| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Citalopram (hydrobromide)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.146623 |
| ITGA6 | integrin, alpha 6 | 0.117053 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.113532 |
| DSPP | dentin sialophosphoprotein | 0.109812 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.107326 |
| EZR | ezrin | 0.104373 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.084531 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0785536 |
| LMO7 | LIM domain 7 | 0.0622626 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0613822 |
| VEGFA | vascular endothelial growth factor A | 0.0601948 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0567634 |
| RACK1 | receptor for activated C kinase 1 | 0.0524557 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0472232 |
| ANXA1 | annexin A1 | 0.0463683 |
| GPHN | gephyrin | 0.045142 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0427704 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0423468 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0418996 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0412464 |
| RPL3 | ribosomal protein L3 | 0.0398311 |
| FAT1 | FAT atypical cadherin 1 | 0.0391714 |
| PIGR | polymeric immunoglobulin receptor | 0.0388447 |
| AREG | amphiregulin | 0.0372393 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0361342 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0360536 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0349481 |
| USP6NL | USP6 N-terminal like | 0.0346386 |
| EPCAM | epithelial cell adhesion molecule | 0.0339993 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.033958 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0329657 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0327545 |
| TPM3 | tropomyosin 3 | 0.0318524 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0318518 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0317099 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0316545 |
| TXNIP | thioredoxin interacting protein | 0.0315213 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.031385 |
| KIF5B | kinesin family member 5B | 0.0302666 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0300415 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.029847 |
| PCM1 | pericentriolar material 1 | 0.0298301 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0290979 |
| PCBP2 | poly(rC) binding protein 2 | 0.0285262 |
| MLEC | malectin | 0.0282786 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0281314 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0279365 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0276988 |
| YBX1 | Y box binding protein 1 | 0.0275004 |
| RBM39 | RNA binding motif protein 39 | 0.026863 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0267794 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0266413 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0266237 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0265417 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0264439 |
| AFDN | afadin, adherens junction formation factor | 0.0262245 |
| FNBP1L | formin binding protein 1-like | 0.0259975 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.025742 |
| PDZD8 | PDZ domain containing 8 | 0.025483 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0252166 |
| EMP1 | epithelial membrane protein 1 | 0.0245882 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0244963 |
| XPO1 | exportin 1 | 0.0244954 |
| JUN | jun proto-oncogene | 0.0241112 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0240865 |
| VMP1 | vacuole membrane protein 1 | 0.0240208 |
| CCNL1 | cyclin L1 | 0.0239883 |
| TRIM2 | tripartite motif containing 2 | 0.023903 |
| MUC13 | mucin 13, cell surface associated | 0.0237605 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0236453 |
| ANXA11 | annexin A11 | 0.0235785 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0235659 |
| DSCAM | Down syndrome cell adhesion molecule | 0.02321 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0228078 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0227986 |
| MYO5B | myosin VB | 0.0227409 |
| ZNF638 | zinc finger protein 638 | 0.0226457 |
| ENO1 | enolase 1, (alpha) | 0.022617 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0225061 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0220943 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0218371 |
| CADPS | Ca++-dependent secretion activator | 0.0216354 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0216303 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0215456 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0215138 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0214469 |
| ATF4 | activating transcription factor 4 | 0.021384 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0212277 |
| PTEN | phosphatase and tensin homolog | 0.0210885 |
| EREG | epiregulin | 0.0209666 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0208793 |
| CTBP2 | C-terminal binding protein 2 | 0.0207025 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0204876 |
| NCOR1 | nuclear receptor corepressor 1 | 0.020401 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.020286 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0202442 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0201777 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0200426 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0198532 |
| CALR | calreticulin | 0.019697 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.0998973 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.087622 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0692986 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0644144 |
| TMSB10 | thymosin beta 10 | -0.0596616 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0474858 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0469827 |
| PTMA | prothymosin, alpha | -0.0436238 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0381546 |
| PRSS3 | protease, serine, 3 | -0.0350709 |
| ACTG1 | actin gamma 1 | -0.0314486 |
| RPS24 | ribosomal protein S24 | -0.0297138 |
| AGR2 | anterior gradient 2 | -0.0295915 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0250613 |
| RPLP1 | ribosomal protein, large, P1 | -0.0236472 |
| FLNB | filamin B, beta | -0.0219258 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0213523 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0208943 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0207702 |
| FERMT1 | fermitin family member 1 | -0.0200995 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0199788 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0193866 |
| HMGB1 | high mobility group box 1 | -0.0192271 |
| H1-0 | H1.0 linker histone | -0.0188714 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0186662 |
| ITGB4 | integrin, beta 4 | -0.0186012 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0185459 |
| ANXA2 | annexin A2 | -0.018317 |
| IER3 | immediate early response 3 | -0.0182214 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0178552 |
| IGFL2 | IGF-like family member 2 | -0.017436 |
| RPL34 | ribosomal protein L34 | -0.0173815 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0169995 |
| TNS4 | tensin 4 | -0.0162067 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0161987 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0159114 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0157369 |
| RNF217 | ring finger protein 217 | -0.015463 |
| FOXO1 | forkhead box O1 | -0.0151885 |
| MUC17 | mucin 17, cell surface associated | -0.0149188 |
| RPL9 | ribosomal protein L9 | -0.0148133 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0147919 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0147416 |
| PALLD | palladin, cytoskeletal associated protein | -0.014689 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0145013 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0143263 |
| RPS21 | ribosomal protein S21 | -0.0142814 |
| LAMA4 | laminin, alpha 4 | -0.013734 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.013656 |
| RPS6 | ribosomal protein S6 | -0.0136286 |
| TMEM165 | transmembrane protein 165 | -0.0135462 |
| RPLP2 | ribosomal protein, large, P2 | -0.0135143 |
| S100A10 | S100 calcium binding protein A10 | -0.0133596 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0130658 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0128806 |
| RPS20 | ribosomal protein S20 | -0.0127883 |
| MYO1E | myosin IE | -0.0122646 |
| TFF1 | trefoil factor 1 | -0.012217 |
| FRMD5 | FERM domain containing 5 | -0.0122088 |
| RIN2 | Ras and Rab interactor 2 | -0.0121846 |
| S100A6 | S100 calcium binding protein A6 | -0.0120775 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0119226 |
| SEC24D | SEC24 family member D | -0.011727 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0116968 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0116595 |
| RPL26 | ribosomal protein L26 | -0.0116464 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0113351 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0113182 |
| RPL35A | ribosomal protein L35a | -0.0112062 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0111198 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0111104 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0110847 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0109796 |
| RPL35 | ribosomal protein L35 | -0.0105784 |
| RPL38 | ribosomal protein L38 | -0.0105296 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0100697 |
| RPL39 | ribosomal protein L39 | -0.0100098 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00999065 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.00992194 |
| CAB39 | calcium binding protein 39 | -0.0098901 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00982763 |
| ARF1 | ADP-ribosylation factor 1 | -0.00981322 |
| WLS | wntless Wnt ligand secretion mediator | -0.00971836 |
| ICA1 | islet cell autoantigen 1, 69kDa | -0.00969871 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.00969353 |
| HMGA1 | high mobility group AT-hook 1 | -0.00966879 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00957624 |
| RREB1 | ras responsive element binding protein 1 | -0.00952176 |
| WASF2 | WAS protein family, member 2 | -0.00943252 |
| TMEM45B | transmembrane protein 45B | -0.00943058 |
| ZNF33A | zinc finger protein 33A | -0.00939768 |
| KLK10 | kallikrein-related peptidase 10 | -0.00935678 |
| KIAA1217 | KIAA1217 | -0.00921409 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00917023 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.00911189 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.00867831 |
| RPL28 | ribosomal protein L28 | -0.00864933 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.00860154 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.00859735 |
| EGFR | epidermal growth factor receptor | -0.00859505 |
