| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.211394 |
| NDRG1 | N-myc downstream regulated 1 | 0.132295 |
| CD109 | CD109 molecule | 0.10032 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0779957 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0742915 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0530859 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0456317 |
| CCNL1 | cyclin L1 | 0.0450003 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0403723 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0403012 |
| NRCAM | neuronal cell adhesion molecule | 0.0401085 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0400555 |
| NUP58 | nucleoporin 58 | 0.0393789 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0370078 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0341038 |
| FKBP5 | FK506 binding protein 5 | 0.0317711 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0315332 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0315157 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0308138 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0289208 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0288939 |
| ADM | adrenomedullin | 0.0288019 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.028505 |
| RNF145 | ring finger protein 145 | 0.0268813 |
| PER1 | period circadian clock 1 | 0.0255918 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0250816 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0244947 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0240003 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0238017 |
| PTCHD4 | patched domain containing 4 | 0.0237595 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0236037 |
| EMP1 | epithelial membrane protein 1 | 0.0235461 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0235297 |
| VEGFA | vascular endothelial growth factor A | 0.023354 |
| RACK1 | receptor for activated C kinase 1 | 0.0232071 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0230975 |
| HELZ | helicase with zinc finger | 0.0230232 |
| VGF | VGF nerve growth factor inducible | 0.0229813 |
| PDE10A | phosphodiesterase 10A | 0.0226733 |
| SEC24A | SEC24 family member A | 0.0226387 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.022578 |
| CALD1 | caldesmon 1 | 0.0225401 |
| EGR1 | early growth response 1 | 0.0224125 |
| RPL3 | ribosomal protein L3 | 0.0222593 |
| USP53 | ubiquitin specific peptidase 53 | 0.022203 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.022073 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0218703 |
| TFRC | transferrin receptor | 0.0217785 |
| IRS2 | insulin receptor substrate 2 | 0.0217544 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0215807 |
| TPR | translocated promoter region, nuclear basket protein | 0.0213258 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0212668 |
| GDF15 | growth differentiation factor 15 | 0.0211624 |
| CDC73 | cell division cycle 73 | 0.0209946 |
| CABIN1 | calcineurin binding protein 1 | 0.0209301 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0208835 |
| MCL1 | myeloid cell leukemia 1 | 0.0207323 |
| RBM39 | RNA binding motif protein 39 | 0.0205626 |
| USP37 | ubiquitin specific peptidase 37 | 0.0203075 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0202518 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0201548 |
| WDR43 | WD repeat domain 43 | 0.0200339 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0199376 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0195248 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0195214 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.019519 |
| A2M | alpha-2-macroglobulin | 0.0192827 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0191197 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0189471 |
| DENND1A | DENN/MADD domain containing 1A | 0.018943 |
| MT2A | metallothionein 2A | 0.0186735 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0185707 |
| MKRN1 | makorin ring finger protein 1 | 0.018442 |
| RLF | rearranged L-myc fusion | 0.0183905 |
| STXBP1 | syntaxin binding protein 1 | 0.0179899 |
| LRRC23 | leucine rich repeat containing 23 | 0.0176875 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0176857 |
| ANKRD11 | ankyrin repeat domain 11 | 0.017533 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0175319 |
| STRIP2 | striatin interacting protein 2 | 0.0174289 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0172647 |
| SYNM | synemin, intermediate filament protein | 0.0171109 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0171031 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0170002 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0167322 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0167309 |
| IGF2 | insulin-like growth factor 2 | 0.0164726 |
| GSN | gelsolin | 0.0162395 |
| AFDN | afadin, adherens junction formation factor | 0.016096 |
| EZR | ezrin | 0.0160061 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0159671 |
| COPA | coatomer protein complex, subunit alpha | 0.0158639 |
| FNDC3A | fibronectin type III domain containing 3A | 0.015715 |
| RIOK3 | RIO kinase 3 | 0.0156699 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0155279 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0154867 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.01537 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0151158 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0151057 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0149096 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.505566 |
| VIM | vimentin | -0.281933 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.204777 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.132675 |
| UBC | ubiquitin C | -0.112295 |
| ASPH | aspartate beta-hydroxylase | -0.0966849 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0892868 |
| S100A6 | S100 calcium binding protein A6 | -0.0823675 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0820749 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0730779 |
| ENO1 | enolase 1, (alpha) | -0.0726882 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0614981 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0584626 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0580544 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0578551 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0553509 |
| TMSB10 | thymosin beta 10 | -0.0546516 |
| ACTG1 | actin gamma 1 | -0.0539979 |
| AHNAK | AHNAK nucleoprotein | -0.0529181 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0514518 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0477114 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0476288 |
| PKM | pyruvate kinase, muscle | -0.0462979 |
| IER3 | immediate early response 3 | -0.0440543 |
| FMN1 | formin 1 | -0.0440496 |
| RTN4 | reticulon 4 | -0.0410436 |
| PTMA | prothymosin, alpha | -0.0400728 |
| TNNC1 | troponin C type 1 (slow) | -0.0390589 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0382061 |
| FRMD4A | FERM domain containing 4A | -0.038111 |
| GSK3B | glycogen synthase kinase 3 beta | -0.037671 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.035914 |
| COG5 | component of oligomeric golgi complex 5 | -0.0349892 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0349477 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0348807 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0345839 |
| SDC2 | syndecan 2 | -0.034528 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0343681 |
| GPC6 | glypican 6 | -0.033614 |
| RPS27A | ribosomal protein S27a | -0.0334506 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0334505 |
| TAGLN2 | transgelin 2 | -0.0332982 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0332152 |
| PCDH7 | protocadherin 7 | -0.0331032 |
| NAV1 | neuron navigator 1 | -0.0329837 |
| NLGN1 | neuroligin 1 | -0.0326385 |
| HLA-B | major histocompatibility complex, class I, B | -0.0326105 |
| RHEB | Ras homolog enriched in brain | -0.0321216 |
| SRPK2 | SRSF protein kinase 2 | -0.0320909 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0317804 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0314827 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0314292 |
| RPLP1 | ribosomal protein, large, P1 | -0.030783 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0305054 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0304657 |
| FMNL2 | formin-like 2 | -0.030304 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0301827 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0299953 |
| ACTN4 | actinin, alpha 4 | -0.0299916 |
| APP | amyloid beta (A4) precursor protein | -0.0294587 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0294382 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0290903 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0290444 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0286169 |
| MYO10 | myosin X | -0.0285501 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0283565 |
| POTEF | POTE ankyrin domain family, member F | -0.0280931 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | -0.0279812 |
| LDHA | lactate dehydrogenase A | -0.0275962 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0274372 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.026113 |
| DUSP6 | dual specificity phosphatase 6 | -0.0260763 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0250987 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.0250744 |
| SMYD3 | SET and MYND domain containing 3 | -0.0248552 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0246377 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0245026 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0244092 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0241382 |
| S100A9 | S100 calcium binding protein A9 | -0.0240883 |
| S100A10 | S100 calcium binding protein A10 | -0.0238868 |
| FNDC3B | fibronectin type III domain containing 3B | -0.023648 |
| PCBP2 | poly(rC) binding protein 2 | -0.0235611 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0227712 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0226588 |
| CALU | calumenin | -0.0224373 |
| AHR | aryl hydrocarbon receptor | -0.0223687 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0223221 |
| MTPN | myotrophin | -0.022255 |
| RPLP2 | ribosomal protein, large, P2 | -0.0221263 |
| ZYX | zyxin | -0.0220943 |
| MITF | microphthalmia-associated transcription factor | -0.0218665 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0217725 |
| RUNX1 | runt-related transcription factor 1 | -0.0215346 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0214831 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0210992 |
| MACROD2 | MACRO domain containing 2 | -0.0210141 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0208576 |
| PRELID2 | PRELI domain containing 2 | -0.0208157 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0205922 |