| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Citalopram (hydrobromide)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.120858 |
| PTK2 | protein tyrosine kinase 2 | 0.0700923 |
| FAM13A | family with sequence similarity 13, member A | 0.0650521 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0631145 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0629968 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0592851 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0586614 |
| CDC73 | cell division cycle 73 | 0.0547378 |
| PTMA | prothymosin, alpha | 0.0531638 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0509519 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0507759 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0487643 |
| RBM39 | RNA binding motif protein 39 | 0.0469141 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0466637 |
| HELZ | helicase with zinc finger | 0.0460019 |
| ATP13A3 | ATPase type 13A3 | 0.0451748 |
| RNF145 | ring finger protein 145 | 0.044142 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0435457 |
| CALR | calreticulin | 0.0432064 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0430399 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0424532 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0422764 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0412059 |
| CD109 | CD109 molecule | 0.0406804 |
| RACK1 | receptor for activated C kinase 1 | 0.0405447 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.039574 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0388535 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0386359 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0384793 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0378121 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0375778 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0373153 |
| HMGA2 | high mobility group AT-hook 2 | 0.0372688 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0370776 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0355387 |
| OGA | O-GlcNAcase | 0.0352649 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0350649 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0350178 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0348973 |
| ENO1 | enolase 1, (alpha) | 0.0347632 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0339922 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0337028 |
| ANK2 | ankyrin 2, neuronal | 0.0336642 |
| MATR3 | matrin 3 | 0.0333705 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0333383 |
| LAMB1 | laminin, beta 1 | 0.0332632 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0332543 |
| ARRDC3 | arrestin domain containing 3 | 0.0331281 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0328274 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.03279 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0327218 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0325644 |
| GOLGA4 | golgin A4 | 0.0323804 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.032058 |
| RTN4 | reticulon 4 | 0.031936 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0314211 |
| KYNU | kynureninase | 0.031146 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0309781 |
| YBX1 | Y box binding protein 1 | 0.0305297 |
| CCNL1 | cyclin L1 | 0.0299036 |
| PDE10A | phosphodiesterase 10A | 0.0294919 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0294457 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0293848 |
| RPS17 | ribosomal protein S17 | 0.0293645 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0293276 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0293215 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0293002 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0291801 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0290479 |
| CDC27 | cell division cycle 27 | 0.0288768 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0288416 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0286525 |
| CDK17 | cyclin-dependent kinase 17 | 0.0280323 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0279764 |
| SFTPA2 | surfactant protein A2 | 0.0279429 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0278622 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0277294 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0274427 |
| TMEM87A | transmembrane protein 87A | 0.0273799 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0273775 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0272515 |
| CCDC91 | coiled-coil domain containing 91 | 0.0268911 |
| GPHN | gephyrin | 0.0266319 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0265798 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0264335 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0264318 |
| TPR | translocated promoter region, nuclear basket protein | 0.0263485 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0263386 |
| NAV3 | neuron navigator 3 | 0.026265 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0262002 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0260522 |
| GDNF | glial cell derived neurotrophic factor | 0.0260217 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0259068 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0256998 |
| MED13L | mediator complex subunit 13-like | 0.0256503 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0255091 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.0253089 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0253088 |
| NBAS | neuroblastoma amplified sequence | 0.0253045 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0252975 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.103066 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.102352 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.100866 |
| LMO7 | LIM domain 7 | -0.0980834 |
| MYO1E | myosin IE | -0.089128 |
| SVIL | supervillin | -0.0831975 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0810332 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0774096 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0772217 |
| LAMC2 | laminin, gamma 2 | -0.0766388 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0749926 |
| MUC16 | mucin 16, cell surface associated | -0.0687668 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.066 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0644891 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0601726 |
| ANXA2 | annexin A2 | -0.0599794 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0591485 |
| MCL1 | myeloid cell leukemia 1 | -0.0587816 |
| ATOSA | atos homolog A | -0.0558399 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0497444 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0491521 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0481606 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0477883 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0444697 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0443988 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0443835 |
| LAMB3 | laminin, beta 3 | -0.0442808 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0442072 |
| RBM47 | RNA binding motif protein 47 | -0.0439302 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0437482 |
| EZR | ezrin | -0.0435348 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0422678 |
| KRT17 | keratin 17, type I | -0.0421531 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0417763 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0415561 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.040502 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.040207 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0387555 |
| ITGB4 | integrin, beta 4 | -0.0387446 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.038552 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0384826 |
| RAI14 | retinoic acid induced 14 | -0.038181 |
| MYO5B | myosin VB | -0.0375773 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0370396 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0369832 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0367322 |
| SDC4 | syndecan 4 | -0.0364974 |
| STC1 | stanniocalcin 1 | -0.0363943 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0363103 |
| INTS6 | integrator complex subunit 6 | -0.0359177 |
| MXD1 | MAX dimerization protein 1 | -0.0356867 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0355399 |
| PARD3 | par-3 family cell polarity regulator | -0.035276 |
| FOXP1 | forkhead box P1 | -0.0352293 |
| AK1 | adenylate kinase 1 | -0.0346825 |
| MAP7 | microtubule-associated protein 7 | -0.0346668 |
| PRKCA | protein kinase C, alpha | -0.0345461 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0342029 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.034117 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.033875 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0332625 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0330207 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.03302 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0327097 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0324189 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.032028 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0318547 |
| NHSL1 | NHS-like 1 | -0.0317822 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0317354 |
| ABHD17C | abhydrolase domain containing 17C | -0.0314906 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.0314504 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0313604 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0313147 |
| POTEF | POTE ankyrin domain family, member F | -0.0310661 |
| PTEN | phosphatase and tensin homolog | -0.030922 |
| KLF6 | Kruppel-like factor 6 | -0.0308872 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0303258 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0302465 |
| ACTG1 | actin gamma 1 | -0.0301979 |
| WASF2 | WAS protein family, member 2 | -0.0301023 |
| ERBIN | erbb2 interacting protein | -0.0300831 |
| RREB1 | ras responsive element binding protein 1 | -0.0299279 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0298691 |
| EGR1 | early growth response 1 | -0.0298544 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0297629 |
| LAMA4 | laminin, alpha 4 | -0.0296872 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0294351 |
| FNIP1 | folliculin interacting protein 1 | -0.0294275 |
| RRBP1 | ribosome binding protein 1 | -0.0292432 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0291834 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0291148 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0290114 |
| OSMR | oncostatin M receptor | -0.0287005 |
| CEP350 | centrosomal protein 350kDa | -0.0286439 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0286401 |
| TAOK3 | TAO kinase 3 | -0.0285061 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0283454 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0281718 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0281447 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0281009 |
