| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.162373 |
| FN1 | fibronectin 1 | 0.123432 |
| RACK1 | receptor for activated C kinase 1 | 0.108647 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0997037 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0968605 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0867783 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0844094 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0752023 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0741164 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0732446 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0697839 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0680222 |
| PTK2 | protein tyrosine kinase 2 | 0.0628527 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0619146 |
| TPM3 | tropomyosin 3 | 0.061782 |
| VEGFA | vascular endothelial growth factor A | 0.0605103 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0575375 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0572411 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0567377 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0563695 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0559783 |
| ARRDC3 | arrestin domain containing 3 | 0.0554864 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0527055 |
| TMF1 | TATA element modulatory factor 1 | 0.0495799 |
| PLEC | plectin | 0.0482422 |
| MSN | moesin | 0.0459534 |
| MYO5B | myosin VB | 0.0453595 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0448738 |
| NUP58 | nucleoporin 58 | 0.0447333 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0445972 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0438395 |
| RCOR1 | REST corepressor 1 | 0.0436662 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0435693 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0435517 |
| CCNL1 | cyclin L1 | 0.0434759 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0433531 |
| RPL3 | ribosomal protein L3 | 0.0428761 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0425338 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0425137 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0398257 |
| FLNA | filamin A, alpha | 0.0395683 |
| PCBP2 | poly(rC) binding protein 2 | 0.0394007 |
| FAM3C | family with sequence similarity 3, member C | 0.0391511 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0391379 |
| NAV2 | neuron navigator 2 | 0.039094 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0389442 |
| NPTN | neuroplastin | 0.0387788 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0373829 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0364944 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0363273 |
| LAMB3 | laminin, beta 3 | 0.0359706 |
| DUSP10 | dual specificity phosphatase 10 | 0.0358421 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0354393 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.035252 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0346023 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0342685 |
| RHOA | ras homolog family member A | 0.034204 |
| HDGF | hepatoma-derived growth factor | 0.0337411 |
| CALR | calreticulin | 0.0336358 |
| ZNF148 | zinc finger protein 148 | 0.0330019 |
| MYO6 | myosin VI | 0.0325189 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0325051 |
| CPNE8 | copine VIII | 0.0323811 |
| RPS12 | ribosomal protein S12 | 0.0319242 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0318366 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0310636 |
| SMAD3 | SMAD family member 3 | 0.0309397 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0309085 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0308913 |
| MKRN1 | makorin ring finger protein 1 | 0.0301422 |
| PAPOLA | poly(A) polymerase alpha | 0.0299433 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0293597 |
| YBX1 | Y box binding protein 1 | 0.0293095 |
| TFG | TRK-fused gene | 0.0291534 |
| DTNA | dystrobrevin, alpha | 0.0290998 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0282726 |
| POTEF | POTE ankyrin domain family, member F | 0.0282084 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0280007 |
| RNF145 | ring finger protein 145 | 0.0277915 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.02769 |
| FAM13A | family with sequence similarity 13, member A | 0.0276073 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.027492 |
| PCM1 | pericentriolar material 1 | 0.0273257 |
| SPAG9 | sperm associated antigen 9 | 0.0271672 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0270322 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0268723 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0267485 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0265537 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0264207 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.026384 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0261859 |
| MEF2A | myocyte enhancer factor 2A | 0.0260679 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0260035 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0259444 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.025736 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0250858 |
| CD109 | CD109 molecule | 0.0249764 |
| ERBIN | erbb2 interacting protein | 0.0249545 |
| TXNRD1 | thioredoxin reductase 1 | 0.0248777 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0248222 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.225621 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.225354 |
| ACTG1 | actin gamma 1 | -0.118115 |
| TMSB10 | thymosin beta 10 | -0.0907138 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0877742 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0817867 |
| MT2A | metallothionein 2A | -0.073317 |
| S100A10 | S100 calcium binding protein A10 | -0.0695279 |
| AHNAK | AHNAK nucleoprotein | -0.0615897 |
| ANXA2 | annexin A2 | -0.0579206 |
| CCND1 | cyclin D1 | -0.0567023 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0539533 |
| RPL34 | ribosomal protein L34 | -0.053463 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0531626 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0493376 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0481984 |
| SDC4 | syndecan 4 | -0.0480905 |
| SQSTM1 | sequestosome 1 | -0.0479948 |
| S100A6 | S100 calcium binding protein A6 | -0.0456099 |
| PTMA | prothymosin, alpha | -0.0438299 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0408148 |
| RPS24 | ribosomal protein S24 | -0.0401558 |
| ARF1 | ADP-ribosylation factor 1 | -0.0398388 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.036454 |
| GNAS | GNAS complex locus | -0.0351969 |
| CANX | calnexin | -0.0351707 |
| TMEM263 | transmembrane protein 263 | -0.0347775 |
| RPLP1 | ribosomal protein, large, P1 | -0.034363 |
| RPS23 | ribosomal protein S23 | -0.0342572 |
| RPL35A | ribosomal protein L35a | -0.033089 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0330672 |
| CCNI | cyclin I | -0.0319782 |
| RPS29 | ribosomal protein S29 | -0.0318943 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0318741 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0316251 |
| RPLP0 | ribosomal protein, large, P0 | -0.0316 |
| NPC2 | Niemann-Pick disease, type C2 | -0.031599 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0307719 |
| RPS27A | ribosomal protein S27a | -0.0303766 |
| RPLP2 | ribosomal protein, large, P2 | -0.0298687 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0298579 |
| RPL32 | ribosomal protein L32 | -0.0297553 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0297144 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0295592 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0294756 |
| DSG2 | desmoglein 2 | -0.0293916 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0285774 |
| RPS21 | ribosomal protein S21 | -0.0284189 |
| PLAU | plasminogen activator, urokinase | -0.0270179 |
| KRT7 | keratin 7, type II | -0.026784 |
| KRT8 | keratin 8, type II | -0.0267304 |
| HMGB2 | high mobility group box 2 | -0.0261685 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0258748 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0253891 |
| RPS16 | ribosomal protein S16 | -0.0253631 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0248979 |
| RPS6 | ribosomal protein S6 | -0.0246472 |
| FKBP5 | FK506 binding protein 5 | -0.0243165 |
| RPS8 | ribosomal protein S8 | -0.0240391 |
| RPL6 | ribosomal protein L6 | -0.023897 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0234959 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0233442 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0233082 |
| RPS13 | ribosomal protein S13 | -0.0231569 |
| RPL8 | ribosomal protein L8 | -0.0231513 |
| H1-0 | H1.0 linker histone | -0.0230804 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.022961 |
| RPS14 | ribosomal protein S14 | -0.0228161 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0227425 |
| RPL28 | ribosomal protein L28 | -0.0225701 |
| IER3 | immediate early response 3 | -0.0221451 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0220206 |
| LMO7 | LIM domain 7 | -0.0218823 |
| RPS19 | ribosomal protein S19 | -0.0217918 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0217808 |
| RRBP1 | ribosome binding protein 1 | -0.021674 |
| RPL9 | ribosomal protein L9 | -0.0216075 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.021472 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0214706 |
| TOP1 | topoisomerase (DNA) I | -0.0212036 |
| RPS5 | ribosomal protein S5 | -0.0211409 |
| HMGB1 | high mobility group box 1 | -0.0211408 |
| FCHO2 | FCH domain only 2 | -0.0209215 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0208247 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0207832 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0206889 |
| EGR1 | early growth response 1 | -0.0205952 |
| EREG | epiregulin | -0.0205502 |
| TFRC | transferrin receptor | -0.0205077 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0204705 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.020311 |
| RPL38 | ribosomal protein L38 | -0.0200262 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0200226 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0199151 |
| KLF6 | Kruppel-like factor 6 | -0.0197689 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0196558 |
| MUC20 | mucin 20, cell surface associated | -0.0196493 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0195451 |
| LMNA | lamin A/C | -0.0193584 |
| TMSB4X | thymosin beta 4, X-linked | -0.019166 |
