| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cilostazol perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cilostazol_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.129898 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0605842 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0547787 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0483924 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0473014 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.046059 |
| GRAMD1B | GRAM domain containing 1B | 0.0378235 |
| RPS3 | ribosomal protein S3 | 0.0358209 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0328911 |
| IGF2 | insulin-like growth factor 2 | 0.0306034 |
| MKI67 | marker of proliferation Ki-67 | 0.030507 |
| HDGF | hepatoma-derived growth factor | 0.0297116 |
| TPM3 | tropomyosin 3 | 0.0291882 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0268029 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0258537 |
| RPS12 | ribosomal protein S12 | 0.0257099 |
| WWOX | WW domain containing oxidoreductase | 0.0256419 |
| RPS18 | ribosomal protein S18 | 0.0238746 |
| RPS17 | ribosomal protein S17 | 0.0237752 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0199771 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0195273 |
| RPL3 | ribosomal protein L3 | 0.0193498 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.018865 |
| RPL9 | ribosomal protein L9 | 0.018699 |
| RPL37A | ribosomal protein L37a | 0.018469 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0176224 |
| PNN | pinin, desmosome associated protein | 0.0168805 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0165695 |
| RPL36 | ribosomal protein L36 | 0.0161224 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0160793 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0156671 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0156577 |
| MSN | moesin | 0.0155856 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0155589 |
| PFKP | phosphofructokinase, platelet | 0.0154292 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.0153416 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0149304 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0149005 |
| CENPF | centromere protein F, 350/400kDa | 0.0147305 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0143861 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0141469 |
| VEGFA | vascular endothelial growth factor A | 0.0139945 |
| RPS19 | ribosomal protein S19 | 0.0139864 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0138368 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0135641 |
| FAT1 | FAT atypical cadherin 1 | 0.0135316 |
| DNMBP | dynamin binding protein | 0.0134108 |
| TMEM14C | transmembrane protein 14C | 0.0133869 |
| SET | SET nuclear proto-oncogene | 0.0132601 |
| PLEC | plectin | 0.0132384 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0131058 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0128585 |
| FLNA | filamin A, alpha | 0.0128514 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0127964 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0127671 |
| IL6 | interleukin 6 | 0.0126043 |
| SMAD3 | SMAD family member 3 | 0.0124793 |
| TCP1 | t-complex 1 | 0.0123704 |
| RPS21 | ribosomal protein S21 | 0.0119854 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0119801 |
| SSR1 | signal sequence receptor, alpha | 0.0118899 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0117118 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0116853 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0116437 |
| CHMP7 | charged multivesicular body protein 7 | 0.0116166 |
| SPAG5 | sperm associated antigen 5 | 0.01158 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0115643 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0114425 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0114279 |
| OPTN | optineurin | 0.0114114 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0113149 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0109972 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0109911 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.010874 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | 0.0108363 |
| RPS29 | ribosomal protein S29 | 0.0107428 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0106145 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.0105942 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.010431 |
| CD44 | CD44 molecule (Indian blood group) | 0.0103691 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0103212 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0103195 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.0102534 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0100574 |
| SSRP1 | structure specific recognition protein 1 | 0.0100464 |
| CLU | clusterin | 0.00993055 |
| CBX3 | chromobox homolog 3 | 0.00975947 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.00973751 |
| NDUFS5 | NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) | 0.00971706 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.00969691 |
| GPX4 | glutathione peroxidase 4 | 0.00962519 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.00962187 |
| HJURP | Holliday junction recognition protein | 0.0095436 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.00953544 |
| RPS10 | ribosomal protein S10 | 0.00945865 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.00944329 |
| CST3 | cystatin C | 0.00943422 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00942344 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.00932845 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0093053 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.254601 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.177236 |
| FTL | ferritin, light polypeptide | -0.175703 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.12616 |
| VIM | vimentin | -0.114844 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.103611 |
| TXNRD1 | thioredoxin reductase 1 | -0.0996388 |
| TMSB10 | thymosin beta 10 | -0.0857855 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0854622 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0745026 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0737303 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0689532 |
| IER3 | immediate early response 3 | -0.068824 |
| S100A6 | S100 calcium binding protein A6 | -0.0681199 |
| PTK2 | protein tyrosine kinase 2 | -0.0672283 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0656344 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0574291 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0570605 |
| DSCAM | Down syndrome cell adhesion molecule | -0.055438 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0543762 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0543511 |
| ERBIN | erbb2 interacting protein | -0.053551 |
| RPLP1 | ribosomal protein, large, P1 | -0.0520817 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0520007 |
| DENND4A | DENN/MADD domain containing 4A | -0.0515616 |
| KYNU | kynureninase | -0.0503961 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0495832 |
| RPL19 | ribosomal protein L19 | -0.0488282 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0487501 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0462313 |
| ASPH | aspartate beta-hydroxylase | -0.045936 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0446052 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0443889 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0438519 |
| ZNF207 | zinc finger protein 207 | -0.0437095 |
| RBM39 | RNA binding motif protein 39 | -0.043486 |
| S100A10 | S100 calcium binding protein A10 | -0.0433511 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0428908 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0395828 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0391377 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0384871 |
| GNAS | GNAS complex locus | -0.0381296 |
| RHOA | ras homolog family member A | -0.037962 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0373632 |
| GLG1 | golgi glycoprotein 1 | -0.0370826 |
| SIK3 | SIK family kinase 3 | -0.0369177 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0366146 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0361797 |
| AHNAK | AHNAK nucleoprotein | -0.0360624 |
| UBC | ubiquitin C | -0.0360534 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0358687 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0357323 |
| PARD3 | par-3 family cell polarity regulator | -0.0357257 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0355335 |
| HDAC9 | histone deacetylase 9 | -0.0345883 |
| RASAL2 | RAS protein activator like 2 | -0.034357 |
| SVIL | supervillin | -0.0341813 |
| USP3 | ubiquitin specific peptidase 3 | -0.0340605 |
| RPLP0 | ribosomal protein, large, P0 | -0.0330511 |
| NOP58 | NOP58 ribonucleoprotein | -0.0330107 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0329551 |
| RPS25 | ribosomal protein S25 | -0.0327496 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0326817 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0322699 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0320851 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0319602 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0318812 |
| SETD5 | SET domain containing 5 | -0.031718 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0317063 |
| RPL35A | ribosomal protein L35a | -0.0316371 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0315666 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0313468 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0311115 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0310624 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.030784 |
| SMAD2 | SMAD family member 2 | -0.0306992 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0305658 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.030383 |
| USP34 | ubiquitin specific peptidase 34 | -0.0302405 |
| TPD52 | tumor protein D52 | -0.0301232 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0300902 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.02997 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0299562 |
| NRG1 | neuregulin 1 | -0.0299532 |
| FMNL2 | formin-like 2 | -0.0298186 |
| CAVIN1 | caveolae associated protein 1 | -0.0297632 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0297193 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0291746 |
| RHEB | Ras homolog enriched in brain | -0.0286897 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.028687 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0284884 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0280713 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0279408 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0275787 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0275707 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0275332 |
| TFG | TRK-fused gene | -0.0274813 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0274539 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0273022 |
| TLK1 | tousled-like kinase 1 | -0.0272353 |
