| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cinacalcet perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cinacalcet_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0644992 |
| MTSS1 | metastasis suppressor 1 | 0.0596161 |
| FLNB | filamin B, beta | 0.0563893 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0508732 |
| FOXO1 | forkhead box O1 | 0.0501691 |
| FN1 | fibronectin 1 | 0.0430261 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0407508 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0369772 |
| EFNA5 | ephrin-A5 | 0.0323816 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0308785 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0298283 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0293568 |
| FNIP1 | folliculin interacting protein 1 | 0.0274382 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0272036 |
| AOPEP | aminopeptidase O (putative) | 0.0266138 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0263613 |
| SULF1 | sulfatase 1 | 0.025266 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0249615 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0232811 |
| BLCAP | bladder cancer associated protein | 0.0230695 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0229238 |
| KIAA1217 | KIAA1217 | 0.0227414 |
| CD44 | CD44 molecule (Indian blood group) | 0.0223964 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0217662 |
| OSMR | oncostatin M receptor | 0.0214955 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0212572 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0212458 |
| RAI14 | retinoic acid induced 14 | 0.0209302 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0206826 |
| FRMD5 | FERM domain containing 5 | 0.0203246 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0203089 |
| STC1 | stanniocalcin 1 | 0.0200697 |
| PLAT | plasminogen activator, tissue | 0.0200592 |
| LUZP1 | leucine zipper protein 1 | 0.0194139 |
| VCL | vinculin | 0.0193015 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0192549 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0189574 |
| PRELID2 | PRELI domain containing 2 | 0.0189484 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.018927 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0187343 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0184422 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0180323 |
| RIN2 | Ras and Rab interactor 2 | 0.0178313 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0177201 |
| SMAD3 | SMAD family member 3 | 0.0174882 |
| NRG1 | neuregulin 1 | 0.0168868 |
| RAD51B | RAD51 paralog B | 0.016865 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0168227 |
| EHF | ets homologous factor | 0.0164297 |
| METTL15 | methyltransferase like 15 | 0.0162648 |
| LDLR | low density lipoprotein receptor | 0.0162397 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0161887 |
| SEPTIN9 | septin 9 | 0.0161061 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0157533 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0154496 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0153357 |
| KIF16B | kinesin family member 16B | 0.0152958 |
| DOK5 | docking protein 5 | 0.0152858 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0151627 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0149335 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0147408 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0146889 |
| CUL4B | cullin 4B | 0.0146689 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0145183 |
| ATXN1 | ataxin 1 | 0.0144818 |
| CNTNAP3 | contactin associated protein-like 3 | 0.014398 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0143448 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0143334 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0141314 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0140913 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0137186 |
| MYO9A | myosin IXA | 0.0136916 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0136738 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0134515 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | 0.0133355 |
| MCL1 | myeloid cell leukemia 1 | 0.0132804 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0132611 |
| NLRP1 | NLR family, pyrin domain containing 1 | 0.0131266 |
| CREB1 | cAMP responsive element binding protein 1 | 0.0130776 |
| CMIP | c-Maf inducing protein | 0.0129911 |
| LOXL2 | lysyl oxidase-like 2 | 0.0129069 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0128733 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0128688 |
| CLIC4 | chloride intracellular channel 4 | 0.0128403 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0128326 |
| VMP1 | vacuole membrane protein 1 | 0.0127642 |
| PODXL | podocalyxin-like | 0.0126382 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.0126101 |
| CLDN1 | claudin 1 | 0.0125989 |
| SYNJ2 | synaptojanin 2 | 0.0125839 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0124253 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0124062 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.012347 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0122739 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0122531 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0120834 |
| CDK6 | cyclin-dependent kinase 6 | 0.0120692 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0118368 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0118214 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0118144 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.111797 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0920372 |
| PTMA | prothymosin, alpha | -0.0824101 |
| MT2A | metallothionein 2A | -0.0786485 |
| RPS6 | ribosomal protein S6 | -0.0780381 |
| KRT17 | keratin 17, type I | -0.0753492 |
| ANXA1 | annexin A1 | -0.0659373 |
| LMNA | lamin A/C | -0.0523266 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0521975 |
| RPS8 | ribosomal protein S8 | -0.0520318 |
| RPS3 | ribosomal protein S3 | -0.0514599 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.048724 |
| RPS19 | ribosomal protein S19 | -0.0458315 |
| RPL11 | ribosomal protein L11 | -0.0453448 |
| RPS21 | ribosomal protein S21 | -0.0432995 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0425988 |
| RPLP1 | ribosomal protein, large, P1 | -0.0410182 |
| S100A10 | S100 calcium binding protein A10 | -0.0407226 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0404999 |
| YBX1 | Y box binding protein 1 | -0.0397595 |
| RPS12 | ribosomal protein S12 | -0.0396125 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0376717 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0368062 |
| LDHA | lactate dehydrogenase A | -0.0366604 |
| ENO1 | enolase 1, (alpha) | -0.035917 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0350689 |
| RPL23 | ribosomal protein L23 | -0.0347435 |
| RPL8 | ribosomal protein L8 | -0.0345636 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0343583 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0338964 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0334745 |
| RPS13 | ribosomal protein S13 | -0.0334126 |
| S100A2 | S100 calcium binding protein A2 | -0.0332035 |
| RPL12 | ribosomal protein L12 | -0.0321875 |
| RPL37 | ribosomal protein L37 | -0.0321781 |
| MT1X | metallothionein 1X | -0.0320502 |
| B2M | beta-2-microglobulin | -0.031675 |
| RPS2 | ribosomal protein S2 | -0.0315546 |
| CALR | calreticulin | -0.0314546 |
| YBX3 | Y box binding protein 3 | -0.0313856 |
| CANX | calnexin | -0.0304569 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0300517 |
| S100A9 | S100 calcium binding protein A9 | -0.0299338 |
| TMSB4X | thymosin beta 4, X-linked | -0.0299279 |
| EZR | ezrin | -0.0298192 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.029338 |
| MORF4L2 | mortality factor 4 like 2 | -0.0293005 |
| RPL13A | ribosomal protein L13a | -0.0290732 |
| RPL19 | ribosomal protein L19 | -0.0286778 |
| DSTN | destrin (actin depolymerizing factor) | -0.0286513 |
| RPLP2 | ribosomal protein, large, P2 | -0.0285003 |
| RPL36 | ribosomal protein L36 | -0.0281833 |
| PGK1 | phosphoglycerate kinase 1 | -0.0279071 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0278042 |
| GNAS | GNAS complex locus | -0.0272799 |
| TPM3 | tropomyosin 3 | -0.0271687 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0270913 |
| TAGLN2 | transgelin 2 | -0.0267959 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.026615 |
| RPL35 | ribosomal protein L35 | -0.0263927 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0263351 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0261025 |
| RPL7 | ribosomal protein L7 | -0.0258257 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | -0.0252246 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0249625 |
| S100A6 | S100 calcium binding protein A6 | -0.0248709 |
| TOP1 | topoisomerase (DNA) I | -0.02482 |
| PFN1 | profilin 1 | -0.0247889 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0245482 |
| SEC61G | Sec61 gamma subunit | -0.0242651 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0241889 |
| RPS4X | ribosomal protein S4, X-linked | -0.0239459 |
| RPL30 | ribosomal protein L30 | -0.0238513 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0236937 |
| EMP1 | epithelial membrane protein 1 | -0.0231743 |
| RPL5 | ribosomal protein L5 | -0.0229724 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0228529 |
| RACK1 | receptor for activated C kinase 1 | -0.0228184 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0227329 |
| ANXA2 | annexin A2 | -0.0227302 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0225037 |
| S100A11 | S100 calcium binding protein A11 | -0.0222513 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0220995 |
| RBM39 | RNA binding motif protein 39 | -0.0219219 |
| SEPTIN7 | septin 7 | -0.0219211 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0218969 |
| S100A4 | S100 calcium binding protein A4 | -0.0218291 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.021787 |
| RPN2 | ribophorin II | -0.0215955 |
| KRT14 | keratin 14, type I | -0.0213551 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0212484 |
| FTL | ferritin, light polypeptide | -0.0210871 |
| RPL18 | ribosomal protein L18 | -0.0209979 |
| PKM | pyruvate kinase, muscle | -0.0209936 |
| RPS20 | ribosomal protein S20 | -0.0207077 |
| RPL37A | ribosomal protein L37a | -0.0206736 |
| RPL32 | ribosomal protein L32 | -0.0206075 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0204646 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0204448 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0202525 |
