| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cinacalcet perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cinacalcet_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMEM41B | transmembrane protein 41B | 0.0805219 |
| MMP12 | matrix metallopeptidase 12 | 0.0755309 |
| VMP1 | vacuole membrane protein 1 | 0.0725022 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0634448 |
| TXNRD1 | thioredoxin reductase 1 | 0.0572912 |
| JMJD1C | jumonji domain containing 1C | 0.0506959 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0428221 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0378567 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0370247 |
| UBC | ubiquitin C | 0.0365703 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0361572 |
| VIM | vimentin | 0.0353807 |
| GOLT1A | golgi transport 1A | 0.0322305 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0307286 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0303123 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0285919 |
| CLTC | clathrin, heavy chain (Hc) | 0.0285203 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0284884 |
| ECT2 | epithelial cell transforming 2 | 0.0280394 |
| TMEM123 | transmembrane protein 123 | 0.0277619 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0272853 |
| CCNL1 | cyclin L1 | 0.0270573 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0268873 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0265297 |
| ETNK1 | ethanolamine kinase 1 | 0.0263297 |
| THOC1 | THO complex 1 | 0.0262244 |
| PEG10 | paternally expressed 10 | 0.0250126 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0249389 |
| NEK7 | NIMA-related kinase 7 | 0.0245125 |
| COG5 | component of oligomeric golgi complex 5 | 0.0242883 |
| KLHL24 | kelch-like family member 24 | 0.024096 |
| BCHE | butyrylcholinesterase | 0.0234411 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0233656 |
| CEP95 | centrosomal protein 95kDa | 0.0230255 |
| MCL1 | myeloid cell leukemia 1 | 0.0224232 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.0223665 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0222288 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.0216063 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0213516 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0211897 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.021176 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.02088 |
| PCNP | PEST proteolytic signal containing nuclear protein | 0.0205799 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0200971 |
| MATR3 | matrin 3 | 0.020079 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0200163 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0199973 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0195352 |
| IL6ST | interleukin 6 signal transducer | 0.0194902 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0194722 |
| SMYD3 | SET and MYND domain containing 3 | 0.0193195 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0192648 |
| PREPL | prolyl endopeptidase-like | 0.0192401 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0191627 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0191311 |
| HEATR1 | HEAT repeat containing 1 | 0.0189404 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0189346 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.018525 |
| IPO7 | importin 7 | 0.0185227 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0181706 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0180271 |
| PCM1 | pericentriolar material 1 | 0.0178844 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.017207 |
| KLC1 | kinesin light chain 1 | 0.0168803 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0167078 |
| GCG | glucagon | 0.0166256 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0164899 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.016313 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0157163 |
| GMPS | guanine monphosphate synthase | 0.0156818 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0156699 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0155152 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0154474 |
| RPL36A | ribosomal protein L36a | 0.015426 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0154239 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0154135 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0150209 |
| FAM13B | family with sequence similarity 13, member B | 0.0149752 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0148835 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0148726 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0148718 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | 0.0148626 |
| CDC42SE2 | CDC42 small effector 2 | 0.0148352 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0147858 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | 0.0147702 |
| TSNAX | translin-associated factor X | 0.0147582 |
| RSF1 | remodeling and spacing factor 1 | 0.0145846 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0145833 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0145043 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.014494 |
| ETV5 | ets variant 5 | 0.0144257 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0142574 |
| SETD5 | SET domain containing 5 | 0.0141087 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0140513 |
| GASK1B | golgi associated kinase 1B | 0.014026 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0139252 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0139058 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0138597 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.013691 |
| CDK17 | cyclin-dependent kinase 17 | 0.0135838 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.155432 |
| NLGN1 | neuroligin 1 | -0.146506 |
| TMSB10 | thymosin beta 10 | -0.134053 |
| PTMA | prothymosin, alpha | -0.0958805 |
| DST | dystonin | -0.0721427 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0692719 |
| PCDH7 | protocadherin 7 | -0.065746 |
| RPL23 | ribosomal protein L23 | -0.0643076 |
| TPI1 | triosephosphate isomerase 1 | -0.0626973 |
| HMGA2 | high mobility group AT-hook 2 | -0.060572 |
| RPS8 | ribosomal protein S8 | -0.0527572 |
| RPS3 | ribosomal protein S3 | -0.052234 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0496363 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0484722 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0450552 |
| RPL19 | ribosomal protein L19 | -0.044157 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0424337 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0410131 |
| FTL | ferritin, light polypeptide | -0.0407155 |
| YBX3 | Y box binding protein 3 | -0.039958 |
| PFN1 | profilin 1 | -0.0397945 |
| RPL35A | ribosomal protein L35a | -0.039534 |
| EHBP1 | EH domain binding protein 1 | -0.0376622 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0373429 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0371862 |
| CBX3 | chromobox homolog 3 | -0.0369453 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0361729 |
| RNF213 | ring finger protein 213 | -0.0360826 |
| RASAL2 | RAS protein activator like 2 | -0.035938 |
| RPS12 | ribosomal protein S12 | -0.0359008 |
| RPS19 | ribosomal protein S19 | -0.0352534 |
| INTS6 | integrator complex subunit 6 | -0.0351682 |
| YBX1 | Y box binding protein 1 | -0.0350465 |
| RPL13A | ribosomal protein L13a | -0.0344186 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0343584 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0339402 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0337743 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0334582 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.033072 |
| RPLP1 | ribosomal protein, large, P1 | -0.0329896 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0321577 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0319728 |
| RPS27A | ribosomal protein S27a | -0.031915 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0312313 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0307012 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0306496 |
| TENM3 | teneurin transmembrane protein 3 | -0.0304241 |
| FSTL5 | follistatin-like 5 | -0.0301496 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0292287 |
| NEBL | nebulette | -0.0290788 |
| RPL36 | ribosomal protein L36 | -0.0290112 |
| HMGA1 | high mobility group AT-hook 1 | -0.0287767 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0282233 |
| RPL37A | ribosomal protein L37a | -0.0280898 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.0280136 |
| RPLP2 | ribosomal protein, large, P2 | -0.0278197 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0277367 |
| RACK1 | receptor for activated C kinase 1 | -0.0276642 |
| TPM3 | tropomyosin 3 | -0.0274958 |
| PCBP2 | poly(rC) binding protein 2 | -0.0269861 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0267892 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0267844 |
| CALR | calreticulin | -0.0266624 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0264759 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.026474 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0262906 |
| CDK6 | cyclin-dependent kinase 6 | -0.0259148 |
| GNAS | GNAS complex locus | -0.0258934 |
| RPL8 | ribosomal protein L8 | -0.0258668 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0254774 |
| RPL12 | ribosomal protein L12 | -0.0251085 |
| ZNF292 | zinc finger protein 292 | -0.0248123 |
| EZR | ezrin | -0.0247087 |
| SYT1 | synaptotagmin I | -0.0244204 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0243964 |
| RPS2 | ribosomal protein S2 | -0.0241378 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0241129 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0238298 |
| HMGB1 | high mobility group box 1 | -0.0237701 |
| CCDC88A | coiled-coil domain containing 88A | -0.0237568 |
| ANXA2 | annexin A2 | -0.023722 |
| RPS6 | ribosomal protein S6 | -0.0237103 |
| EXOC4 | exocyst complex component 4 | -0.0236368 |
| SPOP | speckle-type POZ protein | -0.0234478 |
| TBCA | tubulin folding cofactor A | -0.0234041 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0233674 |
| RPL26 | ribosomal protein L26 | -0.0231079 |
| CEP112 | centrosomal protein 112kDa | -0.0230855 |
| CCN2 | cellular communication network factor 2 | -0.0226439 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0223861 |
| RPS17 | ribosomal protein S17 | -0.0222749 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0222153 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.022051 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0219185 |
| SET | SET nuclear proto-oncogene | -0.0218627 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0216765 |
| ZNF804A | zinc finger protein 804A | -0.0212913 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.021063 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | -0.0209026 |
| RPL27 | ribosomal protein L27 | -0.0208192 |
