| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cinacalcet perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cinacalcet_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.152052 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0898056 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0852914 |
| LOXL2 | lysyl oxidase-like 2 | 0.0801764 |
| UBC | ubiquitin C | 0.0749086 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0741658 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0713389 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0658473 |
| CD44 | CD44 molecule (Indian blood group) | 0.0630539 |
| FBN1 | fibrillin 1 | 0.0613444 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0455647 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0448737 |
| PLAT | plasminogen activator, tissue | 0.0403042 |
| COL1A2 | collagen, type I, alpha 2 | 0.0381259 |
| SBF2 | SET binding factor 2 | 0.0380877 |
| OPTN | optineurin | 0.0378157 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0362813 |
| HIP1 | huntingtin interacting protein 1 | 0.0353749 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0348752 |
| GPC6 | glypican 6 | 0.0343292 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0335941 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0335619 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0334659 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.033213 |
| APP | amyloid beta (A4) precursor protein | 0.0322372 |
| CD109 | CD109 molecule | 0.0321313 |
| GOLGA4 | golgin A4 | 0.0319347 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0310431 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0307113 |
| OGA | O-GlcNAcase | 0.0306841 |
| RTN4 | reticulon 4 | 0.0306642 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.030348 |
| MB21D2 | Mab-21 domain containing 2 | 0.0302986 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0301123 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.029107 |
| ARRDC3 | arrestin domain containing 3 | 0.0289046 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0287355 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0286861 |
| FNIP1 | folliculin interacting protein 1 | 0.0275403 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0273788 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0273701 |
| COL3A1 | collagen, type III, alpha 1 | 0.0273177 |
| HELZ | helicase with zinc finger | 0.027313 |
| FNBP1L | formin binding protein 1-like | 0.0269158 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0268281 |
| SEPTIN9 | septin 9 | 0.026741 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0266561 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0262191 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0261985 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0260923 |
| UBAP1 | ubiquitin associated protein 1 | 0.0260267 |
| FLNB | filamin B, beta | 0.0251036 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0249355 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0248116 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0246031 |
| XPO1 | exportin 1 | 0.0245547 |
| SETD5 | SET domain containing 5 | 0.0239486 |
| NBAS | neuroblastoma amplified sequence | 0.0239361 |
| TMOD1 | tropomodulin 1 | 0.0239086 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0238093 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0237646 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0236889 |
| CTSB | cathepsin B | 0.0236779 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0235936 |
| NGLY1 | N-glycanase 1 | 0.0233266 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0232887 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0226435 |
| NAV2 | neuron navigator 2 | 0.022589 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0225327 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0225318 |
| STC1 | stanniocalcin 1 | 0.0224455 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0224445 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0223368 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0223036 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0220243 |
| KIAA1217 | KIAA1217 | 0.0219568 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0219113 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0218177 |
| DTNA | dystrobrevin, alpha | 0.0216945 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0216905 |
| ATXN1 | ataxin 1 | 0.0216465 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0215987 |
| C1D | C1D nuclear receptor corepressor | 0.0214664 |
| SEPTIN2 | septin 2 | 0.0213732 |
| SNX9 | sorting nexin 9 | 0.0213663 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0211093 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0210927 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0207817 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.020764 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0206076 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0203531 |
| YME1L1 | YME1-like 1 ATPase | 0.0203107 |
| STK10 | serine/threonine kinase 10 | 0.0201859 |
| ITSN2 | intersectin 2 | 0.019785 |
| ZNF654 | zinc finger protein 654 | 0.0196085 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.0194258 |
| THBS2 | thrombospondin 2 | 0.0193962 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0192844 |
| RNF24 | ring finger protein 24 | 0.0192432 |
| MTSS1 | metastasis suppressor 1 | 0.019182 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.182288 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.165078 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.151317 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.139636 |
| COL5A1 | collagen, type V, alpha 1 | -0.138972 |
| TMSB10 | thymosin beta 10 | -0.13038 |
| CDH13 | cadherin 13 | -0.125153 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.124179 |
| FN1 | fibronectin 1 | -0.101392 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0913046 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0867169 |
| AHNAK | AHNAK nucleoprotein | -0.0854465 |
| MAP1B | microtubule-associated protein 1B | -0.080573 |
| RIGI | RNA sensor RIG-I | -0.0732264 |
| NAV1 | neuron navigator 1 | -0.0694778 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0694762 |
| PTMA | prothymosin, alpha | -0.0691459 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0638417 |
| MX2 | MX dynamin-like GTPase 2 | -0.0607727 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0594067 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0562701 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0559061 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0549883 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0546805 |
| EGFR | epidermal growth factor receptor | -0.0545027 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.05366 |
| PODXL | podocalyxin-like | -0.0513158 |
| LMNA | lamin A/C | -0.0508167 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.049041 |
| POTEF | POTE ankyrin domain family, member F | -0.047349 |
| DCLK2 | doublecortin-like kinase 2 | -0.0471557 |
| MEIS2 | Meis homeobox 2 | -0.0467119 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0466519 |
| ASPH | aspartate beta-hydroxylase | -0.0452935 |
| TPM4 | tropomyosin 4 | -0.045135 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0447681 |
| VIM | vimentin | -0.0439919 |
| CANX | calnexin | -0.0438349 |
| SP100 | SP100 nuclear antigen | -0.0422908 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0418201 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.041491 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.041311 |
| CUX1 | cut-like homeobox 1 | -0.0412937 |
| DST | dystonin | -0.0399716 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0391892 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0381479 |
| EFNA5 | ephrin-A5 | -0.0379676 |
| CALR | calreticulin | -0.0374175 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.03717 |
| PRSS23 | protease, serine, 23 | -0.0364575 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0362906 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0359746 |
| TNS3 | tensin 3 | -0.0350921 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0348996 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0347132 |
| PLXNA2 | plexin A2 | -0.0342524 |
| TENM3 | teneurin transmembrane protein 3 | -0.0339711 |
| SRPK2 | SRSF protein kinase 2 | -0.0338209 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0333919 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0333608 |
| FSTL1 | follistatin-like 1 | -0.0329162 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0328712 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0325567 |
| IL7R | interleukin 7 receptor | -0.0325478 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0318683 |
| LOX | lysyl oxidase | -0.0317492 |
| ACTG1 | actin gamma 1 | -0.0311214 |
| RRBP1 | ribosome binding protein 1 | -0.0307101 |
| PCDH7 | protocadherin 7 | -0.030265 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0296113 |
| JAZF1 | JAZF zinc finger 1 | -0.0282889 |
| B2M | beta-2-microglobulin | -0.028288 |
| PKM | pyruvate kinase, muscle | -0.027297 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.02654 |
| ENO1 | enolase 1, (alpha) | -0.0264191 |
| PARD3 | par-3 family cell polarity regulator | -0.02627 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0261739 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0260225 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0255143 |
| CAVIN1 | caveolae associated protein 1 | -0.0254481 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0250509 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0250203 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0241155 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0240351 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0238527 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0237967 |
| TPM1 | tropomyosin 1 (alpha) | -0.0236143 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0235996 |
| RAD51B | RAD51 paralog B | -0.0230746 |
| RPS8 | ribosomal protein S8 | -0.022976 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0228007 |
| S100A10 | S100 calcium binding protein A10 | -0.022795 |
| GOLGB1 | golgin B1 | -0.022744 |
| NAV3 | neuron navigator 3 | -0.0225715 |
| RPS6 | ribosomal protein S6 | -0.0222793 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0221942 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.021953 |
| MSI2 | musashi RNA-binding protein 2 | -0.0217941 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0217304 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0214913 |
