| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cinacalcet perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cinacalcet_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.291716 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.201321 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.156545 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.153465 |
| TMSB4X | thymosin beta 4, X-linked | 0.113564 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.108779 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.100539 |
| CD44 | CD44 molecule (Indian blood group) | 0.0950791 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0877291 |
| EHBP1 | EH domain binding protein 1 | 0.0786486 |
| CANX | calnexin | 0.0782961 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0753054 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0726023 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0704884 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0645682 |
| EFNA5 | ephrin-A5 | 0.063555 |
| PGK1 | phosphoglycerate kinase 1 | 0.0631984 |
| MYOF | myoferlin | 0.0564247 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.054567 |
| LDHA | lactate dehydrogenase A | 0.054206 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0531984 |
| PLK2 | polo-like kinase 2 | 0.0508998 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0483165 |
| EPHA4 | EPH receptor A4 | 0.0482925 |
| APP | amyloid beta (A4) precursor protein | 0.0471646 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0471377 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0450986 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0450261 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0445658 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0445292 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0438583 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0419514 |
| RAI1 | retinoic acid induced 1 | 0.0403418 |
| UBC | ubiquitin C | 0.0400833 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0391205 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0384578 |
| TMEM123 | transmembrane protein 123 | 0.0371947 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0363517 |
| PCBP2 | poly(rC) binding protein 2 | 0.0363229 |
| PLIN2 | perilipin 2 | 0.0349768 |
| LRRC49 | leucine rich repeat containing 49 | 0.0348044 |
| TXNIP | thioredoxin interacting protein | 0.0346976 |
| TNS3 | tensin 3 | 0.0343919 |
| KLF6 | Kruppel-like factor 6 | 0.033162 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0327699 |
| CALR | calreticulin | 0.0322941 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0317871 |
| FNIP1 | folliculin interacting protein 1 | 0.0316731 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0314499 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0313367 |
| JUN | jun proto-oncogene | 0.0306286 |
| ARF6 | ADP-ribosylation factor 6 | 0.0304704 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0303692 |
| TOP1 | topoisomerase (DNA) I | 0.0302314 |
| HDLBP | high density lipoprotein binding protein | 0.0301155 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0297028 |
| AFF4 | AF4/FMR2 family, member 4 | 0.029605 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0291845 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0291682 |
| EREG | epiregulin | 0.028917 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0281837 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0276054 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0270753 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0268591 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0265277 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0264724 |
| CD109 | CD109 molecule | 0.0264159 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0263933 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0260918 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0260273 |
| DENND1A | DENN/MADD domain containing 1A | 0.025972 |
| RNF213 | ring finger protein 213 | 0.0259475 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0257486 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0253731 |
| LOXL2 | lysyl oxidase-like 2 | 0.0253618 |
| SZRD1 | SUZ RNA binding domain containing 1 | 0.025337 |
| AHNAK | AHNAK nucleoprotein | 0.0251887 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0251765 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0249425 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0248877 |
| HDAC9 | histone deacetylase 9 | 0.0243487 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.023727 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0233117 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0232668 |
| XPOT | exportin, tRNA | 0.0231875 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0230124 |
| NDRG1 | N-myc downstream regulated 1 | 0.0229536 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0220968 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0220903 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.021908 |
| ANXA2 | annexin A2 | 0.0218414 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0214964 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0214683 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0214455 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.021372 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0210671 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0209324 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0209115 |
| CDK19 | cyclin-dependent kinase 19 | 0.0208241 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0205145 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.159205 |
| MT2A | metallothionein 2A | -0.148721 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.1089 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0733738 |
| RPS2 | ribosomal protein S2 | -0.0732405 |
| RPS8 | ribosomal protein S8 | -0.0677598 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0668956 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0661411 |
| RPS19 | ribosomal protein S19 | -0.0612084 |
| TP63 | tumor protein p63 | -0.0598571 |
| RPL23 | ribosomal protein L23 | -0.0520958 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0507608 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0500701 |
| CENPF | centromere protein F, 350/400kDa | -0.0479167 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0466984 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0460817 |
| RPS6 | ribosomal protein S6 | -0.0449972 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0447917 |
| RPL26 | ribosomal protein L26 | -0.0443559 |
| RPL36 | ribosomal protein L36 | -0.0441073 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.042875 |
| RBM39 | RNA binding motif protein 39 | -0.0424908 |
| RPS12 | ribosomal protein S12 | -0.0416635 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.040971 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0397548 |
| YBX3 | Y box binding protein 3 | -0.0394952 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0393265 |
| EMP1 | epithelial membrane protein 1 | -0.0380922 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.037986 |
| RPL38 | ribosomal protein L38 | -0.0378825 |
| SRPK2 | SRSF protein kinase 2 | -0.0377244 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0376001 |
| RPL37A | ribosomal protein L37a | -0.0368676 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0368416 |
| RPL19 | ribosomal protein L19 | -0.0366483 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0344239 |
| RPL35A | ribosomal protein L35a | -0.0344014 |
| RPL12 | ribosomal protein L12 | -0.0339196 |
| SPAG9 | sperm associated antigen 9 | -0.0335954 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0331787 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0325021 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0314226 |
| YBX1 | Y box binding protein 1 | -0.0310335 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0309587 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0303521 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0293828 |
| CAPRIN2 | caprin family member 2 | -0.0293423 |
| SEPTIN7 | septin 7 | -0.0292996 |
| JMJD1C | jumonji domain containing 1C | -0.0292926 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0289059 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0280678 |
| HMGB2 | high mobility group box 2 | -0.0276278 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0276252 |
| ZNF292 | zinc finger protein 292 | -0.0268865 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0265778 |
| NOP58 | NOP58 ribonucleoprotein | -0.026429 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0262992 |
| FTL | ferritin, light polypeptide | -0.0260019 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0259495 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0254854 |
| SQSTM1 | sequestosome 1 | -0.0250781 |
| RPL34 | ribosomal protein L34 | -0.0247408 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0246937 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0246476 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0243149 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0243141 |
| RPS3 | ribosomal protein S3 | -0.0240226 |
| RPS13 | ribosomal protein S13 | -0.0239465 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.023683 |
| PKM | pyruvate kinase, muscle | -0.0235778 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0233607 |
| PRDX1 | peroxiredoxin 1 | -0.0232571 |
| RPL11 | ribosomal protein L11 | -0.0230352 |
| FUS | FUS RNA binding protein | -0.0229366 |
| BRD2 | bromodomain containing 2 | -0.0227541 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0226895 |
| FERMT1 | fermitin family member 1 | -0.0224576 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0221522 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0220588 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0220389 |
| RPL13A | ribosomal protein L13a | -0.022013 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0218567 |
| RPL7 | ribosomal protein L7 | -0.0217695 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0216609 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0216077 |
| RPS17 | ribosomal protein S17 | -0.0215933 |
| CDC73 | cell division cycle 73 | -0.0214432 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0209846 |
| USP34 | ubiquitin specific peptidase 34 | -0.0209473 |
| CEP170 | centrosomal protein 170kDa | -0.0209335 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0209256 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0208659 |
| RPS18 | ribosomal protein S18 | -0.0207753 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0205487 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0204991 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0204967 |
| SET | SET nuclear proto-oncogene | -0.0204619 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0202334 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0201533 |
| RPS10 | ribosomal protein S10 | -0.0200546 |
