| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cilostazol perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cilostazol_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.113804 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0887109 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0544003 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0535749 |
| RPS3 | ribosomal protein S3 | 0.0509697 |
| NRCAM | neuronal cell adhesion molecule | 0.0502639 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0452509 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0416233 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0402818 |
| NEK7 | NIMA-related kinase 7 | 0.0385623 |
| MT2A | metallothionein 2A | 0.037347 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0366446 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0361213 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0342417 |
| RPL37A | ribosomal protein L37a | 0.0338068 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0337724 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0336318 |
| MATR3 | matrin 3 | 0.0331717 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0330107 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0329937 |
| RPS12 | ribosomal protein S12 | 0.0320707 |
| RPL23 | ribosomal protein L23 | 0.0318889 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0310766 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0298445 |
| PCBP3 | poly(rC) binding protein 3 | 0.0297477 |
| DST | dystonin | 0.0286305 |
| CTSC | cathepsin C | 0.0286209 |
| GRAMD1B | GRAM domain containing 1B | 0.0285594 |
| MKI67 | marker of proliferation Ki-67 | 0.0285031 |
| MSN | moesin | 0.0278349 |
| FLNB | filamin B, beta | 0.0254507 |
| ASPH | aspartate beta-hydroxylase | 0.0249814 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0248869 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0243782 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0242353 |
| RPL3 | ribosomal protein L3 | 0.0240738 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0231597 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0223027 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0222981 |
| STC2 | stanniocalcin 2 | 0.0222532 |
| RPL36 | ribosomal protein L36 | 0.021996 |
| FAM13A | family with sequence similarity 13, member A | 0.0218975 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0214792 |
| SET | SET nuclear proto-oncogene | 0.0209897 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0209817 |
| RPS18 | ribosomal protein S18 | 0.0205168 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0204496 |
| PNN | pinin, desmosome associated protein | 0.0204426 |
| ARRDC3 | arrestin domain containing 3 | 0.0201762 |
| FTL | ferritin, light polypeptide | 0.0200929 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0199577 |
| CST3 | cystatin C | 0.0198364 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0196863 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0193255 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0193016 |
| OGA | O-GlcNAcase | 0.0192502 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0191835 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0191326 |
| NCKAP1 | NCK-associated protein 1 | 0.019092 |
| FLNA | filamin A, alpha | 0.0190711 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0189523 |
| RNF145 | ring finger protein 145 | 0.0187483 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0186526 |
| LDHA | lactate dehydrogenase A | 0.0183983 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0182374 |
| TBXT | T-box transcription factor T | 0.01822 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.018119 |
| WDR43 | WD repeat domain 43 | 0.0180879 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0179525 |
| VEGFA | vascular endothelial growth factor A | 0.0179385 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0177909 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0175373 |
| FAT1 | FAT atypical cadherin 1 | 0.0173833 |
| MFF | mitochondrial fission factor | 0.0172362 |
| RAI1 | retinoic acid induced 1 | 0.0171719 |
| CD109 | CD109 molecule | 0.0171677 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0171488 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0170963 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0170047 |
| TMSB10 | thymosin beta 10 | 0.0169714 |
| TPR | translocated promoter region, nuclear basket protein | 0.0169594 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0168887 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0166939 |
| ENAH | enabled homolog (Drosophila) | 0.016673 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0165962 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0165573 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.016509 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0162398 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0162146 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0159492 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0159198 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0159125 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0158046 |
| ATP13A3 | ATPase type 13A3 | 0.015776 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0156934 |
| MFSD12 | major facilitator superfamily domain containing 12 | 0.0156652 |
| TPM3 | tropomyosin 3 | 0.0155767 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0152921 |
| RACK1 | receptor for activated C kinase 1 | 0.0150761 |
| RTN4 | reticulon 4 | 0.0150712 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.408237 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.206186 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.178928 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.138648 |
| VIM | vimentin | -0.108901 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0777702 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0734436 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0732516 |
| CANX | calnexin | -0.0677198 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0645966 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0619626 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0542616 |
| COL5A2 | collagen, type V, alpha 2 | -0.0540848 |
| KYNU | kynureninase | -0.0534287 |
| FN1 | fibronectin 1 | -0.0530426 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0524407 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0523132 |
| RPS24 | ribosomal protein S24 | -0.0513946 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.050934 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0488792 |
| VCL | vinculin | -0.048305 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0461184 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0450225 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0420807 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0420565 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0419247 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0415403 |
| RPLP1 | ribosomal protein, large, P1 | -0.0382667 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0355224 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0349775 |
| SMAD2 | SMAD family member 2 | -0.0348423 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0347403 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0345397 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0343436 |
| CUX1 | cut-like homeobox 1 | -0.0342066 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0329822 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0323862 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0323528 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0322608 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0315636 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0312341 |
| MAP7 | microtubule-associated protein 7 | -0.030746 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0298606 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0289156 |
| RPL35A | ribosomal protein L35a | -0.0288921 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0288086 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0281379 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0279194 |
| JMJD1C | jumonji domain containing 1C | -0.0274651 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0268763 |
| S100A6 | S100 calcium binding protein A6 | -0.026562 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0265219 |
| GNAS | GNAS complex locus | -0.0263533 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.026283 |
| LSAMP | limbic system-associated membrane protein | -0.0261355 |
| CDH13 | cadherin 13 | -0.0260632 |
| STC1 | stanniocalcin 1 | -0.0259623 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0258786 |
| RPL39 | ribosomal protein L39 | -0.0256817 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0255596 |
| UBC | ubiquitin C | -0.0254353 |
| RAB1A | RAB1A, member RAS oncogene family | -0.025337 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0252066 |
| ABLIM1 | actin binding LIM protein 1 | -0.0249921 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0249637 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0249102 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0247395 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0245922 |
| AHNAK | AHNAK nucleoprotein | -0.0242243 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0241298 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0240051 |
| S100A10 | S100 calcium binding protein A10 | -0.0238602 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0236981 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0235958 |
| RAB31 | RAB31, member RAS oncogene family | -0.0235023 |
| RPLP0 | ribosomal protein, large, P0 | -0.0230662 |
| SMYD3 | SET and MYND domain containing 3 | -0.0228896 |
| RIGI | RNA sensor RIG-I | -0.0226022 |
| NBEAL1 | neurobeachin-like 1 | -0.022178 |
| FBXO11 | F-box protein 11 | -0.0221455 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0220718 |
| SQSTM1 | sequestosome 1 | -0.0220428 |
| TPM4 | tropomyosin 4 | -0.021966 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0218711 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0218513 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0215899 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.021584 |
| MORF4L2 | mortality factor 4 like 2 | -0.0213633 |
| CHL1 | cell adhesion molecule L1-like | -0.0212449 |
| FNIP1 | folliculin interacting protein 1 | -0.0211495 |
| CADM2 | cell adhesion molecule 2 | -0.0209455 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.020801 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0207768 |
| RPL36A | ribosomal protein L36a | -0.0205609 |
| OXSR1 | oxidative stress responsive 1 | -0.0204665 |
| PCDH15 | protocadherin-related 15 | -0.0204364 |
| PYGL | phosphorylase, glycogen, liver | -0.0203564 |
| EPHA4 | EPH receptor A4 | -0.0202939 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0198617 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0197832 |
