| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cinacalcet perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cinacalcet_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.134289 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0985778 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0886853 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.065408 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0548651 |
| CD44 | CD44 molecule (Indian blood group) | 0.051447 |
| NAV2 | neuron navigator 2 | 0.0508102 |
| ATXN1 | ataxin 1 | 0.0456319 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0435726 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0431165 |
| HDAC9 | histone deacetylase 9 | 0.0424882 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0423163 |
| VCL | vinculin | 0.0405555 |
| COL6A3 | collagen, type VI, alpha 3 | 0.039889 |
| TNS3 | tensin 3 | 0.0394218 |
| FNIP1 | folliculin interacting protein 1 | 0.0392844 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0382086 |
| DST | dystonin | 0.0375931 |
| SMAD3 | SMAD family member 3 | 0.0371769 |
| PDE10A | phosphodiesterase 10A | 0.0368957 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0361993 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0357237 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0350814 |
| JMJD1C | jumonji domain containing 1C | 0.033558 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0330589 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0325197 |
| KYNU | kynureninase | 0.0277452 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0276207 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0273509 |
| ARFGEF3 | ARFGEF family member 3 | 0.027227 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0268705 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0255442 |
| NAV1 | neuron navigator 1 | 0.025184 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0240673 |
| HMGA2 | high mobility group AT-hook 2 | 0.0239569 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0239424 |
| GPC6 | glypican 6 | 0.0229424 |
| VMP1 | vacuole membrane protein 1 | 0.0228411 |
| SMYD3 | SET and MYND domain containing 3 | 0.0226808 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0224628 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0221268 |
| MYOF | myoferlin | 0.0220523 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0219023 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0215448 |
| VCAN | versican | 0.0215333 |
| CDK19 | cyclin-dependent kinase 19 | 0.0214118 |
| SYNJ2 | synaptojanin 2 | 0.0212014 |
| MSN | moesin | 0.0210337 |
| CDCP1 | CUB domain containing protein 1 | 0.0209027 |
| PRELID2 | PRELI domain containing 2 | 0.0208468 |
| OSMR | oncostatin M receptor | 0.0202604 |
| AHNAK | AHNAK nucleoprotein | 0.0201999 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0201026 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0200891 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0199479 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0199339 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0198756 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0197772 |
| GOLGB1 | golgin B1 | 0.0191588 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0191419 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0189742 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0189084 |
| MLPH | melanophilin | 0.0189069 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0186729 |
| GLIS3 | GLIS family zinc finger 3 | 0.0185259 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0184778 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0183997 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0182671 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0182168 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0181743 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0179069 |
| PCBP3 | poly(rC) binding protein 3 | 0.0178712 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0178703 |
| PHF3 | PHD finger protein 3 | 0.0178408 |
| SVIL | supervillin | 0.0175266 |
| BPTF | bromodomain PHD finger transcription factor | 0.0174024 |
| ASPH | aspartate beta-hydroxylase | 0.017337 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.017229 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.017104 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0171001 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.017073 |
| MYO9A | myosin IXA | 0.0170395 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.016933 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0168846 |
| SEPTIN9 | septin 9 | 0.0165707 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0164517 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0162695 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0161511 |
| MKI67 | marker of proliferation Ki-67 | 0.0160753 |
| SLC35F3 | solute carrier family 35, member F3 | 0.016017 |
| UTRN | utrophin | 0.0159662 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0158628 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0158535 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0155927 |
| RAD51B | RAD51 paralog B | 0.0155636 |
| KLF12 | Kruppel-like factor 12 | 0.0155393 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0153076 |
| FHIT | fragile histidine triad | 0.0152886 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0151274 |
| AFDN | afadin, adherens junction formation factor | 0.015018 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.168327 |
| FTL | ferritin, light polypeptide | -0.107628 |
| VIM | vimentin | -0.0879895 |
| RPS6 | ribosomal protein S6 | -0.0791137 |
| TMSB10 | thymosin beta 10 | -0.0790925 |
| RPS12 | ribosomal protein S12 | -0.0714541 |
| HLA-B | major histocompatibility complex, class I, B | -0.0667883 |
| PTMA | prothymosin, alpha | -0.065553 |
| RPS3 | ribosomal protein S3 | -0.0584819 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0554371 |
| B2M | beta-2-microglobulin | -0.0545757 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0540025 |
| RPS8 | ribosomal protein S8 | -0.053431 |
| ADM | adrenomedullin | -0.0524594 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0457971 |
| MT2A | metallothionein 2A | -0.045771 |
| RPL23 | ribosomal protein L23 | -0.0440608 |
| RPL37A | ribosomal protein L37a | -0.0436376 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0430457 |
| CALR | calreticulin | -0.0428182 |
| RPL35A | ribosomal protein L35a | -0.0424508 |
| RPLP1 | ribosomal protein, large, P1 | -0.0409103 |
| RPL12 | ribosomal protein L12 | -0.0392969 |
| RPS4X | ribosomal protein S4, X-linked | -0.0391139 |
| RPL11 | ribosomal protein L11 | -0.0390794 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0386018 |
| HLA-A | major histocompatibility complex, class I, A | -0.0375281 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0375182 |
| RPL13A | ribosomal protein L13a | -0.0367734 |
| RACK1 | receptor for activated C kinase 1 | -0.0367444 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.036523 |
| RPL26 | ribosomal protein L26 | -0.0364499 |
| PCBP2 | poly(rC) binding protein 2 | -0.036239 |
| YBX1 | Y box binding protein 1 | -0.0355355 |
| RPL36 | ribosomal protein L36 | -0.0346595 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0345672 |
| RPS19 | ribosomal protein S19 | -0.0345026 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0344466 |
| GNAS | GNAS complex locus | -0.0318928 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0313614 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0303313 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0300622 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0300165 |
| ANXA2 | annexin A2 | -0.030007 |
| RPS2 | ribosomal protein S2 | -0.0298501 |
| RPS13 | ribosomal protein S13 | -0.029728 |
| IER3 | immediate early response 3 | -0.0293334 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0287397 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0287334 |
| RPL19 | ribosomal protein L19 | -0.02872 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0283258 |
| PGK1 | phosphoglycerate kinase 1 | -0.0274194 |
| RPL9 | ribosomal protein L9 | -0.0271398 |
| RPLP2 | ribosomal protein, large, P2 | -0.0263009 |
| RPL5 | ribosomal protein L5 | -0.0249937 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0239451 |
| RPS27A | ribosomal protein S27a | -0.0237166 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0234289 |
| RPL37 | ribosomal protein L37 | -0.0228452 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0228369 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0227009 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0226985 |
| RPS17 | ribosomal protein S17 | -0.0221544 |
| LDHA | lactate dehydrogenase A | -0.0220333 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0219727 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0219076 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0219045 |
| RPL35 | ribosomal protein L35 | -0.0218327 |
| RPL31 | ribosomal protein L31 | -0.0216808 |
| RPL34 | ribosomal protein L34 | -0.0215768 |
| RPS23 | ribosomal protein S23 | -0.0214919 |
| WDR45B | WD repeat domain 45B | -0.0210236 |
| RPL8 | ribosomal protein L8 | -0.0208638 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0208205 |
| FAM162A | family with sequence similarity 162, member A | -0.0206304 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0206275 |
| RPL32 | ribosomal protein L32 | -0.0202122 |
| RPS14 | ribosomal protein S14 | -0.0201799 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0198135 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0195878 |
| RPS21 | ribosomal protein S21 | -0.0190559 |
| SEPTIN7 | septin 7 | -0.0188571 |
| WTAP | Wilms tumor 1 associated protein | -0.0186925 |
| PKM | pyruvate kinase, muscle | -0.0185303 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0183197 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0181818 |
| RPLP0 | ribosomal protein, large, P0 | -0.0181719 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0180676 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0180621 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0180561 |
| S100A9 | S100 calcium binding protein A9 | -0.0179815 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0179694 |
| RNF145 | ring finger protein 145 | -0.0178526 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.017815 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0176726 |
| HMGA1 | high mobility group AT-hook 1 | -0.0176703 |
| RPL18 | ribosomal protein L18 | -0.0174684 |
| RPL7 | ribosomal protein L7 | -0.0174445 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0173552 |
| RPL30 | ribosomal protein L30 | -0.0170876 |
