| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cinacalcet perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cinacalcet_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.290865 |
| NDRG1 | N-myc downstream regulated 1 | 0.112743 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.108258 |
| FNDC3B | fibronectin type III domain containing 3B | 0.10049 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0946696 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.086867 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0777394 |
| CCNL1 | cyclin L1 | 0.0723583 |
| FAM13A | family with sequence similarity 13, member A | 0.0683465 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0675651 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0656846 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.064591 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0623586 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0616744 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0595425 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0585241 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.056622 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0560157 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0542185 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0527858 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0527574 |
| TFG | TRK-fused gene | 0.0512496 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0508487 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0500696 |
| ASPH | aspartate beta-hydroxylase | 0.0479928 |
| MATR3 | matrin 3 | 0.047733 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0472187 |
| UBC | ubiquitin C | 0.0469475 |
| CDC73 | cell division cycle 73 | 0.0468283 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0467306 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0466721 |
| TXNRD1 | thioredoxin reductase 1 | 0.0466556 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0465332 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0453546 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0449681 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0441984 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.044059 |
| USP3 | ubiquitin specific peptidase 3 | 0.0431415 |
| PGK1 | phosphoglycerate kinase 1 | 0.0422091 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0419362 |
| PTK2 | protein tyrosine kinase 2 | 0.0414483 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.041165 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0411341 |
| ARRDC3 | arrestin domain containing 3 | 0.0410485 |
| SLMAP | sarcolemma associated protein | 0.0408219 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0400202 |
| CLINT1 | clathrin interactor 1 | 0.0393331 |
| RNF145 | ring finger protein 145 | 0.0392965 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0390093 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0387768 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0380493 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0378629 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0376818 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.037616 |
| COPA | coatomer protein complex, subunit alpha | 0.0372795 |
| YTHDC1 | YTH domain containing 1 | 0.0369703 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0367868 |
| GOLGA4 | golgin A4 | 0.0367225 |
| PARD3 | par-3 family cell polarity regulator | 0.0365835 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0361448 |
| ZNF292 | zinc finger protein 292 | 0.0361337 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.03613 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0360197 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0358282 |
| CANX | calnexin | 0.0347762 |
| SPAG9 | sperm associated antigen 9 | 0.0343375 |
| CDK17 | cyclin-dependent kinase 17 | 0.0342233 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0340975 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0336575 |
| VMP1 | vacuole membrane protein 1 | 0.0331986 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0331986 |
| RLF | rearranged L-myc fusion | 0.0331648 |
| CD109 | CD109 molecule | 0.0331292 |
| HELZ | helicase with zinc finger | 0.0330945 |
| RBM39 | RNA binding motif protein 39 | 0.0330636 |
| FAM3C | family with sequence similarity 3, member C | 0.0327553 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0324528 |
| IRF6 | interferon regulatory factor 6 | 0.0320274 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0320254 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0313559 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0312611 |
| NCKAP1 | NCK-associated protein 1 | 0.0312262 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0311197 |
| RTN4 | reticulon 4 | 0.0310499 |
| ANXA5 | annexin A5 | 0.0309433 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0308955 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0308584 |
| PAPOLA | poly(A) polymerase alpha | 0.0308561 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0308407 |
| NUP58 | nucleoporin 58 | 0.030608 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0305451 |
| IL6ST | interleukin 6 signal transducer | 0.0304369 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0304044 |
| QKI | QKI, KH domain containing, RNA binding | 0.030278 |
| RYBP | RING1 and YY1 binding protein | 0.0302213 |
| RHEB | Ras homolog enriched in brain | 0.0299862 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0299671 |
| RBM25 | RNA binding motif protein 25 | 0.0299335 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0299002 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0297852 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.151918 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.109732 |
| PTMA | prothymosin, alpha | -0.102465 |
| TMSB10 | thymosin beta 10 | -0.0995309 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0989723 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0949406 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0893661 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0762728 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0755361 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.063184 |
| EFNA5 | ephrin-A5 | -0.0581918 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0555424 |
| RNF213 | ring finger protein 213 | -0.0532778 |
| ACTG1 | actin gamma 1 | -0.0523218 |
| FBXO32 | F-box protein 32 | -0.0510967 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0488469 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0487127 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0482648 |
| MT2A | metallothionein 2A | -0.0479884 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0478289 |
| RPL35A | ribosomal protein L35a | -0.0466331 |
| G0S2 | G0/G1 switch 2 | -0.0464603 |
| MX2 | MX dynamin-like GTPase 2 | -0.0445645 |
| AHNAK | AHNAK nucleoprotein | -0.0438782 |
| RAI14 | retinoic acid induced 14 | -0.0438526 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0426171 |
| RPS19 | ribosomal protein S19 | -0.0405327 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0398869 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0393643 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0389229 |
| RIGI | RNA sensor RIG-I | -0.0378128 |
| FHIT | fragile histidine triad | -0.0374836 |
| RAD51B | RAD51 paralog B | -0.0373506 |
| GOLGB1 | golgin B1 | -0.0370867 |
| NAV2 | neuron navigator 2 | -0.0364687 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0362259 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0360322 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0359871 |
| RRBP1 | ribosome binding protein 1 | -0.0356753 |
| RPLP1 | ribosomal protein, large, P1 | -0.0355071 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0354559 |
| RPL23 | ribosomal protein L23 | -0.0347827 |
| S100A10 | S100 calcium binding protein A10 | -0.0345702 |
| DSPP | dentin sialophosphoprotein | -0.0341479 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.034029 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.033458 |
| RPL19 | ribosomal protein L19 | -0.033445 |
| ENO1 | enolase 1, (alpha) | -0.0332414 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0331674 |
| MX1 | MX dynamin-like GTPase 1 | -0.0330419 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.032981 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0328576 |
| RPL34 | ribosomal protein L34 | -0.0323546 |
| RPL37A | ribosomal protein L37a | -0.0311773 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0308056 |
| HMGA1 | high mobility group AT-hook 1 | -0.0290508 |
| S100A9 | S100 calcium binding protein A9 | -0.0287054 |
| ETV6 | ets variant 6 | -0.028206 |
| RPL36 | ribosomal protein L36 | -0.0281988 |
| RPS3 | ribosomal protein S3 | -0.0280209 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0278665 |
| SQSTM1 | sequestosome 1 | -0.0278412 |
| SP100 | SP100 nuclear antigen | -0.0275449 |
| ATXN1 | ataxin 1 | -0.0274297 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0272019 |
| CSTB | cystatin B (stefin B) | -0.0270713 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0269773 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0268862 |
| ATP11A | ATPase, class VI, type 11A | -0.0267566 |
| RPS6 | ribosomal protein S6 | -0.026514 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0264681 |
| TBCA | tubulin folding cofactor A | -0.0258445 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0257363 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0253927 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0246118 |
| RPS8 | ribosomal protein S8 | -0.024565 |
| PKM | pyruvate kinase, muscle | -0.0241618 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0237317 |
| PLSCR1 | phospholipid scramblase 1 | -0.0237275 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0233394 |
| RPL8 | ribosomal protein L8 | -0.0229479 |
| LMNA | lamin A/C | -0.0229039 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0227794 |
| RPS27A | ribosomal protein S27a | -0.0227059 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0226179 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0225922 |
| EGFR | epidermal growth factor receptor | -0.022564 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0225229 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0224947 |
| BPTF | bromodomain PHD finger transcription factor | -0.0222286 |
| FRMD5 | FERM domain containing 5 | -0.0222162 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0221289 |
| INTS6 | integrator complex subunit 6 | -0.0220365 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.021731 |
| HLA-B | major histocompatibility complex, class I, B | -0.0217064 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0216655 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0216624 |
| RPS27 | ribosomal protein S27 | -0.0216222 |
| CUX1 | cut-like homeobox 1 | -0.0216077 |
| RPL9 | ribosomal protein L9 | -0.0215713 |
