| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cinacalcet perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cinacalcet_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0968103 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0899444 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0637405 |
| LDHA | lactate dehydrogenase A | 0.061369 |
| VIM | vimentin | 0.0577276 |
| PCBP2 | poly(rC) binding protein 2 | 0.053087 |
| AFDN | afadin, adherens junction formation factor | 0.0519434 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0503291 |
| DNER | delta/notch-like EGF repeat containing | 0.0479281 |
| PDE8A | phosphodiesterase 8A | 0.045757 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0453003 |
| BSG | basigin (Ok blood group) | 0.043377 |
| FLNB | filamin B, beta | 0.0426995 |
| FLNA | filamin A, alpha | 0.0425149 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0396286 |
| SEC24A | SEC24 family member A | 0.0385878 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0385293 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0385258 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0382656 |
| ASPH | aspartate beta-hydroxylase | 0.0380819 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0368903 |
| CANX | calnexin | 0.0368145 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0366707 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0361476 |
| CAPRIN2 | caprin family member 2 | 0.0360865 |
| CCDC47 | coiled-coil domain containing 47 | 0.0356219 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 0.0355608 |
| FNIP1 | folliculin interacting protein 1 | 0.0355562 |
| EFNA5 | ephrin-A5 | 0.0352946 |
| HDLBP | high density lipoprotein binding protein | 0.0352377 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0345258 |
| SNX13 | sorting nexin 13 | 0.0344579 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0341472 |
| FAM193A | family with sequence similarity 193, member A | 0.0340412 |
| SCRN1 | secernin 1 | 0.0338026 |
| HLA-A | major histocompatibility complex, class I, A | 0.0331467 |
| PTMA | prothymosin, alpha | 0.0329921 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0326913 |
| EGFR | epidermal growth factor receptor | 0.0319131 |
| NAV2 | neuron navigator 2 | 0.0315174 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0311383 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0310794 |
| NDRG1 | N-myc downstream regulated 1 | 0.031039 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0308181 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0304558 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.029791 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0293821 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0293584 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.029224 |
| ITGB4 | integrin, beta 4 | 0.0289809 |
| ANXA2 | annexin A2 | 0.0284706 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0283067 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0282616 |
| KIAA1328 | KIAA1328 | 0.0280668 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0277202 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0275945 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | 0.0274828 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0274705 |
| DCP2 | decapping mRNA 2 | 0.0273878 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0273138 |
| SNX9 | sorting nexin 9 | 0.0271857 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0269738 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0268337 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0266634 |
| NPTN | neuroplastin | 0.0266359 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0264572 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0263524 |
| IDS | iduronate 2-sulfatase | 0.0262274 |
| EGR1 | early growth response 1 | 0.0262258 |
| SEC13 | SEC13 homolog (S. cerevisiae) | 0.0261022 |
| SETD5 | SET domain containing 5 | 0.0260944 |
| MCL1 | myeloid cell leukemia 1 | 0.0260844 |
| CALR | calreticulin | 0.0258878 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0257718 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0257662 |
| RPSA | ribosomal protein SA | 0.0256756 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0254618 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.025378 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0252758 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.0250265 |
| PSEN1 | presenilin 1 | 0.0249703 |
| SMAD3 | SMAD family member 3 | 0.0249577 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0248918 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0248312 |
| TMEM41B | transmembrane protein 41B | 0.02478 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0246982 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0246862 |
| TPM4 | tropomyosin 4 | 0.0243853 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.0242519 |
| HPS5 | Hermansky-Pudlak syndrome 5 | 0.0242439 |
| RNF111 | ring finger protein 111 | 0.0241818 |
| CUL5 | cullin 5 | 0.023892 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0237795 |
| COG6 | component of oligomeric golgi complex 6 | 0.023516 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0234793 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.0233722 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0233161 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0232169 |
| MSN | moesin | 0.0231417 |
| HJURP | Holliday junction recognition protein | 0.0231369 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.207228 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.109869 |
| CD44 | CD44 molecule (Indian blood group) | -0.0763123 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0715913 |
| DST | dystonin | -0.0710833 |
| GOLGA4 | golgin A4 | -0.0681931 |
| RBM39 | RNA binding motif protein 39 | -0.0629732 |
| SMYD3 | SET and MYND domain containing 3 | -0.0616675 |
| RDX | radixin | -0.0547794 |
| ANKRD11 | ankyrin repeat domain 11 | -0.052549 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.05239 |
| TPX2 | TPX2, microtubule-associated | -0.051738 |
| CENPF | centromere protein F, 350/400kDa | -0.0506905 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0484502 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0482868 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0467625 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0442281 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0439873 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0422679 |
| PHF20 | PHD finger protein 20 | -0.0421513 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0419134 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0413378 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.040934 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0409227 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.040616 |
| RRBP1 | ribosome binding protein 1 | -0.0405477 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0405173 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.039973 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0398753 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.039834 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0386997 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0386973 |
| ATM | ATM serine/threonine kinase | -0.0382836 |
| GOLGB1 | golgin B1 | -0.0377969 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | -0.0376159 |
| ZNF292 | zinc finger protein 292 | -0.0375445 |
| CEP170 | centrosomal protein 170kDa | -0.0368778 |
| YAP1 | Yes-associated protein 1 | -0.0367806 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0364881 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0363153 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0359814 |
| AHNAK | AHNAK nucleoprotein | -0.0358118 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0355625 |
| RTN4 | reticulon 4 | -0.0351387 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0351348 |
| SLC38A2 | solute carrier family 38, member 2 | -0.034755 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0343078 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.034262 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.034179 |
| RAD51B | RAD51 paralog B | -0.0341734 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0341703 |
| RAB33B | RAB33B, member RAS oncogene family | -0.0340972 |
| RIGI | RNA sensor RIG-I | -0.0337299 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0335197 |
| TXNRD1 | thioredoxin reductase 1 | -0.0333557 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0332469 |
| RPL36 | ribosomal protein L36 | -0.0331118 |
| RUNX1 | runt-related transcription factor 1 | -0.0329337 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0326501 |
| TMEM123 | transmembrane protein 123 | -0.0325296 |
| TFRC | transferrin receptor | -0.0323605 |
| SSH2 | slingshot protein phosphatase 2 | -0.0321382 |
| TCERG1 | transcription elongation regulator 1 | -0.0319689 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0317559 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0315905 |
| EXOC4 | exocyst complex component 4 | -0.0315697 |
| RPS17 | ribosomal protein S17 | -0.0315215 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0314487 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0306921 |
| RPL23 | ribosomal protein L23 | -0.0306885 |
| RPLP1 | ribosomal protein, large, P1 | -0.0306742 |
| DENND4A | DENN/MADD domain containing 4A | -0.0306493 |
| RSF1 | remodeling and spacing factor 1 | -0.0306404 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0305413 |
| RPS27A | ribosomal protein S27a | -0.0304397 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.030104 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0300731 |
| MT2A | metallothionein 2A | -0.0299531 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0295544 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0293483 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0293325 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0291972 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0291057 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0290949 |
| MYO10 | myosin X | -0.0289501 |
| RPL7 | ribosomal protein L7 | -0.0288986 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0287601 |
| IL6ST | interleukin 6 signal transducer | -0.0284988 |
| TXNIP | thioredoxin interacting protein | -0.0282679 |
| PRR11 | proline rich 11 | -0.0281868 |
| CEP350 | centrosomal protein 350kDa | -0.0280245 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0280219 |
| PTK2 | protein tyrosine kinase 2 | -0.0279338 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0277693 |
| ANO6 | anoctamin 6 | -0.0276538 |
| SEPTIN9 | septin 9 | -0.02761 |
| FBXO11 | F-box protein 11 | -0.0275591 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0275131 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0274823 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.027328 |
