| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Citalopram (hydrobromide)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0749922 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.062346 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0458537 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0419767 |
| CMIP | c-Maf inducing protein | 0.0365365 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0362294 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0356471 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0352164 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0346647 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0335342 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0332757 |
| PTK2 | protein tyrosine kinase 2 | 0.0332452 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0319808 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.031498 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0313131 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0306977 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.030656 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0290702 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0285851 |
| MCL1 | myeloid cell leukemia 1 | 0.0285675 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0284061 |
| TPM3 | tropomyosin 3 | 0.0281458 |
| ERBIN | erbb2 interacting protein | 0.0279107 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0275672 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.027508 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0271565 |
| RACK1 | receptor for activated C kinase 1 | 0.0269531 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0253316 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0250845 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.02499 |
| RPL3 | ribosomal protein L3 | 0.0242993 |
| FLNB | filamin B, beta | 0.0235275 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0230418 |
| FMNL2 | formin-like 2 | 0.0229156 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0224929 |
| TPD52 | tumor protein D52 | 0.0224042 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0223474 |
| FTL | ferritin, light polypeptide | 0.0221881 |
| VMP1 | vacuole membrane protein 1 | 0.0220444 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0216227 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0214822 |
| RPS12 | ribosomal protein S12 | 0.0209387 |
| NUP58 | nucleoporin 58 | 0.0207665 |
| WDR43 | WD repeat domain 43 | 0.020709 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0205141 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0203539 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0202758 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0199348 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0198693 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0195598 |
| RASAL2 | RAS protein activator like 2 | 0.0193707 |
| PFDN2 | prefoldin subunit 2 | 0.0191976 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0191956 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0191087 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.018611 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0185423 |
| COPA | coatomer protein complex, subunit alpha | 0.0184171 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0183162 |
| RBM25 | RNA binding motif protein 25 | 0.0182005 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0177571 |
| TXNRD1 | thioredoxin reductase 1 | 0.017655 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0175027 |
| KYNU | kynureninase | 0.017492 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0174745 |
| INO80 | INO80 complex subunit | 0.0173727 |
| RPL23 | ribosomal protein L23 | 0.017243 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0170149 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0168589 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0167084 |
| RHOA | ras homolog family member A | 0.0166013 |
| SIK3 | SIK family kinase 3 | 0.0165026 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.016442 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0161526 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0159702 |
| SERF2 | small EDRK-rich factor 2 | 0.0159498 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0159061 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0158872 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0158731 |
| CCNL1 | cyclin L1 | 0.0158158 |
| GOLGA4 | golgin A4 | 0.0158097 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0157587 |
| SPAG5 | sperm associated antigen 5 | 0.0157443 |
| FAM107B | family with sequence similarity 107, member B | 0.0154814 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0154809 |
| FLNA | filamin A, alpha | 0.0154146 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0153587 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0150307 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0150016 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0150015 |
| JMJD1C | jumonji domain containing 1C | 0.0149959 |
| KLC1 | kinesin light chain 1 | 0.014932 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0149171 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0148789 |
| BRD2 | bromodomain containing 2 | 0.0146959 |
| HYOU1 | hypoxia up-regulated 1 | 0.0146564 |
| RAB10 | RAB10, member RAS oncogene family | 0.0145839 |
| KIF1B | kinesin family member 1B | 0.0145676 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0144376 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0142617 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0142373 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.0677416 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0523612 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0503017 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0336526 |
| WWOX | WW domain containing oxidoreductase | -0.0246747 |
| NNMT | nicotinamide N-methyltransferase | -0.0245898 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0223711 |
| TMSB10 | thymosin beta 10 | -0.0217883 |
| VIM | vimentin | -0.020689 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0199566 |
| ANXA2 | annexin A2 | -0.0184314 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0172765 |
| IGF2 | insulin-like growth factor 2 | -0.0165893 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0163862 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0158309 |
| RPS24 | ribosomal protein S24 | -0.015015 |
| SRGN | serglycin | -0.0149999 |
| RPS21 | ribosomal protein S21 | -0.0149454 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0148989 |
| ASPH | aspartate beta-hydroxylase | -0.0140064 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0134013 |
| PTMA | prothymosin, alpha | -0.0133109 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0131838 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0128889 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0128629 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0122767 |
| HMGB1 | high mobility group box 1 | -0.0119884 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0119469 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0115917 |
| YBX3 | Y box binding protein 3 | -0.0115886 |
| TUBA1B | tubulin, alpha 1b | -0.0112916 |
| KNL1 | kinetochore scaffold 1 | -0.0107598 |
| RPS5 | ribosomal protein S5 | -0.0105911 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0105373 |
| PKM | pyruvate kinase, muscle | -0.00999934 |
| ZNF292 | zinc finger protein 292 | -0.0098825 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.00976391 |
| IER3 | immediate early response 3 | -0.00974985 |
| GRAMD1B | GRAM domain containing 1B | -0.0096741 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00946788 |
| RPL9 | ribosomal protein L9 | -0.009452 |
| FGA | fibrinogen alpha chain | -0.0094478 |
| MYL12B | myosin, light chain 12B, regulatory | -0.00925358 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.00914225 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.00873924 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00871842 |
| RPS27A | ribosomal protein S27a | -0.00869957 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.00866207 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.00861556 |
| RSPO3 | R-spondin 3 | -0.00825999 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.00825106 |
| PARK7 | parkinson protein 7 | -0.00817644 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00797684 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.00783774 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.00781952 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00776167 |
| NHSL1 | NHS-like 1 | -0.00772354 |
| TMEM123 | transmembrane protein 123 | -0.00753477 |
| RPL28 | ribosomal protein L28 | -0.00736927 |
| HINT1 | histidine triad nucleotide binding protein 1 | -0.00734497 |
| SDC4 | syndecan 4 | -0.007321 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00723217 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.00720113 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.00718742 |
| CHMP1B | charged multivesicular body protein 1B | -0.00717983 |
| MT1X | metallothionein 1X | -0.00716332 |
| RPL23A | ribosomal protein L23a | -0.00715885 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.00714832 |
| LMNA | lamin A/C | -0.00714494 |
| ZNF804A | zinc finger protein 804A | -0.007109 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.00709524 |
| PFKP | phosphofructokinase, platelet | -0.00707857 |
| ETV1 | ets variant 1 | -0.00696448 |
| ARCN1 | archain 1 | -0.00693524 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.00684383 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | -0.00675354 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.00674867 |
| LAMB1 | laminin, beta 1 | -0.00672858 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.00665156 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.00656552 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00653417 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00648182 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.00641085 |
| IGF1R | insulin-like growth factor 1 receptor | -0.00638386 |
| ATF5 | activating transcription factor 5 | -0.00633058 |
| S100A11 | S100 calcium binding protein A11 | -0.00631368 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.00629502 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.0062948 |
| SRSF10 | serine/arginine-rich splicing factor 10 | -0.0062781 |
| FHIT | fragile histidine triad | -0.00625787 |
| CPNE3 | copine III | -0.00614749 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.00613326 |
| NFIA | nuclear factor I/A | -0.00612054 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | -0.00600334 |
| EMP2 | epithelial membrane protein 2 | -0.00598351 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.00595584 |
| KLF6 | Kruppel-like factor 6 | -0.00584856 |
| IL6ST | interleukin 6 signal transducer | -0.00582818 |
| HMGA1 | high mobility group AT-hook 1 | -0.00582658 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00582211 |
