| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.172822 |
| RACK1 | receptor for activated C kinase 1 | 0.0500973 |
| VCL | vinculin | 0.0484743 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0417244 |
| EFNA5 | ephrin-A5 | 0.0404773 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0395015 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0358479 |
| NDRG1 | N-myc downstream regulated 1 | 0.0327276 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0298412 |
| EGFR | epidermal growth factor receptor | 0.0275824 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.0261882 |
| INTS6 | integrator complex subunit 6 | 0.0261534 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0259771 |
| AUTS2 | autism susceptibility candidate 2 | 0.0249207 |
| TNS1 | tensin 1 | 0.0245973 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0242421 |
| AADAC | arylacetamide deacetylase | 0.0239113 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0233966 |
| EGR1 | early growth response 1 | 0.0232448 |
| HMGA2 | high mobility group AT-hook 2 | 0.0222241 |
| RHCG | Rh family, C glycoprotein | 0.0219015 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0218925 |
| SP100 | SP100 nuclear antigen | 0.0213008 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0202816 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0182737 |
| DAPK1 | death-associated protein kinase 1 | 0.0179643 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0178753 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0169828 |
| SLC25A51 | solute carrier family 25, member 51 | 0.0167499 |
| LMO7 | LIM domain 7 | 0.0165328 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0164671 |
| VEGFA | vascular endothelial growth factor A | 0.0163239 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0159786 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0153495 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0153292 |
| NTN4 | netrin 4 | 0.0153247 |
| DSPP | dentin sialophosphoprotein | 0.0152944 |
| RPS15A | ribosomal protein S15a | 0.0147947 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.0136932 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0135224 |
| RCOR1 | REST corepressor 1 | 0.0133168 |
| ATXN1 | ataxin 1 | 0.013222 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0131701 |
| FN1 | fibronectin 1 | 0.0130433 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.01231 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0120896 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0120128 |
| RPL35A | ribosomal protein L35a | 0.011978 |
| CDKL5 | cyclin-dependent kinase-like 5 | 0.0116027 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0115857 |
| PRKCA | protein kinase C, alpha | 0.0114176 |
| CCDC88A | coiled-coil domain containing 88A | 0.0112655 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.0112235 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.011159 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0111421 |
| PGM3 | phosphoglucomutase 3 | 0.0110716 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0106721 |
| SERF2 | small EDRK-rich factor 2 | 0.0106548 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0104874 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0103831 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0103686 |
| MAP7 | microtubule-associated protein 7 | 0.0103448 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0101941 |
| NABP1 | nucleic acid binding protein 1 | 0.0101347 |
| RNF213 | ring finger protein 213 | 0.0100963 |
| BICC1 | BicC family RNA binding protein 1 | 0.0099901 |
| IGSF11 | immunoglobulin superfamily, member 11 | 0.00991544 |
| GRB10 | growth factor receptor-bound protein 10 | 0.00988 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.00981568 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0097391 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00967729 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00965621 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00959323 |
| RAD51B | RAD51 paralog B | 0.00937771 |
| TLE4 | transducin-like enhancer of split 4 | 0.00936778 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00936227 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00929166 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.00926604 |
| CREBBP | CREB binding protein | 0.00924984 |
| EXOSC3 | exosome component 3 | 0.00917282 |
| RND3 | Rho family GTPase 3 | 0.00893614 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00875513 |
| CUX1 | cut-like homeobox 1 | 0.00874932 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00870249 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.00851081 |
| LOXL2 | lysyl oxidase-like 2 | 0.00845689 |
| NCKAP5 | NCK-associated protein 5 | 0.00832753 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00826753 |
| BMP6 | bone morphogenetic protein 6 | 0.00825827 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.00814668 |
| PALLD | palladin, cytoskeletal associated protein | 0.00812673 |
| ANXA3 | annexin A3 | 0.0079329 |
| FERMT2 | fermitin family member 2 | 0.00788217 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.00784816 |
| USP53 | ubiquitin specific peptidase 53 | 0.0078464 |
| HPCAL1 | hippocalcin-like 1 | 0.00780514 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0078014 |
| CLMP | CXADR-like membrane protein | 0.00771444 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.00771165 |
| KRT86 | keratin 86, type II | 0.00767241 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.253117 |
| UBC | ubiquitin C | -0.181581 |
| VIM | vimentin | -0.167799 |
| RPS27A | ribosomal protein S27a | -0.121051 |
| TMSB10 | thymosin beta 10 | -0.11837 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.112322 |
| TXNRD1 | thioredoxin reductase 1 | -0.0935638 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0919567 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0902316 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0888157 |
| SMAD3 | SMAD family member 3 | -0.0886515 |
| AHNAK | AHNAK nucleoprotein | -0.0883353 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.084162 |
| ACTG1 | actin gamma 1 | -0.0783655 |
| ANXA2 | annexin A2 | -0.0767727 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0754374 |
| MT2A | metallothionein 2A | -0.0746018 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0728142 |
| CA12 | carbonic anhydrase XII | -0.0686243 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0681408 |
| PCBP2 | poly(rC) binding protein 2 | -0.0652492 |
| MT1X | metallothionein 1X | -0.0640663 |
| FAM107B | family with sequence similarity 107, member B | -0.0638453 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0637214 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0623463 |
| ASPH | aspartate beta-hydroxylase | -0.0620596 |
| PKM | pyruvate kinase, muscle | -0.0604444 |
| ENO1 | enolase 1, (alpha) | -0.0594133 |
| PTMA | prothymosin, alpha | -0.0542093 |
| RPS16 | ribosomal protein S16 | -0.0539167 |
| FLNB | filamin B, beta | -0.0531382 |
| LDHA | lactate dehydrogenase A | -0.0512279 |
| RTN4 | reticulon 4 | -0.0501201 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0495024 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0492195 |
| FTL | ferritin, light polypeptide | -0.0473254 |
| CMIP | c-Maf inducing protein | -0.0469057 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0463071 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0462915 |
| RPS24 | ribosomal protein S24 | -0.0459228 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0455781 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0455234 |
| ACTN4 | actinin, alpha 4 | -0.0414205 |
| CANX | calnexin | -0.0410627 |
| CD44 | CD44 molecule (Indian blood group) | -0.0406393 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0391985 |
| KRT7 | keratin 7, type II | -0.0391007 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0390959 |
| RPL28 | ribosomal protein L28 | -0.038575 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0383869 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0382823 |
| SPAG9 | sperm associated antigen 9 | -0.0382309 |
| AXL | AXL receptor tyrosine kinase | -0.0377352 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0377213 |
| OGA | O-GlcNAcase | -0.037675 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0372702 |
| APP | amyloid beta (A4) precursor protein | -0.0364737 |
| KYNU | kynureninase | -0.0364066 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0360606 |
| RPS6 | ribosomal protein S6 | -0.0360264 |
| S100A6 | S100 calcium binding protein A6 | -0.0356635 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0354874 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0351545 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0344518 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0344328 |
| KRT81 | keratin 81, type II | -0.0343827 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0343764 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0342205 |
| RPL4 | ribosomal protein L4 | -0.034081 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0340634 |
| USP34 | ubiquitin specific peptidase 34 | -0.0338216 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0323708 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0312979 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0311972 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0311537 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0310273 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0306356 |
| RPL23 | ribosomal protein L23 | -0.0305281 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0301984 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0301551 |
| SMYD3 | SET and MYND domain containing 3 | -0.0300061 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0299113 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0298748 |
| CA8 | carbonic anhydrase VIII | -0.0297899 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0297393 |
| GRAMD1B | GRAM domain containing 1B | -0.0296534 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0291811 |
| S100A10 | S100 calcium binding protein A10 | -0.0290805 |
| RPS3 | ribosomal protein S3 | -0.029045 |
| RPS19 | ribosomal protein S19 | -0.0288045 |
| VMP1 | vacuole membrane protein 1 | -0.0286556 |
| STC1 | stanniocalcin 1 | -0.028644 |
| RPS5 | ribosomal protein S5 | -0.0282988 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0282924 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0282484 |
| NAV2 | neuron navigator 2 | -0.0281658 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0279153 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.027478 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0273855 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0273754 |
