| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSPP | dentin sialophosphoprotein | 0.134372 |
| TF | transferrin | 0.0848634 |
| FN1 | fibronectin 1 | 0.0841622 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0808886 |
| RACK1 | receptor for activated C kinase 1 | 0.0649918 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.062226 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0542023 |
| VEGFA | vascular endothelial growth factor A | 0.0518276 |
| C3 | complement component 3 | 0.0466802 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0452492 |
| PEG3 | paternally expressed 3 | 0.0435646 |
| IGF2 | insulin-like growth factor 2 | 0.0406326 |
| MATN3 | matrilin 3 | 0.0402083 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0370625 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0339844 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0333856 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0311101 |
| TNS1 | tensin 1 | 0.0309116 |
| A2M | alpha-2-macroglobulin | 0.0303918 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0295188 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0294259 |
| RPL3 | ribosomal protein L3 | 0.0278678 |
| CRY1 | cryptochrome circadian clock 1 | 0.0259808 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0252728 |
| CCNL1 | cyclin L1 | 0.0242503 |
| GPC6 | glypican 6 | 0.0233192 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0226988 |
| FGA | fibrinogen alpha chain | 0.0226962 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.02248 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0220771 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0220659 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.021339 |
| FGG | fibrinogen gamma chain | 0.0209503 |
| PCM1 | pericentriolar material 1 | 0.0193446 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0188343 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.0184293 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.0181583 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0177918 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0164798 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0164688 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.0164112 |
| HGD | homogentisate 1,2-dioxygenase | 0.0163071 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0161327 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0159062 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0158833 |
| AFDN | afadin, adherens junction formation factor | 0.015845 |
| MYO1B | myosin IB | 0.0155345 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0150249 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0149021 |
| SEPTIN9 | septin 9 | 0.0148913 |
| INSIG2 | insulin induced gene 2 | 0.01481 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0145894 |
| CHKA | choline kinase alpha | 0.0143748 |
| TGOLN2 | trans-golgi network protein 2 | 0.0143721 |
| AHSG | alpha-2-HS-glycoprotein | 0.0143484 |
| ORM1 | orosomucoid 1 | 0.014215 |
| FGL1 | fibrinogen-like 1 | 0.0141007 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0140286 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.013951 |
| CENPF | centromere protein F, 350/400kDa | 0.0137588 |
| RPS15A | ribosomal protein S15a | 0.0137094 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0134122 |
| MKI67 | marker of proliferation Ki-67 | 0.0133689 |
| NPTN | neuroplastin | 0.0133564 |
| PLEC | plectin | 0.0133525 |
| WDR43 | WD repeat domain 43 | 0.0133147 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0131957 |
| SERF2 | small EDRK-rich factor 2 | 0.0131321 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.013065 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0129346 |
| SYN3 | synapsin III | 0.0129285 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.0128782 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0125177 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0124975 |
| HPN | hepsin | 0.0124118 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0123325 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.012242 |
| NCKAP1 | NCK-associated protein 1 | 0.012202 |
| KLF10 | Kruppel-like factor 10 | 0.012201 |
| PBX2 | pre-B-cell leukemia homeobox 2 | 0.0121512 |
| SORT1 | sortilin 1 | 0.0121117 |
| STC2 | stanniocalcin 2 | 0.0121047 |
| FKBP5 | FK506 binding protein 5 | 0.0120646 |
| CD109 | CD109 molecule | 0.0120355 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0119727 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0118459 |
| SNX13 | sorting nexin 13 | 0.0117714 |
| CEP250 | centrosomal protein 250kDa | 0.0116914 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0116506 |
| SEC24C | SEC24 family member C | 0.0115843 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0115383 |
| RBM33 | RNA binding motif protein 33 | 0.0115147 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0114559 |
| WWC1 | WW and C2 domain containing 1 | 0.0113901 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0113278 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0113138 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0113033 |
| RSBN1L | round spermatid basic protein 1-like | 0.0112502 |
| FOXN3 | forkhead box N3 | 0.0111919 |
| KIF5B | kinesin family member 5B | 0.0111563 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.190115 |
| ENO1 | enolase 1, (alpha) | -0.189457 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.185839 |
| RPS27A | ribosomal protein S27a | -0.158625 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.13577 |
| UBC | ubiquitin C | -0.128011 |
| GPC3 | glypican 3 | -0.125159 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.116314 |
| ASPH | aspartate beta-hydroxylase | -0.107563 |
| RPS24 | ribosomal protein S24 | -0.102308 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.10222 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0989183 |
| TMSB10 | thymosin beta 10 | -0.0939404 |
| SVIL | supervillin | -0.0882353 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0826596 |
| RPS8 | ribosomal protein S8 | -0.080482 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0784376 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0777741 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0772848 |
| MT2A | metallothionein 2A | -0.0762689 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0748065 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0682719 |
| RPL37A | ribosomal protein L37a | -0.0677946 |
| RPS6 | ribosomal protein S6 | -0.0621836 |
| RPLP1 | ribosomal protein, large, P1 | -0.0610369 |
| RPL23 | ribosomal protein L23 | -0.0599707 |
| SDC4 | syndecan 4 | -0.059339 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0582706 |
| RPS12 | ribosomal protein S12 | -0.0574129 |
| FRMD5 | FERM domain containing 5 | -0.0568622 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0559177 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0557764 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0547996 |
| KRT8 | keratin 8, type II | -0.0540974 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0535296 |
| APOA2 | apolipoprotein A-II | -0.0522148 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0504273 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0503841 |
| RPS21 | ribosomal protein S21 | -0.0499296 |
| RPL34 | ribosomal protein L34 | -0.0494624 |
| RPLP2 | ribosomal protein, large, P2 | -0.049096 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0487853 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0477166 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0475253 |
| RPL9 | ribosomal protein L9 | -0.0466287 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.045654 |
| HMGA1 | high mobility group AT-hook 1 | -0.0452248 |
| PTMA | prothymosin, alpha | -0.0450019 |
| RPS19 | ribosomal protein S19 | -0.0448882 |
| AHNAK | AHNAK nucleoprotein | -0.0446936 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0444105 |
| RPS29 | ribosomal protein S29 | -0.0431238 |
| RPL38 | ribosomal protein L38 | -0.043107 |
| RPS13 | ribosomal protein S13 | -0.0429727 |
| APOB | apolipoprotein B | -0.042214 |
| ATXN1 | ataxin 1 | -0.0421508 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0420567 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0418154 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0410223 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0409644 |
| RPL5 | ribosomal protein L5 | -0.0403869 |
| JUN | jun proto-oncogene | -0.0395897 |
| RPL12 | ribosomal protein L12 | -0.0394719 |
| LDHA | lactate dehydrogenase A | -0.0393713 |
| CANX | calnexin | -0.039189 |
| RPS25 | ribosomal protein S25 | -0.0391036 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.03899 |
| FAM107B | family with sequence similarity 107, member B | -0.0377954 |
| EHBP1 | EH domain binding protein 1 | -0.0369981 |
| APOE | apolipoprotein E | -0.036512 |
| ACTG1 | actin gamma 1 | -0.0363459 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0361681 |
| RPL31 | ribosomal protein L31 | -0.035981 |
| PKM | pyruvate kinase, muscle | -0.0358336 |
| FLNB | filamin B, beta | -0.0355657 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0352054 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0351275 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0346792 |
| RPS23 | ribosomal protein S23 | -0.0345862 |
| MRTFA | myocardin related transcription factor A | -0.0340986 |
| FOXP1 | forkhead box P1 | -0.0339152 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0338489 |
| RPS5 | ribosomal protein S5 | -0.0335154 |
| FTL | ferritin, light polypeptide | -0.0334824 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0331998 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0330608 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0324786 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0324547 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0322751 |
| PGK1 | phosphoglycerate kinase 1 | -0.0320773 |
| RIGI | RNA sensor RIG-I | -0.0318568 |
| ANO6 | anoctamin 6 | -0.0313199 |
| RPLP0 | ribosomal protein, large, P0 | -0.0312573 |
| RPS3 | ribosomal protein S3 | -0.0311649 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0310356 |
| PLIN2 | perilipin 2 | -0.0308508 |
| MAP1B | microtubule-associated protein 1B | -0.0308184 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0307995 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0307786 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0307774 |
