| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0745762 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0542095 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0515589 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0477236 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0473371 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0456019 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0449883 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0440984 |
| RACK1 | receptor for activated C kinase 1 | 0.0424349 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.042095 |
| G0S2 | G0/G1 switch 2 | 0.0403717 |
| TPM3 | tropomyosin 3 | 0.0396477 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0395197 |
| FAT1 | FAT atypical cadherin 1 | 0.0394015 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0391515 |
| SMAD3 | SMAD family member 3 | 0.0383665 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0377513 |
| PLK2 | polo-like kinase 2 | 0.0365284 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0348606 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0346624 |
| FLNA | filamin A, alpha | 0.0345981 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.034459 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0325614 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0312263 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0310845 |
| RPL3 | ribosomal protein L3 | 0.0295605 |
| ARRDC3 | arrestin domain containing 3 | 0.0293387 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0289941 |
| SPAG9 | sperm associated antigen 9 | 0.0279139 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0278118 |
| CADM1 | cell adhesion molecule 1 | 0.025771 |
| WDR43 | WD repeat domain 43 | 0.025738 |
| SEPTIN9 | septin 9 | 0.0256767 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0251965 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0245796 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0245036 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.024069 |
| NRP2 | neuropilin 2 | 0.024001 |
| MSN | moesin | 0.0239599 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.023852 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.023507 |
| GOLGA4 | golgin A4 | 0.02344 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.023054 |
| ATP13A3 | ATPase type 13A3 | 0.0227304 |
| TFG | TRK-fused gene | 0.0226925 |
| COG5 | component of oligomeric golgi complex 5 | 0.022578 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0224943 |
| CTBP2 | C-terminal binding protein 2 | 0.0219786 |
| CRY1 | cryptochrome circadian clock 1 | 0.0217272 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.021683 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.021645 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0215947 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0214645 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0209438 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0207174 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0204392 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0203145 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.020244 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0201281 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0201021 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0199491 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0199261 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0197478 |
| NCKAP1 | NCK-associated protein 1 | 0.0195618 |
| NUP58 | nucleoporin 58 | 0.0194235 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0194051 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0193751 |
| IRS2 | insulin receptor substrate 2 | 0.0191201 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0189781 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0188966 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.0185228 |
| COPA | coatomer protein complex, subunit alpha | 0.0183741 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0181587 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0181127 |
| VEGFA | vascular endothelial growth factor A | 0.0180664 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0179942 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0179881 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0179515 |
| RUNX1 | runt-related transcription factor 1 | 0.0179435 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0172598 |
| PAX8 | paired box 8 | 0.0172563 |
| UBQLN1 | ubiquilin 1 | 0.0172543 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0171272 |
| PTK2 | protein tyrosine kinase 2 | 0.0169609 |
| RAB18 | RAB18, member RAS oncogene family | 0.0168185 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0168153 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0167836 |
| DENND2B | DENN domain containing 2B | 0.0167435 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.016536 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0165111 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0164037 |
| CCNL1 | cyclin L1 | 0.0163775 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0163735 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0163472 |
| SET | SET nuclear proto-oncogene | 0.0163282 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0162757 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0162686 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0162412 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0162217 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0161657 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.104653 |
| FRMD4A | FERM domain containing 4A | -0.0952541 |
| TMSB10 | thymosin beta 10 | -0.0943658 |
| HLA-B | major histocompatibility complex, class I, B | -0.0844884 |
| ASPH | aspartate beta-hydroxylase | -0.0779601 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0683745 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0635912 |
| CP | ceruloplasmin (ferroxidase) | -0.0635816 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0609644 |
| MT2A | metallothionein 2A | -0.0564433 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0549169 |
| FTL | ferritin, light polypeptide | -0.0518772 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0468295 |
| RRBP1 | ribosome binding protein 1 | -0.0454855 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0439197 |
| APOL1 | apolipoprotein L, 1 | -0.036053 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0337884 |
| CTSD | cathepsin D | -0.033356 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0329919 |
| RPS24 | ribosomal protein S24 | -0.0328528 |
| CA12 | carbonic anhydrase XII | -0.0320156 |
| HLA-C | major histocompatibility complex, class I, C | -0.0318158 |
| CAVIN1 | caveolae associated protein 1 | -0.0313962 |
| RPS6 | ribosomal protein S6 | -0.0311445 |
| RPL35A | ribosomal protein L35a | -0.0292777 |
| RPL28 | ribosomal protein L28 | -0.0284653 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0281862 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0264162 |
| S100A6 | S100 calcium binding protein A6 | -0.0257723 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0242588 |
| RPLP2 | ribosomal protein, large, P2 | -0.0241834 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0241621 |
| RPLP1 | ribosomal protein, large, P1 | -0.0237483 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0237331 |
| RPL34 | ribosomal protein L34 | -0.0234469 |
| RAI14 | retinoic acid induced 14 | -0.0234409 |
| RPL31 | ribosomal protein L31 | -0.0232927 |
| HLA-E | major histocompatibility complex, class I, E | -0.0231581 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0227874 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0226652 |
| LMNA | lamin A/C | -0.0226059 |
| RPL38 | ribosomal protein L38 | -0.0224843 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0224164 |
| RTN4 | reticulon 4 | -0.0221919 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0221816 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0221678 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0219632 |
| S100A10 | S100 calcium binding protein A10 | -0.0218918 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0215152 |
| ANXA2 | annexin A2 | -0.0211047 |
| RIGI | RNA sensor RIG-I | -0.0208756 |
| PTMA | prothymosin, alpha | -0.0207334 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0207305 |
| RPS21 | ribosomal protein S21 | -0.0206966 |
| CLMP | CXADR-like membrane protein | -0.0202336 |
| ANXA4 | annexin A4 | -0.0200585 |
| PLIN2 | perilipin 2 | -0.0198746 |
| HMGB1 | high mobility group box 1 | -0.019238 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0192037 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0191073 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0190036 |
| GNAS | GNAS complex locus | -0.0188661 |
| RPL7A | ribosomal protein L7a | -0.0186778 |
| ACTG1 | actin gamma 1 | -0.0186263 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0186193 |
| CD82 | CD82 molecule | -0.0185013 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0184317 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0183184 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0182334 |
| RPL37A | ribosomal protein L37a | -0.0182201 |
| CD44 | CD44 molecule (Indian blood group) | -0.0181512 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0179573 |
| MT1X | metallothionein 1X | -0.0179461 |
| RPS27A | ribosomal protein S27a | -0.017833 |
| PXDN | peroxidasin | -0.0177832 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0177461 |
| FKBP5 | FK506 binding protein 5 | -0.0175533 |
| MMP7 | matrix metallopeptidase 7 | -0.0174004 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0172914 |
| RPS19 | ribosomal protein S19 | -0.0170622 |
| MTDH | metadherin | -0.016847 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0163601 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.01634 |
| BNC2 | basonuclin 2 | -0.016151 |
| AHNAK | AHNAK nucleoprotein | -0.0161389 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0159828 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.015901 |
| RPL12 | ribosomal protein L12 | -0.0157722 |
| S100A11 | S100 calcium binding protein A11 | -0.0156912 |
| EHBP1 | EH domain binding protein 1 | -0.0156813 |
| TPM1 | tropomyosin 1 (alpha) | -0.0155716 |
| RPS8 | ribosomal protein S8 | -0.0155441 |
| TMEM263 | transmembrane protein 263 | -0.0154897 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0153274 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0149455 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0149434 |
| ARF1 | ADP-ribosylation factor 1 | -0.0149026 |
| RPLP0 | ribosomal protein, large, P0 | -0.0148616 |
| DIAPH2 | diaphanous-related formin 2 | -0.0148544 |
| TSC22D3 | TSC22 domain family, member 3 | -0.0145474 |
