| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.0774717 |
| ASPH | aspartate beta-hydroxylase | 0.0649143 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.063988 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0632657 |
| PRELID2 | PRELI domain containing 2 | 0.0590473 |
| PAX8 | paired box 8 | 0.0548043 |
| SVIL | supervillin | 0.0535802 |
| RACK1 | receptor for activated C kinase 1 | 0.0535523 |
| FLNA | filamin A, alpha | 0.0501721 |
| RAD51B | RAD51 paralog B | 0.0484335 |
| CD44 | CD44 molecule (Indian blood group) | 0.0475343 |
| MKI67 | marker of proliferation Ki-67 | 0.046243 |
| DIAPH3 | diaphanous-related formin 3 | 0.0449622 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0448562 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0432095 |
| HMGA2 | high mobility group AT-hook 2 | 0.0428142 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0422439 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0414151 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0409769 |
| VCL | vinculin | 0.0394814 |
| EGFR | epidermal growth factor receptor | 0.0394385 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0385112 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0379996 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0374485 |
| LAMC2 | laminin, gamma 2 | 0.0372869 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0366485 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0364788 |
| WWC1 | WW and C2 domain containing 1 | 0.0356348 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0342785 |
| SMYD3 | SET and MYND domain containing 3 | 0.0341861 |
| SEPTIN9 | septin 9 | 0.0338036 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0316296 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0289406 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0285677 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0285403 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0285319 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0281783 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0279281 |
| FHIT | fragile histidine triad | 0.0277041 |
| ANO6 | anoctamin 6 | 0.0274383 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0264892 |
| NF1 | neurofibromin 1 | 0.0260786 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.02604 |
| PTK2 | protein tyrosine kinase 2 | 0.0256319 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0254157 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.025219 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0247436 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0247036 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0246903 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0243835 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0243686 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0242453 |
| PDGFC | platelet derived growth factor C | 0.0240174 |
| EHBP1 | EH domain binding protein 1 | 0.0238395 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0231891 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0230975 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0229357 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0227193 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0224659 |
| PLEC | plectin | 0.0224343 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0222806 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0222352 |
| CCDC138 | coiled-coil domain containing 138 | 0.0220752 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0216715 |
| AEBP2 | AE binding protein 2 | 0.0216662 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0214438 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0213622 |
| RPS12 | ribosomal protein S12 | 0.0213598 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0211733 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0210632 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0209736 |
| ERBIN | erbb2 interacting protein | 0.0209511 |
| GPR39 | G protein-coupled receptor 39 | 0.0209394 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0207149 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0206447 |
| MTAP | methylthioadenosine phosphorylase | 0.0204451 |
| RPL3 | ribosomal protein L3 | 0.0204101 |
| ATG7 | autophagy related 7 | 0.0203672 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0202324 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.020105 |
| GPATCH8 | G patch domain containing 8 | 0.02 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0199906 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0199785 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0197874 |
| MMS22L | MMS22-like, DNA repair protein | 0.0196982 |
| MACROH2A1 | macroH2A.1 histone | 0.0196754 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0193355 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0192038 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0189824 |
| PCED1B | PC-esterase domain containing 1B | 0.0187563 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0186445 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0182713 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0181462 |
| ATXN7 | ataxin 7 | 0.0179282 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0178943 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0178301 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.017815 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0178102 |
| GPATCH2L | G patch domain containing 2-like | 0.0177011 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0176878 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0955008 |
| ANXA1 | annexin A1 | -0.0483837 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0436533 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0427974 |
| NDRG1 | N-myc downstream regulated 1 | -0.0416441 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.041199 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.040411 |
| EGR1 | early growth response 1 | -0.0402986 |
| PGK1 | phosphoglycerate kinase 1 | -0.038845 |
| EREG | epiregulin | -0.0352359 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0344786 |
| PTMA | prothymosin, alpha | -0.0340671 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.033671 |
| LDHA | lactate dehydrogenase A | -0.0328215 |
| SQSTM1 | sequestosome 1 | -0.0327409 |
| CANX | calnexin | -0.0323906 |
| APP | amyloid beta (A4) precursor protein | -0.0323158 |
| CCND1 | cyclin D1 | -0.0316784 |
| FTL | ferritin, light polypeptide | -0.03033 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0299869 |
| TMSB4X | thymosin beta 4, X-linked | -0.0294104 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0289889 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0284314 |
| EZR | ezrin | -0.0275872 |
| TES | testin LIM domain protein | -0.0262926 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0253453 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.024904 |
| MATR3 | matrin 3 | -0.0239476 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0238286 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0237709 |
| PKM | pyruvate kinase, muscle | -0.0237436 |
| RBM39 | RNA binding motif protein 39 | -0.0235217 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0227179 |
| WDR45B | WD repeat domain 45B | -0.0225722 |
| ZNF292 | zinc finger protein 292 | -0.0220138 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0218237 |
| FOSL1 | FOS-like antigen 1 | -0.0217171 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0215611 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.0212575 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0212245 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0209023 |
| H1-0 | H1.0 linker histone | -0.0207448 |
| RLF | rearranged L-myc fusion | -0.0205582 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0201177 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.019659 |
| DSTN | destrin (actin depolymerizing factor) | -0.0196267 |
| EMP1 | epithelial membrane protein 1 | -0.0196091 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.019583 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0194516 |
| TXNRD1 | thioredoxin reductase 1 | -0.0192896 |
| ENO1 | enolase 1, (alpha) | -0.0191509 |
| DUSP5 | dual specificity phosphatase 5 | -0.0190899 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0189829 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0188144 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0187707 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0184715 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0184154 |
| MLF1 | myeloid leukemia factor 1 | -0.0182723 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0182181 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0181827 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0181582 |
| IER3 | immediate early response 3 | -0.0176936 |
| UPP1 | uridine phosphorylase 1 | -0.0176756 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0176173 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0176084 |
| SEPTIN7 | septin 7 | -0.0174194 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0170726 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0170288 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0169588 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.016708 |
| AZIN1 | antizyme inhibitor 1 | -0.0166721 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0166254 |
| BRD2 | bromodomain containing 2 | -0.0164752 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0164101 |
| KRT7 | keratin 7, type II | -0.0163731 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0160659 |
| SDC4 | syndecan 4 | -0.0159768 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0155685 |
| TRAM1 | translocation associated membrane protein 1 | -0.0154562 |
| ANXA2 | annexin A2 | -0.015224 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0151377 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0150377 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0150099 |
| APOL1 | apolipoprotein L, 1 | -0.0147658 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0147062 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0146238 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | -0.0145713 |
| KLF6 | Kruppel-like factor 6 | -0.014547 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0144423 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0143783 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0143639 |
| TFRC | transferrin receptor | -0.0143278 |
| CCNL1 | cyclin L1 | -0.0142703 |
| NOP58 | NOP58 ribonucleoprotein | -0.0142393 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0142241 |
| LMNA | lamin A/C | -0.0141322 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0141225 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0141121 |
| DSG2 | desmoglein 2 | -0.0139963 |
| CDA | cytidine deaminase | -0.0138873 |