| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cinacalcet perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cinacalcet_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.122147 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.116817 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.106227 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.106132 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.105431 |
| TXNRD1 | thioredoxin reductase 1 | 0.0969995 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0879224 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0790977 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0726148 |
| RAD51B | RAD51 paralog B | 0.0697 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0669969 |
| USP34 | ubiquitin specific peptidase 34 | 0.0615335 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0579213 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0574015 |
| MCL1 | myeloid cell leukemia 1 | 0.0571539 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0550488 |
| PCBP2 | poly(rC) binding protein 2 | 0.0517373 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0505658 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.048585 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0467075 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0458082 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0456114 |
| BBX | bobby sox homolog (Drosophila) | 0.0452482 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0445905 |
| ZNF638 | zinc finger protein 638 | 0.0407765 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0387068 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.038541 |
| OGA | O-GlcNAcase | 0.0382238 |
| RTN4 | reticulon 4 | 0.0377541 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0376969 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0372803 |
| PKM | pyruvate kinase, muscle | 0.0371047 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0364555 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0364485 |
| MSN | moesin | 0.0364213 |
| UBC | ubiquitin C | 0.0361734 |
| ANO6 | anoctamin 6 | 0.036058 |
| NUP58 | nucleoporin 58 | 0.0359366 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0356512 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0351759 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0344467 |
| NF1 | neurofibromin 1 | 0.0334373 |
| MMP12 | matrix metallopeptidase 12 | 0.0333973 |
| XPOT | exportin, tRNA | 0.0333151 |
| STRN | striatin, calmodulin binding protein | 0.0328603 |
| PRKCE | protein kinase C, epsilon | 0.032663 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0322407 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0321318 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0320589 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0318721 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0318622 |
| PNN | pinin, desmosome associated protein | 0.03147 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0313304 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0310518 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.0308039 |
| JMJD1C | jumonji domain containing 1C | 0.0306418 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0303816 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0302776 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0302559 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.030038 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0299564 |
| MAP4 | microtubule-associated protein 4 | 0.0298535 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0296566 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0295511 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0294674 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0291982 |
| CTTN | cortactin | 0.0291268 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0290735 |
| PER1 | period circadian clock 1 | 0.0287896 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0286609 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.028621 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0286207 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0285881 |
| ENO1 | enolase 1, (alpha) | 0.0285478 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0282214 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0279005 |
| PGK1 | phosphoglycerate kinase 1 | 0.0277498 |
| MED13L | mediator complex subunit 13-like | 0.0276116 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0274155 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0272863 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0270565 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0270096 |
| MYPN | myopalladin | 0.0266759 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0266322 |
| ATXN2 | ataxin 2 | 0.0265434 |
| CDK19 | cyclin-dependent kinase 19 | 0.0264401 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0262977 |
| GLG1 | golgi glycoprotein 1 | 0.02596 |
| ENAH | enabled homolog (Drosophila) | 0.0255972 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0254848 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0254683 |
| KIAA1328 | KIAA1328 | 0.0253181 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0252078 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0251151 |
| MED13 | mediator complex subunit 13 | 0.0250866 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0249327 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0247662 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0247288 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0246263 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0244638 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.135447 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0918547 |
| TMSB10 | thymosin beta 10 | -0.0909971 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0736889 |
| RPL23 | ribosomal protein L23 | -0.0630158 |
| YBX1 | Y box binding protein 1 | -0.0617351 |
| RPS19 | ribosomal protein S19 | -0.0586325 |
| VIM | vimentin | -0.0572802 |
| RPL35A | ribosomal protein L35a | -0.0562733 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0534736 |
| RPLP1 | ribosomal protein, large, P1 | -0.0516239 |
| RPS8 | ribosomal protein S8 | -0.0475547 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0468039 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0430163 |
| GNAS | GNAS complex locus | -0.0429244 |
| RPL12 | ribosomal protein L12 | -0.041413 |
| AHNAK | AHNAK nucleoprotein | -0.0398185 |
| TPR | translocated promoter region, nuclear basket protein | -0.0392546 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0390888 |
| OSMR | oncostatin M receptor | -0.039062 |
| RPS21 | ribosomal protein S21 | -0.0383593 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0371377 |
| RPL26 | ribosomal protein L26 | -0.036657 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0365619 |
| FTL | ferritin, light polypeptide | -0.0358628 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0357353 |
| MT2A | metallothionein 2A | -0.0353806 |
| RPL34 | ribosomal protein L34 | -0.0343412 |
| RPL37A | ribosomal protein L37a | -0.0341573 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0328729 |
| WWOX | WW domain containing oxidoreductase | -0.0323722 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0322013 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0319556 |
| RPL11 | ribosomal protein L11 | -0.0312671 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0312642 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0308448 |
| RPS12 | ribosomal protein S12 | -0.0305799 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0296712 |
| RPL27 | ribosomal protein L27 | -0.029349 |
| RPS24 | ribosomal protein S24 | -0.0283349 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.027972 |
| RPS27 | ribosomal protein S27 | -0.0278028 |
| RPL36 | ribosomal protein L36 | -0.0273298 |
| RPL19 | ribosomal protein L19 | -0.027329 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0270914 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0270855 |
| RRBP1 | ribosome binding protein 1 | -0.0269981 |
| RPL31 | ribosomal protein L31 | -0.026857 |
| RPS14 | ribosomal protein S14 | -0.0267801 |
| RPS3 | ribosomal protein S3 | -0.0267523 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0262035 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0256946 |
| RPS29 | ribosomal protein S29 | -0.0256257 |
| RPS6 | ribosomal protein S6 | -0.0254217 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0251186 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0250433 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0245452 |
| RPS20 | ribosomal protein S20 | -0.0245233 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.0245105 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0243839 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0238558 |
| RPS27A | ribosomal protein S27a | -0.0234305 |
| RPL37 | ribosomal protein L37 | -0.0230953 |
| RPL13A | ribosomal protein L13a | -0.0226049 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0225192 |
| RPL18 | ribosomal protein L18 | -0.0222371 |
| RPL36A | ribosomal protein L36a | -0.0218459 |
| RPL9 | ribosomal protein L9 | -0.0215979 |
| RBM39 | RNA binding motif protein 39 | -0.0213944 |
| H1-0 | H1.0 linker histone | -0.0212433 |
| RPL30 | ribosomal protein L30 | -0.0210882 |
| HMGA1 | high mobility group AT-hook 1 | -0.0207962 |
| LDHB | lactate dehydrogenase B | -0.0205598 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0204167 |
| GTPBP4 | GTP binding protein 4 | -0.020359 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0203393 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0202287 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0199405 |
| RPLP2 | ribosomal protein, large, P2 | -0.01993 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0196909 |
| RPS13 | ribosomal protein S13 | -0.0196624 |
| SEC61G | Sec61 gamma subunit | -0.0195618 |
| TOP1 | topoisomerase (DNA) I | -0.0190067 |
| ZCRB1 | zinc finger CCHC-type and RNA binding motif 1 | -0.0188927 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0188137 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0187571 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0185561 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0185354 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0185251 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.0184136 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0183959 |
| RPS25 | ribosomal protein S25 | -0.0183657 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0183567 |
| DEK | DEK proto-oncogene | -0.0182447 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0180762 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0180156 |
| DIDO1 | death inducer-obliterator 1 | -0.0179623 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0177384 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0177248 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0177018 |
