| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| THSD4 | thrombospondin, type I, domain containing 4 | 0.13523 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.118565 |
| RACK1 | receptor for activated C kinase 1 | 0.0974376 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0529912 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0521032 |
| FLNB | filamin B, beta | 0.0422168 |
| DSPP | dentin sialophosphoprotein | 0.0410016 |
| EZR | ezrin | 0.0408993 |
| MSI2 | musashi RNA-binding protein 2 | 0.0405502 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0362131 |
| FAT1 | FAT atypical cadherin 1 | 0.0309506 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0279609 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0266813 |
| PON2 | paraoxonase 2 | 0.0261228 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0242101 |
| CTBP2 | C-terminal binding protein 2 | 0.0235349 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0232396 |
| RPL3 | ribosomal protein L3 | 0.0224885 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0220981 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0220822 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0217423 |
| JUN | jun proto-oncogene | 0.0216806 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0211835 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0202703 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0198584 |
| HSPA8 | heat shock 70kDa protein 8 | 0.019795 |
| DNM2 | dynamin 2 | 0.0189942 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0187052 |
| HDLBP | high density lipoprotein binding protein | 0.0177931 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0175235 |
| AHNAK | AHNAK nucleoprotein | 0.0174679 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0174549 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0167127 |
| YBX1 | Y box binding protein 1 | 0.0165234 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0160096 |
| KRT18 | keratin 18, type I | 0.0158195 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0155819 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0151556 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0151399 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0150875 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0143275 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0139179 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0138444 |
| FRMD3 | FERM domain containing 3 | 0.0136304 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0133226 |
| FMNL2 | formin-like 2 | 0.0132578 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0130884 |
| EPHA2 | EPH receptor A2 | 0.0128973 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0127966 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0126539 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0126349 |
| EMP1 | epithelial membrane protein 1 | 0.0124123 |
| PLEC | plectin | 0.012306 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0123015 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0121662 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0121598 |
| ITGA6 | integrin, alpha 6 | 0.0121404 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.01178 |
| NPSR1 | neuropeptide S receptor 1 | 0.0117075 |
| PYGB | phosphorylase, glycogen; brain | 0.0115312 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0113477 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0113269 |
| TOP1 | topoisomerase (DNA) I | 0.0113116 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0113062 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0112986 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0112921 |
| PER1 | period circadian clock 1 | 0.0112754 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0108189 |
| ANXA11 | annexin A11 | 0.0106856 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0105792 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0105605 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0105424 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.010495 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.010422 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0103938 |
| TPI1 | triosephosphate isomerase 1 | 0.0103269 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0103182 |
| ENO1 | enolase 1, (alpha) | 0.0101883 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0101805 |
| ABLIM2 | actin binding LIM protein family, member 2 | 0.0101566 |
| FLNA | filamin A, alpha | 0.0100317 |
| RPS4X | ribosomal protein S4, X-linked | 0.00994501 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.00981117 |
| COBL | cordon-bleu WH2 repeat protein | 0.00980538 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.00974874 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | 0.00973145 |
| SPIDR | scaffolding protein involved in DNA repair | 0.00965433 |
| SSBP3 | single stranded DNA binding protein 3 | 0.00962786 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.00952165 |
| DENND1A | DENN/MADD domain containing 1A | 0.00951814 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.00950038 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00938264 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0093821 |
| CUX1 | cut-like homeobox 1 | 0.00925536 |
| TPM3 | tropomyosin 3 | 0.00920417 |
| LIN54 | lin-54 DREAM MuvB core complex component | 0.0091682 |
| DGKH | diacylglycerol kinase, eta | 0.00916759 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0091295 |
| CD9 | CD9 molecule | 0.00910844 |
| SEPTIN9 | septin 9 | 0.00905924 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116952 |
| RPS6 | ribosomal protein S6 | -0.0928648 |
| RPLP1 | ribosomal protein, large, P1 | -0.0729509 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0649164 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0644018 |
| RPS2 | ribosomal protein S2 | -0.0622865 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0542625 |
| RPS23 | ribosomal protein S23 | -0.0516804 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0500788 |
| RPS19 | ribosomal protein S19 | -0.0428658 |
| RPLP2 | ribosomal protein, large, P2 | -0.0424722 |
| GOLGA4 | golgin A4 | -0.0424633 |
| RPS12 | ribosomal protein S12 | -0.0418777 |
| PTMA | prothymosin, alpha | -0.0374643 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.037455 |
| RPS8 | ribosomal protein S8 | -0.0357108 |
| RPS13 | ribosomal protein S13 | -0.0349563 |
| RPLP0 | ribosomal protein, large, P0 | -0.0349325 |
| TXNRD1 | thioredoxin reductase 1 | -0.0345697 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0331651 |
| RPL12 | ribosomal protein L12 | -0.0326897 |
| RPL26 | ribosomal protein L26 | -0.0326403 |
| RPS29 | ribosomal protein S29 | -0.0323374 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0321517 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0320607 |
| RNF145 | ring finger protein 145 | -0.03201 |
| RPS16 | ribosomal protein S16 | -0.0319781 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0319672 |
| RPS25 | ribosomal protein S25 | -0.031841 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0317964 |
| RPS27A | ribosomal protein S27a | -0.030715 |
| MUC13 | mucin 13, cell surface associated | -0.0306715 |
| RPL9 | ribosomal protein L9 | -0.0299358 |
| RPL37A | ribosomal protein L37a | -0.0297583 |
| PRSS3 | protease, serine, 3 | -0.0297559 |
| WWC1 | WW and C2 domain containing 1 | -0.0294588 |
| RPL28 | ribosomal protein L28 | -0.0289836 |
| RPL34 | ribosomal protein L34 | -0.0287916 |
| RPL21 | ribosomal protein L21 | -0.027682 |
| RPS17 | ribosomal protein S17 | -0.0275661 |
| RPS21 | ribosomal protein S21 | -0.0257083 |
| RPS24 | ribosomal protein S24 | -0.0255821 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.0253139 |
| MYO1E | myosin IE | -0.0252628 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0251536 |
| RPL11 | ribosomal protein L11 | -0.0247687 |
| FOXO1 | forkhead box O1 | -0.0243614 |
| VCL | vinculin | -0.0241315 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0234781 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0234589 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0229308 |
| ATXN1 | ataxin 1 | -0.0228282 |
| RPS5 | ribosomal protein S5 | -0.022764 |
| RPL38 | ribosomal protein L38 | -0.0223712 |
| PKP2 | plakophilin 2 | -0.0223323 |
| RPL19 | ribosomal protein L19 | -0.0222144 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0221139 |
| RPL32 | ribosomal protein L32 | -0.0218902 |
| ASPH | aspartate beta-hydroxylase | -0.0217748 |
| JMJD1C | jumonji domain containing 1C | -0.0217675 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0217448 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0216965 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0214357 |
| RPL31 | ribosomal protein L31 | -0.0213766 |
| TMSB10 | thymosin beta 10 | -0.0213221 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0211562 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0210696 |
| TRIM2 | tripartite motif containing 2 | -0.0205222 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0202609 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0200936 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0200917 |
| NKTR | natural killer cell triggering receptor | -0.020058 |
| HLA-B | major histocompatibility complex, class I, B | -0.0200123 |
| RPS15 | ribosomal protein S15 | -0.0199967 |
| RPL37 | ribosomal protein L37 | -0.0197138 |
| TSPAN8 | tetraspanin 8 | -0.0196928 |
| RPS20 | ribosomal protein S20 | -0.0196025 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0195983 |
| RPS27 | ribosomal protein S27 | -0.0195846 |
| RIGI | RNA sensor RIG-I | -0.0195544 |
| SETD5 | SET domain containing 5 | -0.0193374 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0191835 |
| RPS11 | ribosomal protein S11 | -0.0189861 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0189425 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0187963 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0183404 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0182931 |
| COG5 | component of oligomeric golgi complex 5 | -0.0182795 |
| RPS3 | ribosomal protein S3 | -0.0182769 |
| TMEM45B | transmembrane protein 45B | -0.0181577 |
| FRMD5 | FERM domain containing 5 | -0.0179548 |
| TMEM165 | transmembrane protein 165 | -0.0178261 |
| GDF15 | growth differentiation factor 15 | -0.0176539 |
| FHL2 | four and a half LIM domains 2 | -0.0176465 |
| LIMA1 | LIM domain and actin binding 1 | -0.0175625 |
| RPL5 | ribosomal protein L5 | -0.0175149 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0172769 |
| RPS14 | ribosomal protein S14 | -0.0172231 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0171689 |
| EREG | epiregulin | -0.0167694 |