Ciprofloxacin Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively. (Chemical Entities of Biological Interest Ontology, CHEBI_100241)
External Link http://ctdbase.org/detail.go?type=chem&acc=D002939
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Genes

36 genes/proteins interacting with the chemical Ciprofloxacin from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCNB1 cyclin B1
CCNE1 cyclin E1
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHEK1 checkpoint kinase 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DHODH dihydroorotate dehydrogenase (quinone)
G6PD glucose-6-phosphate dehydrogenase
IFNG interferon, gamma
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL3 interleukin 3
IL4 interleukin 4
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP3 matrix metallopeptidase 3
NOD2 nucleotide-binding oligomerization domain containing 2
PARP1 poly (ADP-ribose) polymerase 1
PGD phosphogluconate dehydrogenase
PLK1 polo-like kinase 1
PON1 paraoxonase 1
TNF tumor necrosis factor
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa