| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.205055 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.100088 |
| EZR | ezrin | 0.091519 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0872325 |
| RACK1 | receptor for activated C kinase 1 | 0.0841083 |
| TXNRD1 | thioredoxin reductase 1 | 0.0797005 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0653081 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0620801 |
| FTL | ferritin, light polypeptide | 0.0595155 |
| B2M | beta-2-microglobulin | 0.0560952 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.054093 |
| DSPP | dentin sialophosphoprotein | 0.0483888 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0474246 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0471352 |
| VEGFA | vascular endothelial growth factor A | 0.0460498 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.045019 |
| LMO7 | LIM domain 7 | 0.0440953 |
| CCNL1 | cyclin L1 | 0.0390488 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0380068 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0371442 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0367641 |
| FNBP4 | formin binding protein 4 | 0.0361897 |
| SERF2 | small EDRK-rich factor 2 | 0.0353857 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0352728 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0337279 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0330049 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0314224 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0310396 |
| KRT18 | keratin 18, type I | 0.0303998 |
| FAM13A | family with sequence similarity 13, member A | 0.0292859 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0279944 |
| MUC13 | mucin 13, cell surface associated | 0.0267349 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0265608 |
| ANXA1 | annexin A1 | 0.0263709 |
| KLF6 | Kruppel-like factor 6 | 0.0260351 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0251911 |
| EREG | epiregulin | 0.0247169 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0244873 |
| RPL35A | ribosomal protein L35a | 0.0244481 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0243617 |
| OPTN | optineurin | 0.0242991 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0242985 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0240797 |
| MACC1 | metastasis associated in colon cancer 1 | 0.024019 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0233225 |
| FOXP1 | forkhead box P1 | 0.0232709 |
| MYADM | myeloid-associated differentiation marker | 0.0230612 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0227859 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0227538 |
| KPNB1 | karyopherin (importin) beta 1 | 0.022629 |
| NFIB | nuclear factor I/B | 0.0222625 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0220923 |
| TPI1 | triosephosphate isomerase 1 | 0.0217864 |
| RND3 | Rho family GTPase 3 | 0.0215649 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0214381 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0214085 |
| MKRN1 | makorin ring finger protein 1 | 0.0211703 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0210427 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.020851 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0203704 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0201384 |
| TMC5 | transmembrane channel-like 5 | 0.0197945 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0197759 |
| FN1 | fibronectin 1 | 0.0195981 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0192679 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0192243 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0190808 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0190464 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.0188566 |
| NUP58 | nucleoporin 58 | 0.0186456 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0184307 |
| STAG2 | stromal antigen 2 | 0.0178366 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0178342 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0177593 |
| RPL3 | ribosomal protein L3 | 0.0175042 |
| DSTN | destrin (actin depolymerizing factor) | 0.0173404 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0169666 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0169495 |
| SLK | STE20-like kinase | 0.0169286 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0168695 |
| JMJD1C | jumonji domain containing 1C | 0.0168265 |
| YBX3 | Y box binding protein 3 | 0.0167767 |
| TMSB4X | thymosin beta 4, X-linked | 0.0167726 |
| ITSN2 | intersectin 2 | 0.0164611 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0164233 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0163721 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0161233 |
| GOLGA2 | golgin A2 | 0.016084 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0160471 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.0160317 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0159986 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0159191 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0158149 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0156459 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0156349 |
| HKDC1 | hexokinase domain containing 1 | 0.0156245 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0154968 |
| NCKAP1 | NCK-associated protein 1 | 0.0153678 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0151958 |
| CGN | cingulin | 0.0151113 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.179742 |
| AHNAK | AHNAK nucleoprotein | -0.147777 |
| UBC | ubiquitin C | -0.13213 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.120151 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.117309 |
| RPS27A | ribosomal protein S27a | -0.108248 |
| SMAD3 | SMAD family member 3 | -0.104384 |
| ACTN4 | actinin, alpha 4 | -0.103054 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.101256 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0958374 |
| PTMA | prothymosin, alpha | -0.0926792 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0894165 |
| KRT8 | keratin 8, type II | -0.088534 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0874224 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0853505 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.079731 |
| INTS6 | integrator complex subunit 6 | -0.0796716 |
| FNDC3B | fibronectin type III domain containing 3B | -0.075372 |
| TMSB10 | thymosin beta 10 | -0.0749792 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0677034 |
| ASPH | aspartate beta-hydroxylase | -0.066819 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0654263 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0599575 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0559675 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0556339 |
| RPS24 | ribosomal protein S24 | -0.0499012 |
| LAMA4 | laminin, alpha 4 | -0.0487629 |
| RPL23 | ribosomal protein L23 | -0.0484114 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0475686 |
| RPL28 | ribosomal protein L28 | -0.0471396 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0458753 |
| VCL | vinculin | -0.0458688 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0455673 |
| RPLP2 | ribosomal protein, large, P2 | -0.0454323 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0453899 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0435999 |
| RPS8 | ribosomal protein S8 | -0.0432635 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0432444 |
| ENO1 | enolase 1, (alpha) | -0.0428344 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0418341 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0408831 |
| RPS5 | ribosomal protein S5 | -0.0403293 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0399491 |
| RPS16 | ribosomal protein S16 | -0.0395297 |
| ANXA2 | annexin A2 | -0.0393815 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0392527 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0385264 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0381746 |
| VMP1 | vacuole membrane protein 1 | -0.0377803 |
| ACTG1 | actin gamma 1 | -0.0376944 |
| TOP1 | topoisomerase (DNA) I | -0.037453 |
| SDCBP | syndecan binding protein (syntenin) | -0.0364645 |
| MYO1E | myosin IE | -0.0361205 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0359603 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0358016 |
| FAT1 | FAT atypical cadherin 1 | -0.0356792 |
| CTBP2 | C-terminal binding protein 2 | -0.0355698 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0355559 |
| RPLP1 | ribosomal protein, large, P1 | -0.035511 |
| WASF2 | WAS protein family, member 2 | -0.0350467 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.03497 |
| RPS11 | ribosomal protein S11 | -0.0349576 |
| MCL1 | myeloid cell leukemia 1 | -0.0349097 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0349007 |
| AGR2 | anterior gradient 2 | -0.0345622 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0341704 |
| CYRIB | CYFIP related Rac1 interactor B | -0.033429 |
| PCBP2 | poly(rC) binding protein 2 | -0.0329032 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0321137 |
| PTK2 | protein tyrosine kinase 2 | -0.0319746 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0317995 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0317028 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0314432 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0313802 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0308756 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0307618 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0306488 |
| OGA | O-GlcNAcase | -0.0305903 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0304328 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0303812 |
| PLK2 | polo-like kinase 2 | -0.0302421 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0298353 |
| ZNF207 | zinc finger protein 207 | -0.0296925 |
| CANX | calnexin | -0.0295485 |
| RTN3 | reticulon 3 | -0.0294813 |
| CAPN8 | calpain 8 | -0.0293546 |
| POF1B | premature ovarian failure, 1B | -0.0293131 |
| PRKCA | protein kinase C, alpha | -0.0292747 |
| NUP98 | nucleoporin 98kDa | -0.0290913 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0289586 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0288293 |
| RPL21 | ribosomal protein L21 | -0.028821 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0288056 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0280091 |
| PRELID2 | PRELI domain containing 2 | -0.0278466 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.027732 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0275348 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.027235 |
| SBF2 | SET binding factor 2 | -0.0272122 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0271589 |
