| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Citalopram (hydrobromide)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP1 | topoisomerase (DNA) I | 0.048518 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0417272 |
| MKI67 | marker of proliferation Ki-67 | 0.0409397 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0384361 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0357436 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0353918 |
| CES1 | carboxylesterase 1 | 0.0351811 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0348197 |
| SPAG9 | sperm associated antigen 9 | 0.0341468 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0338497 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0326207 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0289416 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0288152 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0286219 |
| RUNX1 | runt-related transcription factor 1 | 0.0281142 |
| HELZ | helicase with zinc finger | 0.0280336 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.02776 |
| MCL1 | myeloid cell leukemia 1 | 0.0268133 |
| TES | testin LIM domain protein | 0.0258966 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0257027 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0253297 |
| HYOU1 | hypoxia up-regulated 1 | 0.024286 |
| TMEM165 | transmembrane protein 165 | 0.0241153 |
| GPATCH2L | G patch domain containing 2-like | 0.0237809 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0235292 |
| MT2A | metallothionein 2A | 0.0234266 |
| NPTN | neuroplastin | 0.022792 |
| RNF145 | ring finger protein 145 | 0.0225732 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0222585 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0222285 |
| PCBP2 | poly(rC) binding protein 2 | 0.0220876 |
| SCFD1 | sec1 family domain containing 1 | 0.0218721 |
| UBC | ubiquitin C | 0.0217841 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0215415 |
| NGLY1 | N-glycanase 1 | 0.0213297 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0211114 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0207822 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0205215 |
| ARRDC3 | arrestin domain containing 3 | 0.0204461 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0204133 |
| CCNL1 | cyclin L1 | 0.0201778 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0201402 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0200158 |
| CCNG2 | cyclin G2 | 0.0196778 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0196131 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0195939 |
| DTNA | dystrobrevin, alpha | 0.0192248 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0191449 |
| SON | SON DNA binding protein | 0.0188534 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0186686 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0181679 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0181443 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0181111 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0177176 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0174478 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0173591 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0173291 |
| PAPOLA | poly(A) polymerase alpha | 0.0167641 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0167622 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0167116 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0166892 |
| OGA | O-GlcNAcase | 0.0166745 |
| USP34 | ubiquitin specific peptidase 34 | 0.0163939 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0162698 |
| JMJD1C | jumonji domain containing 1C | 0.0159277 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0157427 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0157018 |
| ATP13A3 | ATPase type 13A3 | 0.0155812 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0155779 |
| SYAP1 | synapse associated protein 1 | 0.0153113 |
| RBM39 | RNA binding motif protein 39 | 0.0152507 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0150227 |
| RACK1 | receptor for activated C kinase 1 | 0.0149472 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0145692 |
| WDR26 | WD repeat domain 26 | 0.0144727 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0143694 |
| ZNF148 | zinc finger protein 148 | 0.0143399 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0143149 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0142365 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0141757 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0141106 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0141002 |
| TBK1 | TANK-binding kinase 1 | 0.0139712 |
| GOLGB1 | golgin B1 | 0.0139165 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0139126 |
| EP300 | E1A binding protein p300 | 0.0138697 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0138481 |
| SUCO | SUN domain containing ossification factor | 0.0138476 |
| FAM13A | family with sequence similarity 13, member A | 0.0137391 |
| YEATS2 | YEATS domain containing 2 | 0.013719 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0133928 |
| MED13 | mediator complex subunit 13 | 0.01339 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0133759 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0132731 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0131985 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0131971 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0130953 |
| FRY | furry homolog (Drosophila) | 0.0130929 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0129249 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0128746 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.13351 |
| ASPH | aspartate beta-hydroxylase | -0.107244 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0826329 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0747859 |
| TMSB10 | thymosin beta 10 | -0.061423 |
| LAMC2 | laminin, gamma 2 | -0.0566955 |
| ACTG1 | actin gamma 1 | -0.0566516 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0539156 |
| EFNA5 | ephrin-A5 | -0.049623 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0494198 |
| LMO7 | LIM domain 7 | -0.0463605 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0457005 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0443234 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0440171 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0431789 |
| GRAMD1B | GRAM domain containing 1B | -0.0429022 |
| RNF213 | ring finger protein 213 | -0.0418491 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0410604 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0395499 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.038547 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0378489 |
| SMAD3 | SMAD family member 3 | -0.0369126 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.034996 |
| STC1 | stanniocalcin 1 | -0.0344241 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0342942 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0342324 |
| AHNAK | AHNAK nucleoprotein | -0.0332098 |
| CCND1 | cyclin D1 | -0.0331702 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0317002 |
| PKM | pyruvate kinase, muscle | -0.0303885 |
| ANXA2 | annexin A2 | -0.0298722 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0284431 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0281871 |
| FOXP1 | forkhead box P1 | -0.0279266 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0275406 |
| HLA-B | major histocompatibility complex, class I, B | -0.027006 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0269081 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0265687 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0265262 |
| TNS3 | tensin 3 | -0.0262774 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0262647 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0255035 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0254995 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0252434 |
| KRT7 | keratin 7, type II | -0.0247503 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0245083 |
| TRIM56 | tripartite motif containing 56 | -0.0243118 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0242301 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0238054 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0233643 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0231955 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0231342 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0227034 |
| KRT18 | keratin 18, type I | -0.0223684 |
| S100A10 | S100 calcium binding protein A10 | -0.0217535 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0215352 |
| PTMA | prothymosin, alpha | -0.0214653 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0213847 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0213643 |
| SCEL | sciellin | -0.0204956 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0204706 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0202552 |
| EGR1 | early growth response 1 | -0.0201685 |
| MX1 | MX dynamin-like GTPase 1 | -0.0201592 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0198523 |
| CUX1 | cut-like homeobox 1 | -0.0196833 |
| TPM4 | tropomyosin 4 | -0.0194317 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0192627 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0188994 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0186835 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0186396 |
| CST3 | cystatin C | -0.0186114 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0185566 |
| GNAS | GNAS complex locus | -0.018364 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0182369 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0182114 |
| FAM107B | family with sequence similarity 107, member B | -0.0182042 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0177699 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0177419 |
| APP | amyloid beta (A4) precursor protein | -0.0176142 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.017607 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0175091 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0173693 |
| FLNB | filamin B, beta | -0.017265 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0171099 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0170567 |
| IFI44L | interferon-induced protein 44-like | -0.0169466 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0168311 |
| RIN2 | Ras and Rab interactor 2 | -0.0166821 |
| SDC4 | syndecan 4 | -0.0166738 |
| GM2A | GM2 ganglioside activator | -0.0164284 |
| DSG2 | desmoglein 2 | -0.0163527 |
| MYOF | myoferlin | -0.016089 |
| RIGI | RNA sensor RIG-I | -0.0160245 |
| ETV6 | ets variant 6 | -0.0160096 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0159844 |
| RAI14 | retinoic acid induced 14 | -0.0158389 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0157708 |
| IER3 | immediate early response 3 | -0.0156703 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0154689 |
