Cimetidine Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach. (Chemical Entities of Biological Interest Ontology, CHEBI_3699)
External Link http://www.hmdb.ca/metabolites/HMDB14644
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Genes

23 interacting proteins for the Cimetidine metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
FMO1 flavin containing monooxygenase 1
FMO3 flavin containing monooxygenase 3
HRH2 histamine receptor H2
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC22A7 solute carrier family 22 (organic anion transporter), member 7