12 -0.033019
SAMD4A sterile alpha motif domain containing 4A -0.0330145
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.032971
PDE4D phosphodiesterase 4D, cAMP-specific -0.0326848
RIMS2 regulating synaptic membrane exocytosis 2 -0.0323892
VCL vinculin -0.0322756
EFNA5 ephrin-A5 -0.0319546
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0318573
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.0312095
VMP1 vacuole membrane protein 1 -0.0311099
ARB2A ARB2 cotranscriptional regulator A -0.0310215
RAD51B RAD51 paralog B -0.0300786
TSC22D2 TSC22 domain family, member 2 -0.0299223
CCNL1 cyclin L1 -0.0290973
DSCAM Down syndrome cell adhesion molecule -0.0287575
ZBTB20 zinc finger and BTB domain containing 20 -0.028736
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.028401
SUMF1 sulfatase modifying factor 1 -0.0277919
EXT1 exostosin glycosyltransferase 1 -0.0274536
LRP1B low density lipoprotein receptor-related protein 1B -0.0267154
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.0266518
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0259098
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.0244555
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0242835
KDM4C lysine (K)-specific demethylase 4C -0.0242774
PTK2 protein tyrosine kinase 2 -0.0240997
NCOA2 nuclear receptor coactivator 2 -0.024065
SOD2 superoxide dismutase 2, mitochondrial -0.024057
LGALS12 lectin, galactoside-binding, soluble, 12 -0.0239844
TAS2R14 taste receptor, type 2, member 14 -0.0238484
MAP7 microtubule-associated protein 7 -0.0234201
MAML3 mastermind-like 3 (Drosophila) -0.0232393
FAF1 Fas (TNFRSF6) associated factor 1 -0.023133
GPHN gephyrin -0.0230766
CCSER1 coiled-coil serine-rich protein 1 -0.0228513
ZC3H12B zinc finger CCCH-type containing 12B -0.0226744
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0224385
SHTN1 shootin 1 -0.0221895
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.021932
ERBIN erbb2 interacting protein -0.0218703
RTN4 reticulon 4 -0.0218118
DLG1 discs, large homolog 1 (Drosophila) -0.0216647
MBD5 methyl-CpG binding domain protein 5 -0.0216218
LOC112694756 uncharaterized LOC112694756 -0.0216192
TOP1 topoisomerase (DNA) I -0.0215718
FOXP1 forkhead box P1 -0.0215453
FNIP1 folliculin interacting protein 1 -0.0214612
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) -0.0213494
RABGAP1L RAB GTPase activating protein 1-like -0.0213201
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0210751
PTEN phosphatase and tensin homolog -0.0210109
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0208542
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -0.02072
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -0.0206623
CNOT1 CCR4-NOT transcription complex, subunit 1 -0.0206113
CCDC91 coiled-coil domain containing 91 -0.0204109
FBXO11 F-box protein 11 -0.0203451
SLTM SAFB-like, transcription modulator -0.0197938
BLZF1 basic leucine zipper nuclear factor 1 -0.0195164
NBAS neuroblastoma amplified sequence -0.0193369
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.0192541
FRYL FRY-like -0.0192393
PTPRD protein tyrosine phosphatase, receptor type, D -0.019192
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0191263
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.0191224
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0190175
ANKRD17 ankyrin repeat domain 17 -0.0188947
TBC1D5 TBC1 domain family, member 5 -0.0187927
DST dystonin -0.0187156
AEBP2 AE binding protein 2 -0.0185807