| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cinacalcet perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cinacalcet_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.17127 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.160433 |
| FN1 | fibronectin 1 | 0.112116 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0971828 |
| CANX | calnexin | 0.0813162 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.075765 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0532931 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0475848 |
| RAI14 | retinoic acid induced 14 | 0.0445582 |
| STC2 | stanniocalcin 2 | 0.0437097 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0435454 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0372328 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0357912 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0357362 |
| SUCO | SUN domain containing ossification factor | 0.0346311 |
| TMSB4X | thymosin beta 4, X-linked | 0.0345469 |
| CD109 | CD109 molecule | 0.0345389 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0342491 |
| HDLBP | high density lipoprotein binding protein | 0.0340181 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0339304 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0328341 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0321907 |
| GLUL | glutamate-ammonia ligase | 0.0320893 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0313718 |
| VCL | vinculin | 0.0304584 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0300916 |
| SQSTM1 | sequestosome 1 | 0.0294947 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0292718 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0292708 |
| PCBP2 | poly(rC) binding protein 2 | 0.0287477 |
| CALR | calreticulin | 0.02776 |
| COPA | coatomer protein complex, subunit alpha | 0.0277127 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0272875 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0272071 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0264326 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0264157 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0263954 |
| PLIN2 | perilipin 2 | 0.0262126 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0257453 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0248225 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0244405 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0242708 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0242486 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0240576 |
| ATXN2 | ataxin 2 | 0.0238793 |
| WDR45B | WD repeat domain 45B | 0.0235402 |
| GRB10 | growth factor receptor-bound protein 10 | 0.023489 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0234659 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0228954 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0224769 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0223986 |
| KSR1 | kinase suppressor of ras 1 | 0.0223512 |
| RUNX2 | runt-related transcription factor 2 | 0.0222553 |
| SRP54 | signal recognition particle 54kDa | 0.0217387 |
| GANAB | glucosidase, alpha; neutral AB | 0.0213243 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0212424 |
| FAM193A | family with sequence similarity 193, member A | 0.0208119 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0205076 |
| GLG1 | golgi glycoprotein 1 | 0.0204736 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0204535 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0202851 |
| PGK1 | phosphoglycerate kinase 1 | 0.0202646 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0201574 |
| TPR | translocated promoter region, nuclear basket protein | 0.0201489 |
| COG5 | component of oligomeric golgi complex 5 | 0.019947 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0198969 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0198439 |
| USP3 | ubiquitin specific peptidase 3 | 0.0198292 |
| ADIPOR2 | adiponectin receptor 2 | 0.0197365 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0194698 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0194025 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0193482 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.019326 |
| FAM20C | family with sequence similarity 20, member C | 0.018965 |
| ARF1 | ADP-ribosylation factor 1 | 0.0188212 |
| VMP1 | vacuole membrane protein 1 | 0.0187186 |
| FNIP1 | folliculin interacting protein 1 | 0.018484 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | 0.0178898 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0178681 |
| FLNA | filamin A, alpha | 0.0178518 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0176223 |
| VEGFA | vascular endothelial growth factor A | 0.0173811 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0172603 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0172189 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0172145 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0170194 |
| PTGES2 | prostaglandin E synthase 2 | 0.0169058 |
| SAFB2 | scaffold attachment factor B2 | 0.0168853 |
| WDR43 | WD repeat domain 43 | 0.0168781 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0168362 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0163368 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.0163165 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0161815 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0159127 |
| PSEN1 | presenilin 1 | 0.0158105 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0157408 |
| CCDC47 | coiled-coil domain containing 47 | 0.0156349 |
| LOX | lysyl oxidase | 0.0156126 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0155718 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0155126 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.15952 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.145877 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.126561 |
| MT2A | metallothionein 2A | -0.11786 |
| ASPH | aspartate beta-hydroxylase | -0.0873278 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0831596 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0786488 |
| CENPF | centromere protein F, 350/400kDa | -0.0642293 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0609124 |
| RPS6 | ribosomal protein S6 | -0.0546913 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0524949 |
| B2M | beta-2-microglobulin | -0.04822 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0469755 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0466593 |
| RPS2 | ribosomal protein S2 | -0.0459456 |
| RPL37A | ribosomal protein L37a | -0.0424576 |
| RPL26 | ribosomal protein L26 | -0.0422523 |
| FTL | ferritin, light polypeptide | -0.0409373 |
| PTMA | prothymosin, alpha | -0.0406708 |
| MAP1B | microtubule-associated protein 1B | -0.0400065 |
| HMGA2 | high mobility group AT-hook 2 | -0.0396869 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0362191 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0353051 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0343801 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0336244 |
| RPL9 | ribosomal protein L9 | -0.0327556 |
| RPS12 | ribosomal protein S12 | -0.0310747 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0304672 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.030164 |
| PTK2 | protein tyrosine kinase 2 | -0.0296737 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0293264 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0290586 |
| SMYD3 | SET and MYND domain containing 3 | -0.0288387 |
| JMJD1C | jumonji domain containing 1C | -0.0285905 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0284932 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.027407 |
| RPL11 | ribosomal protein L11 | -0.0273184 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0270361 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0260853 |
| ATXN1 | ataxin 1 | -0.0260712 |
| SMAD3 | SMAD family member 3 | -0.0257177 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0255733 |
| RACK1 | receptor for activated C kinase 1 | -0.0252605 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0251738 |
| FOXP1 | forkhead box P1 | -0.0251712 |
| TMEM165 | transmembrane protein 165 | -0.0247578 |
| CD44 | CD44 molecule (Indian blood group) | -0.0247162 |
| RPL12 | ribosomal protein L12 | -0.0241627 |
| RBM39 | RNA binding motif protein 39 | -0.0237801 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0237786 |
| DUSP5 | dual specificity phosphatase 5 | -0.0235359 |
| RPL28 | ribosomal protein L28 | -0.0234285 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0233633 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0233591 |
| FHIT | fragile histidine triad | -0.0231491 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0226962 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0226092 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0225895 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.022554 |
| OSMR | oncostatin M receptor | -0.0225384 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0223519 |
| RPS19 | ribosomal protein S19 | -0.0222915 |
| RPL38 | ribosomal protein L38 | -0.0222319 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0221315 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0220985 |
| RPS8 | ribosomal protein S8 | -0.0220696 |
| PARD3 | par-3 family cell polarity regulator | -0.0218585 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0217238 |
| RPS3 | ribosomal protein S3 | -0.0216909 |
| RPS27 | ribosomal protein S27 | -0.0213952 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0213419 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0212632 |
| RPLP1 | ribosomal protein, large, P1 | -0.0211682 |
| EXOC4 | exocyst complex component 4 | -0.021099 |
| KIF5B | kinesin family member 5B | -0.0209013 |
| RPS27A | ribosomal protein S27a | -0.0208767 |
| RPS16 | ribosomal protein S16 | -0.0207347 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0207193 |
| IFI44L | interferon-induced protein 44-like | -0.0206296 |
| SPIDR | scaffolding protein involved in DNA repair | -0.020406 |
| PUM2 | pumilio RNA-binding family member 2 | -0.020376 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0203558 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0202055 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.020159 |
| FRY | furry homolog (Drosophila) | -0.0201401 |
| ETV6 | ets variant 6 | -0.0200766 |
| FNBP1 | formin binding protein 1 | -0.0200053 |
| SEPTIN9 | septin 9 | -0.0199653 |
| ZNF292 | zinc finger protein 292 | -0.0198342 |
| RPS23 | ribosomal protein S23 | -0.0197989 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0197168 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0196059 |
| ANLN | anillin, actin binding protein | -0.0194462 |
| AREG | amphiregulin | -0.0194309 |
| RPL21 | ribosomal protein L21 | -0.0191401 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0191333 |
| SLTM | SAFB-like, transcription modulator | -0.0191155 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0191074 |
| RPL18 | ribosomal protein L18 | -0.0188955 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0188483 |
