| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cinacalcet perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cinacalcet_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0690482 |
| FAM13A | family with sequence similarity 13, member A | 0.0643256 |
| VEGFA | vascular endothelial growth factor A | 0.0640395 |
| TXNIP | thioredoxin interacting protein | 0.0627566 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0560203 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0507145 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0450739 |
| RNF145 | ring finger protein 145 | 0.0447694 |
| EREG | epiregulin | 0.0443236 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0441654 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0356912 |
| WDR45B | WD repeat domain 45B | 0.0333144 |
| ANXA2 | annexin A2 | 0.0329443 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0321687 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0319177 |
| EZR | ezrin | 0.0315389 |
| CCNY | cyclin Y | 0.0307098 |
| FNBP1L | formin binding protein 1-like | 0.0271701 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0262126 |
| PCBP2 | poly(rC) binding protein 2 | 0.0249029 |
| GOLGA4 | golgin A4 | 0.0241057 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.023918 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0237778 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0230751 |
| SETD5 | SET domain containing 5 | 0.0221972 |
| RPL13A | ribosomal protein L13a | 0.021202 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0210192 |
| DSPP | dentin sialophosphoprotein | 0.0205934 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0204346 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0204335 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0201586 |
| NUP58 | nucleoporin 58 | 0.0201381 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0200077 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0199396 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0196761 |
| TMSB4X | thymosin beta 4, X-linked | 0.0194655 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0189637 |
| ANXA1 | annexin A1 | 0.0187595 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0187193 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0185047 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0183552 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0183528 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0182711 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0178744 |
| GDF15 | growth differentiation factor 15 | 0.0178726 |
| TSC22D2 | TSC22 domain family, member 2 | 0.017806 |
| XPOT | exportin, tRNA | 0.0177661 |
| INSIG1 | insulin induced gene 1 | 0.017666 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0176027 |
| TMEM41B | transmembrane protein 41B | 0.017373 |
| S100A14 | S100 calcium binding protein A14 | 0.0173041 |
| PDS5B | PDS5 cohesin associated factor B | 0.0171286 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0169306 |
| OXSR1 | oxidative stress responsive 1 | 0.0168903 |
| RREB1 | ras responsive element binding protein 1 | 0.0166842 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.016509 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0164868 |
| RLF | rearranged L-myc fusion | 0.0164827 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0164044 |
| MED13L | mediator complex subunit 13-like | 0.0163702 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0163581 |
| DNM2 | dynamin 2 | 0.016238 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.016021 |
| USP6NL | USP6 N-terminal like | 0.0159694 |
| CENPF | centromere protein F, 350/400kDa | 0.0159147 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0158812 |
| AFDN | afadin, adherens junction formation factor | 0.0158529 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0156619 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.015609 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0155772 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0155692 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0154906 |
| AREG | amphiregulin | 0.0154501 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.015335 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0152303 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0152211 |
| LMO7 | LIM domain 7 | 0.0151951 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0149053 |
| CCNL1 | cyclin L1 | 0.0148235 |
| LRRC1 | leucine rich repeat containing 1 | 0.0144276 |
| H2AC6 | H2A clustered histone 6 | 0.014292 |
| PGK1 | phosphoglycerate kinase 1 | 0.0138047 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0137454 |
| SUCO | SUN domain containing ossification factor | 0.0136095 |
| COPA | coatomer protein complex, subunit alpha | 0.0135566 |
| TPD52 | tumor protein D52 | 0.0135108 |
| YTHDC1 | YTH domain containing 1 | 0.0134516 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.0132206 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.013118 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0130657 |
| KLF6 | Kruppel-like factor 6 | 0.0129239 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0128792 |
| NCKAP1 | NCK-associated protein 1 | 0.0127869 |
| ITGA6 | integrin, alpha 6 | 0.0127485 |
| INSIG2 | insulin induced gene 2 | 0.012666 |
| RBM39 | RNA binding motif protein 39 | 0.0125442 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0125414 |
| PNN | pinin, desmosome associated protein | 0.0124965 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 0.0123971 |
| LIPH | lipase, member H | 0.0123032 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.155895 |
| PTMA | prothymosin, alpha | -0.110515 |
| AHNAK | AHNAK nucleoprotein | -0.0955979 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0955977 |
| NPSR1 | neuropeptide S receptor 1 | -0.0874792 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0867864 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0824253 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0813124 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0735079 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0734536 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.071121 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0666626 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0661147 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0651364 |
| RPS27A | ribosomal protein S27a | -0.0554565 |
| SMYD3 | SET and MYND domain containing 3 | -0.0553199 |
| FHIT | fragile histidine triad | -0.0533648 |
| RPL23 | ribosomal protein L23 | -0.0528135 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0503428 |
| FAT1 | FAT atypical cadherin 1 | -0.0497362 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0478312 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0472356 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0466403 |
| TMSB10 | thymosin beta 10 | -0.0456263 |
| CADPS | Ca++-dependent secretion activator | -0.0449361 |
| RPS8 | ribosomal protein S8 | -0.0443449 |
| KRT8 | keratin 8, type II | -0.0427645 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0420962 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0417467 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0408905 |
| GPHN | gephyrin | -0.0401291 |
| RAD51B | RAD51 paralog B | -0.0384759 |
| ACTG1 | actin gamma 1 | -0.0376213 |
| VCL | vinculin | -0.0375726 |
| RPS24 | ribosomal protein S24 | -0.0345089 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0338299 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0337072 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0334602 |
| MYO1E | myosin IE | -0.0333307 |
| CD44 | CD44 molecule (Indian blood group) | -0.0328236 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0327519 |
| FOXP1 | forkhead box P1 | -0.0317124 |
| ACTN4 | actinin, alpha 4 | -0.0317094 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0316803 |
| RPL34 | ribosomal protein L34 | -0.0314729 |
| ONECUT3 | one cut homeobox 3 | -0.0306138 |
| MYO1D | myosin ID | -0.0304579 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0300708 |
| UBC | ubiquitin C | -0.02972 |
| RPL26 | ribosomal protein L26 | -0.0295077 |
| RPLP1 | ribosomal protein, large, P1 | -0.0285316 |
| EXOC4 | exocyst complex component 4 | -0.0284481 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0276359 |
| RPL9 | ribosomal protein L9 | -0.0275495 |
| RAB10 | RAB10, member RAS oncogene family | -0.0274541 |
| RPLP2 | ribosomal protein, large, P2 | -0.0265228 |
| ASPH | aspartate beta-hydroxylase | -0.0261827 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0261451 |
| S100A6 | S100 calcium binding protein A6 | -0.0260651 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0258862 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0255027 |
| CALR | calreticulin | -0.0250936 |
| ENO1 | enolase 1, (alpha) | -0.0250034 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0247955 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0245851 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0245616 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0244393 |
| NRXN3 | neurexin 3 | -0.023845 |
| RPL31 | ribosomal protein L31 | -0.0235865 |
| DIAPH2 | diaphanous-related formin 2 | -0.0235143 |
| RPS25 | ribosomal protein S25 | -0.0224884 |
| CANX | calnexin | -0.022335 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0222578 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0222474 |
| MECOM | MDS1 and EVI1 complex locus | -0.0220957 |
| MSI2 | musashi RNA-binding protein 2 | -0.0220609 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0219111 |
| RPS19 | ribosomal protein S19 | -0.0212739 |
| RPS23 | ribosomal protein S23 | -0.0210938 |
| RPS6 | ribosomal protein S6 | -0.0207053 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0206614 |
| FRMD5 | FERM domain containing 5 | -0.0206504 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0204562 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.02044 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0203699 |
| CCND1 | cyclin D1 | -0.0203515 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0201107 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0200004 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0199993 |
| RPS17 | ribosomal protein S17 | -0.0199739 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0197422 |
| EXOC6B | exocyst complex component 6B | -0.0197239 |
| RPL4 | ribosomal protein L4 | -0.0196503 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0196054 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0193413 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0193047 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0192446 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0191117 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0189882 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0189162 |
