Cisapride Gene Set

Dataset	HMDB Metabolites of Enzymes
Category	physical interactions
Type	metabolite
Description	The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere. (Chemical Entities of Biological Interest Ontology, CHEBI_3720)
External Link	http://www.hmdb.ca/metabolites/HMDB14742
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Genes

14 interacting proteins for the Cisapride metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol	Name
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR3A	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR4	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
KCNH2	potassium channel, voltage gated eag related subfamily H, member 2