| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.0530737 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0504674 |
| FN1 | fibronectin 1 | 0.049411 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0488165 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0345574 |
| RACK1 | receptor for activated C kinase 1 | 0.0344145 |
| SMAD3 | SMAD family member 3 | 0.0319281 |
| ARRDC3 | arrestin domain containing 3 | 0.0305019 |
| FLNA | filamin A, alpha | 0.0276527 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0257218 |
| RPL3 | ribosomal protein L3 | 0.025059 |
| YBX1 | Y box binding protein 1 | 0.0244947 |
| ATP13A3 | ATPase type 13A3 | 0.0237276 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0234056 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0224408 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0212331 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0211376 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0203614 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0202322 |
| SPAG9 | sperm associated antigen 9 | 0.0195945 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0195206 |
| TFG | TRK-fused gene | 0.0190179 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0186702 |
| RASA2 | RAS p21 protein activator 2 | 0.0182109 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0180272 |
| NAV2 | neuron navigator 2 | 0.016269 |
| CCNL1 | cyclin L1 | 0.0156475 |
| HYOU1 | hypoxia up-regulated 1 | 0.0156412 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0156171 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0155699 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0154967 |
| MSN | moesin | 0.0148493 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.014634 |
| PGM3 | phosphoglucomutase 3 | 0.0142598 |
| CABIN1 | calcineurin binding protein 1 | 0.0141279 |
| TPM3 | tropomyosin 3 | 0.0139153 |
| NUP58 | nucleoporin 58 | 0.0136998 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0133536 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0129217 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0128487 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0127094 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0126642 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0124319 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0121402 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0120606 |
| FOSL1 | FOS-like antigen 1 | 0.0120391 |
| PCBP2 | poly(rC) binding protein 2 | 0.0119856 |
| ZNF292 | zinc finger protein 292 | 0.0119504 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0119469 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0119341 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0119283 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0119141 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0117742 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0116542 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0115438 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0114744 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0114288 |
| TNS1 | tensin 1 | 0.0113446 |
| ECT2 | epithelial cell transforming 2 | 0.01128 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0112357 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0111771 |
| NCKAP1 | NCK-associated protein 1 | 0.0111508 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0111224 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0110759 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0107863 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0107303 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0107144 |
| FMNL2 | formin-like 2 | 0.0106828 |
| SZRD1 | SUZ RNA binding domain containing 1 | 0.0105965 |
| MRTFA | myocardin related transcription factor A | 0.0105664 |
| AXL | AXL receptor tyrosine kinase | 0.0104397 |
| PLEC | plectin | 0.010307 |
| VMP1 | vacuole membrane protein 1 | 0.010284 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0102577 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0102255 |
| CASC3 | cancer susceptibility candidate 3 | 0.0101667 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.010136 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.0100637 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.00996049 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.00973447 |
| TAPBP | TAP binding protein (tapasin) | 0.00971178 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00970717 |
| RNF145 | ring finger protein 145 | 0.00965108 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.00963888 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.00960991 |
| NFYA | nuclear transcription factor Y, alpha | 0.00954689 |
| NOTCH2 | notch 2 | 0.00951782 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00932579 |
| SMAD5 | SMAD family member 5 | 0.00928444 |
| KIF16B | kinesin family member 16B | 0.009241 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.00917809 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00917567 |
| HELZ | helicase with zinc finger | 0.00916074 |
| USP3 | ubiquitin specific peptidase 3 | 0.00915098 |
| ICAM1 | intercellular adhesion molecule 1 | 0.00909618 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.00891472 |
| FNBP1L | formin binding protein 1-like | 0.00889896 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00886499 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00880731 |
| DCAF13 | DDB1 and CUL4 associated factor 13 | 0.0087844 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.24033 |
| VIM | vimentin | -0.193797 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.181597 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.161573 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.155241 |
| COL1A2 | collagen, type I, alpha 2 | -0.154165 |
| IER3 | immediate early response 3 | -0.114023 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.108977 |
| CDH13 | cadherin 13 | -0.108464 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0870515 |
| TPM4 | tropomyosin 4 | -0.0838 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0824029 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0810768 |
| TMSB10 | thymosin beta 10 | -0.0798169 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0746192 |
| FBN1 | fibrillin 1 | -0.0738408 |
| COL5A1 | collagen, type V, alpha 1 | -0.0698952 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0697454 |
| ASPH | aspartate beta-hydroxylase | -0.065472 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0606383 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0580927 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0573885 |
| LOXL2 | lysyl oxidase-like 2 | -0.0559918 |
| STC1 | stanniocalcin 1 | -0.0550813 |
| HLA-B | major histocompatibility complex, class I, B | -0.054853 |
| AHNAK | AHNAK nucleoprotein | -0.0540681 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0532001 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0524343 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0523149 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0521432 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0511843 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0488804 |
| ENO1 | enolase 1, (alpha) | -0.046896 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0466996 |
| CAVIN1 | caveolae associated protein 1 | -0.0458025 |
| ACTG1 | actin gamma 1 | -0.0443194 |
| RRBP1 | ribosome binding protein 1 | -0.0436254 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.043502 |
| CANX | calnexin | -0.0432527 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0424202 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0417017 |
| LOX | lysyl oxidase | -0.0402136 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0398957 |
| INHBA | inhibin, beta A | -0.039743 |
| CLMP | CXADR-like membrane protein | -0.0396159 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0386626 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0385541 |
| GLIS3 | GLIS family zinc finger 3 | -0.0365155 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0364713 |
| FTL | ferritin, light polypeptide | -0.0363326 |
| VCAN | versican | -0.035739 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0352335 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0348691 |
| RPS8 | ribosomal protein S8 | -0.0346907 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0341525 |
| COL3A1 | collagen, type III, alpha 1 | -0.0341258 |
| PTMA | prothymosin, alpha | -0.0321366 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0319315 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0313323 |
| MTDH | metadherin | -0.0311672 |
| CADM1 | cell adhesion molecule 1 | -0.0311346 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0309112 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0303111 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0302775 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0299702 |
| S100A6 | S100 calcium binding protein A6 | -0.0298187 |
| CALD1 | caldesmon 1 | -0.0291109 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0290713 |
| RPL35A | ribosomal protein L35a | -0.0284203 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0278329 |
| GNAS | GNAS complex locus | -0.0277726 |
| SDC2 | syndecan 2 | -0.0277717 |
| SQSTM1 | sequestosome 1 | -0.0277591 |
| CD44 | CD44 molecule (Indian blood group) | -0.0276568 |
| S100A10 | S100 calcium binding protein A10 | -0.0267268 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0267105 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0266443 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0265601 |
| RPS6 | ribosomal protein S6 | -0.0258053 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0253095 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0253013 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0250578 |
| IL6 | interleukin 6 | -0.025051 |
| MAP4 | microtubule-associated protein 4 | -0.0245725 |
| EGFR | epidermal growth factor receptor | -0.0245636 |
| RUNX1 | runt-related transcription factor 1 | -0.0245035 |
| OSMR | oncostatin M receptor | -0.0243165 |
| PGK1 | phosphoglycerate kinase 1 | -0.0241063 |
| MAP1B | microtubule-associated protein 1B | -0.0240853 |
| GOLGB1 | golgin B1 | -0.0239527 |
| TMSB4X | thymosin beta 4, X-linked | -0.0233487 |
| RPS24 | ribosomal protein S24 | -0.0232004 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0231769 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0227186 |
| CALU | calumenin | -0.022678 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0224299 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0222592 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.022231 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0221948 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0220534 |
