| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.0451937 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0435245 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0403236 |
| EGFR | epidermal growth factor receptor | 0.037677 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0335461 |
| VCL | vinculin | 0.0333707 |
| SMAD3 | SMAD family member 3 | 0.0313234 |
| ITGA6 | integrin, alpha 6 | 0.0279879 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0258447 |
| EFNA5 | ephrin-A5 | 0.025844 |
| PLEC | plectin | 0.0251014 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.022791 |
| LMO7 | LIM domain 7 | 0.0221483 |
| MYOF | myoferlin | 0.022114 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0216864 |
| CORO1C | coronin, actin binding protein, 1C | 0.0212927 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0210851 |
| EZR | ezrin | 0.0202185 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0200784 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.019697 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0188242 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0187663 |
| FOXO1 | forkhead box O1 | 0.0186648 |
| BCL2L1 | BCL2-like 1 | 0.0185461 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0185024 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0181942 |
| ERBIN | erbb2 interacting protein | 0.0175934 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0172293 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0169736 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0168967 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0168022 |
| WWC1 | WW and C2 domain containing 1 | 0.0166976 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0163118 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0161972 |
| DSCAM | Down syndrome cell adhesion molecule | 0.015929 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0158683 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0157846 |
| STK39 | serine threonine kinase 39 | 0.0154688 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0154586 |
| DST | dystonin | 0.0153723 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0151182 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0150238 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0149146 |
| SERTAD2 | SERTA domain containing 2 | 0.0148206 |
| VCAN | versican | 0.0147289 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0146942 |
| SEPTIN9 | septin 9 | 0.0145195 |
| LAMA4 | laminin, alpha 4 | 0.0145175 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0142604 |
| CAPRIN2 | caprin family member 2 | 0.0142246 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0141333 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0140365 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0138108 |
| DSPP | dentin sialophosphoprotein | 0.0137301 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0135508 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0135367 |
| ANXA11 | annexin A11 | 0.0134785 |
| CAB39 | calcium binding protein 39 | 0.0134136 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0133955 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0133882 |
| RACK1 | receptor for activated C kinase 1 | 0.0133717 |
| JMJD1C | jumonji domain containing 1C | 0.0131871 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0131197 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0125091 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0121754 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0120816 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0119738 |
| TJP1 | tight junction protein 1 | 0.0116539 |
| RASAL2 | RAS protein activator like 2 | 0.0115265 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.011301 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0111732 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.011138 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.010974 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0107297 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0106556 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.010651 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0105091 |
| NEK7 | NIMA-related kinase 7 | 0.010502 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0104762 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0104478 |
| ANO6 | anoctamin 6 | 0.0103295 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.010292 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.010268 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0102453 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0102317 |
| FOXO3 | forkhead box O3 | 0.0100098 |
| SGMS2 | sphingomyelin synthase 2 | 0.0099933 |
| KIAA0040 | KIAA0040 | 0.00995999 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00992065 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00988907 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00987313 |
| MED13L | mediator complex subunit 13-like | 0.0098705 |
| PRELID2 | PRELI domain containing 2 | 0.00985375 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.00981838 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.00971083 |
| ARRDC3 | arrestin domain containing 3 | 0.00959335 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.00952502 |
| NPTN | neuroplastin | 0.00950963 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0094549 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.00940138 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.119823 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0671717 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0647351 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0570605 |
| FTL | ferritin, light polypeptide | -0.0560434 |
| PTMA | prothymosin, alpha | -0.053893 |
| VIM | vimentin | -0.0507169 |
| HMGA1 | high mobility group AT-hook 1 | -0.0472745 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0408699 |
| KLK10 | kallikrein-related peptidase 10 | -0.0393435 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.036742 |
| RPL35A | ribosomal protein L35a | -0.0343024 |
| LAMB3 | laminin, beta 3 | -0.033017 |
| ACTG1 | actin gamma 1 | -0.0317174 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0303943 |
| RPL31 | ribosomal protein L31 | -0.0300259 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0299295 |
| RPL37A | ribosomal protein L37a | -0.0294471 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0292929 |
| TXNIP | thioredoxin interacting protein | -0.0291604 |
| RPS8 | ribosomal protein S8 | -0.0289956 |
| POTEF | POTE ankyrin domain family, member F | -0.0283752 |
| S100A10 | S100 calcium binding protein A10 | -0.0278645 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0277764 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0276489 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0257917 |
| MXD1 | MAX dimerization protein 1 | -0.0256405 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0250056 |
| B2M | beta-2-microglobulin | -0.024465 |
| RPS13 | ribosomal protein S13 | -0.0236392 |
| RPS6 | ribosomal protein S6 | -0.0234744 |
| EGR1 | early growth response 1 | -0.0234546 |
| RPLP2 | ribosomal protein, large, P2 | -0.0230076 |
| RPLP1 | ribosomal protein, large, P1 | -0.0224365 |
| CLMP | CXADR-like membrane protein | -0.0223206 |
| S100A6 | S100 calcium binding protein A6 | -0.0218254 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0215992 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0215955 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0215393 |
| RPS27A | ribosomal protein S27a | -0.0209701 |
| RPS24 | ribosomal protein S24 | -0.0208182 |
| RPS21 | ribosomal protein S21 | -0.0205868 |
| S100A11 | S100 calcium binding protein A11 | -0.0203173 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0197757 |
| RPL9 | ribosomal protein L9 | -0.0196073 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.01951 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0193571 |
| RPS23 | ribosomal protein S23 | -0.0191754 |
| ANXA2 | annexin A2 | -0.0189311 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0187148 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0185787 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0184342 |
| RIOK3 | RIO kinase 3 | -0.0181967 |
| RPS29 | ribosomal protein S29 | -0.0181282 |
| RPS3 | ribosomal protein S3 | -0.0179659 |
| RPS16 | ribosomal protein S16 | -0.0174929 |
| PGK1 | phosphoglycerate kinase 1 | -0.0172372 |
| RPS25 | ribosomal protein S25 | -0.0171186 |
| RPL34 | ribosomal protein L34 | -0.0170265 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.016761 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.016549 |
| RPL8 | ribosomal protein L8 | -0.0162738 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0161893 |
| RPL28 | ribosomal protein L28 | -0.0160176 |
| RPL11 | ribosomal protein L11 | -0.0158566 |
| LDHA | lactate dehydrogenase A | -0.0154538 |
| SQSTM1 | sequestosome 1 | -0.0154494 |
| RPS20 | ribosomal protein S20 | -0.0152286 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0152243 |
| FOSL1 | FOS-like antigen 1 | -0.015221 |
| RPL12 | ribosomal protein L12 | -0.014948 |
| RPL37 | ribosomal protein L37 | -0.0147446 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0147381 |
| RPS15 | ribosomal protein S15 | -0.0145824 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0145447 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0141952 |
| NDRG1 | N-myc downstream regulated 1 | -0.0141698 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0138946 |
| GNAS | GNAS complex locus | -0.0137011 |
| RPS19 | ribosomal protein S19 | -0.0136309 |
| HLA-A | major histocompatibility complex, class I, A | -0.0136247 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0135635 |
| RPL30 | ribosomal protein L30 | -0.0134659 |
| TPM4 | tropomyosin 4 | -0.0133733 |
| RPL7A | ribosomal protein L7a | -0.0133153 |
| IER3 | immediate early response 3 | -0.0132554 |
| RPS27 | ribosomal protein S27 | -0.0129311 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0127694 |
| UPP1 | uridine phosphorylase 1 | -0.0126898 |
| MCL1 | myeloid cell leukemia 1 | -0.0125932 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0125635 |
| MORF4L2 | mortality factor 4 like 2 | -0.0125413 |
| NOP58 | NOP58 ribonucleoprotein | -0.0124641 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0124446 |
| RPL38 | ribosomal protein L38 | -0.0124052 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0123669 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0123502 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0122878 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0122113 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0121569 |