| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Citalopram (hydrobromide)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.101926 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0721978 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0665444 |
| CD44 | CD44 molecule (Indian blood group) | 0.0563987 |
| RACK1 | receptor for activated C kinase 1 | 0.0553684 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0523585 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0479215 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0473778 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0433511 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.038835 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0386861 |
| FMNL2 | formin-like 2 | 0.0383307 |
| CAPRIN2 | caprin family member 2 | 0.0366431 |
| CADM2 | cell adhesion molecule 2 | 0.0359538 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0350336 |
| TNS3 | tensin 3 | 0.0349267 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0347559 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0345771 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0331595 |
| TP63 | tumor protein p63 | 0.0328763 |
| APP | amyloid beta (A4) precursor protein | 0.0326602 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.030492 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0304104 |
| SET | SET nuclear proto-oncogene | 0.0303095 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0289305 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0286643 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.028276 |
| CANX | calnexin | 0.028053 |
| HLA-B | major histocompatibility complex, class I, B | 0.0277048 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0273518 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0270825 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0269227 |
| MYOF | myoferlin | 0.0263882 |
| EFNA5 | ephrin-A5 | 0.0244046 |
| HDAC9 | histone deacetylase 9 | 0.0243824 |
| EHBP1 | EH domain binding protein 1 | 0.0242844 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0241805 |
| PLK2 | polo-like kinase 2 | 0.0240523 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0238997 |
| RNF213 | ring finger protein 213 | 0.0236916 |
| RPL37A | ribosomal protein L37a | 0.0236806 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0236034 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0235622 |
| EPHA4 | EPH receptor A4 | 0.0235537 |
| DNER | delta/notch-like EGF repeat containing | 0.022978 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0226637 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0224552 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0222356 |
| SLK | STE20-like kinase | 0.0220371 |
| TPM3 | tropomyosin 3 | 0.0219851 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0219009 |
| RPL3 | ribosomal protein L3 | 0.0218497 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0218102 |
| SPAG9 | sperm associated antigen 9 | 0.0216663 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0212432 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0211945 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0211364 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0209323 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0209009 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0208724 |
| TOP1 | topoisomerase (DNA) I | 0.0207144 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0203857 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0198419 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0198366 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0197689 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0195759 |
| B2M | beta-2-microglobulin | 0.0194893 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0193524 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0193298 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0192229 |
| RPS12 | ribosomal protein S12 | 0.018944 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0188652 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0188392 |
| ENO1 | enolase 1, (alpha) | 0.0188186 |
| PRELID2 | PRELI domain containing 2 | 0.0184636 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0184335 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0184271 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.018409 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0181741 |
| EGFR | epidermal growth factor receptor | 0.0178511 |
| CALR | calreticulin | 0.0177176 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0175608 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0175075 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0173988 |
| AHNAK | AHNAK nucleoprotein | 0.0173852 |
| PTK2 | protein tyrosine kinase 2 | 0.0172885 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.01726 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0169102 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0168632 |
| EXOC4 | exocyst complex component 4 | 0.016752 |
| RUNX1 | runt-related transcription factor 1 | 0.0167262 |
| XPO1 | exportin 1 | 0.0167238 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0167186 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0165338 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0164525 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0163923 |
| VCL | vinculin | 0.0163756 |
| YEATS2 | YEATS domain containing 2 | 0.0162542 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0160598 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0160029 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.264467 |
| MT2A | metallothionein 2A | -0.156035 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0724629 |
| TMSB10 | thymosin beta 10 | -0.0687393 |
| VIM | vimentin | -0.0606424 |
| MT1X | metallothionein 1X | -0.04556 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0326356 |
| ACTG1 | actin gamma 1 | -0.0317965 |
| TXNRD1 | thioredoxin reductase 1 | -0.0309522 |
| EGR1 | early growth response 1 | -0.0276114 |
| TMEM41B | transmembrane protein 41B | -0.0266564 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0246036 |
| RPLP0 | ribosomal protein, large, P0 | -0.0203582 |
| RTN4 | reticulon 4 | -0.0202701 |
| MT1E | metallothionein 1E | -0.0183909 |
| S100A10 | S100 calcium binding protein A10 | -0.0182879 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0178456 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0172653 |
| PTMA | prothymosin, alpha | -0.0159843 |
| EMP1 | epithelial membrane protein 1 | -0.0158863 |
| PRDX1 | peroxiredoxin 1 | -0.0157036 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0155596 |
| S100A6 | S100 calcium binding protein A6 | -0.0149287 |
| HMGA1 | high mobility group AT-hook 1 | -0.0146551 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0146285 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0143839 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0142548 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0140723 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0139548 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0139304 |
| RPL5 | ribosomal protein L5 | -0.0138747 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0137734 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.013738 |
| CDCP1 | CUB domain containing protein 1 | -0.0130183 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0126378 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0123776 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0122233 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0120561 |
| FOSL1 | FOS-like antigen 1 | -0.0118342 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0114991 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0114926 |
| RRM2 | ribonucleotide reductase M2 | -0.0114574 |
| FERMT1 | fermitin family member 1 | -0.0112051 |
| YBX3 | Y box binding protein 3 | -0.0111632 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.011128 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0110566 |
| RPLP1 | ribosomal protein, large, P1 | -0.010987 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0108891 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.010721 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0106249 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0106045 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0104597 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0103964 |
| SGO2 | shugoshin 2 | -0.0103355 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0103118 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0102218 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0100453 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00995899 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.00986849 |
| BMERB1 | bMERB domain containing 1 | -0.00986079 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.00983453 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.00972722 |
| ANGPTL4 | angiopoietin-like 4 | -0.00941177 |
| KIF18B | kinesin family member 18B | -0.00935677 |
| ZFR | zinc finger RNA binding protein | -0.00932994 |
| RPS16 | ribosomal protein S16 | -0.00924683 |
| CCNI | cyclin I | -0.00918826 |
| S100A11 | S100 calcium binding protein A11 | -0.00903601 |
| RBM25 | RNA binding motif protein 25 | -0.00900186 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.00893981 |
| SEPTIN7 | septin 7 | -0.00892893 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0088351 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00883229 |
| ERCC1 | excision repair cross-complementation group 1 | -0.00866599 |
| H3-3B | H3.3 histone B | -0.00856999 |
| LHX1 | LIM homeobox 1 | -0.00852386 |
| RPL35 | ribosomal protein L35 | -0.00849938 |
| RPS24 | ribosomal protein S24 | -0.00849516 |
| MIS18BP1 | MIS18 binding protein 1 | -0.00839952 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.00832291 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00790376 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.00779618 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.00767743 |
| HMOX1 | heme oxygenase 1 | -0.00763087 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.00738612 |
| RPL18 | ribosomal protein L18 | -0.00738468 |
| USP12 | ubiquitin specific peptidase 12 | -0.00725572 |
| RPS15 | ribosomal protein S15 | -0.00723115 |
| RPL34 | ribosomal protein L34 | -0.00722265 |
| AREG | amphiregulin | -0.00719092 |
| IER3 | immediate early response 3 | -0.00716172 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.00709167 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00698039 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.00690921 |
| SEC61G | Sec61 gamma subunit | -0.00690623 |
| SRGN | serglycin | -0.00687029 |
| RCAN1 | regulator of calcineurin 1 | -0.00686528 |
| RPS21 | ribosomal protein S21 | -0.00683953 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.00682829 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00681723 |
