| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0761399 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0671411 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0431919 |
| DST | dystonin | 0.0376518 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0366933 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0363842 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0352206 |
| TPM3 | tropomyosin 3 | 0.03268 |
| MKI67 | marker of proliferation Ki-67 | 0.0324621 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0307953 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.030431 |
| FOXP2 | forkhead box P2 | 0.0295505 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0292549 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0292487 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0275674 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0273698 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0268293 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0248996 |
| THBS1 | thrombospondin 1 | 0.0245059 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0243293 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0239998 |
| CENPE | centromere protein E, 312kDa | 0.0235113 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0233868 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.023291 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0228788 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0221992 |
| CENPF | centromere protein F, 350/400kDa | 0.0221853 |
| ECT2 | epithelial cell transforming 2 | 0.0220574 |
| SPAG5 | sperm associated antigen 5 | 0.0219067 |
| STK38 | serine/threonine kinase 38 | 0.0215709 |
| HDAC9 | histone deacetylase 9 | 0.021539 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0211175 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0207016 |
| CALCR | calcitonin receptor | 0.0206637 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.020512 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0204369 |
| H1-5 | H1.5 linker histone, cluster member | 0.0200698 |
| GASK1B | golgi associated kinase 1B | 0.019923 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0198486 |
| TP53BP2 | tumor protein p53 binding protein 2 | 0.0196987 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0196798 |
| ANLN | anillin, actin binding protein | 0.0195027 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0194192 |
| FLNA | filamin A, alpha | 0.0193971 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.019325 |
| RPL3 | ribosomal protein L3 | 0.0192005 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0185762 |
| EEIG2 | EEIG family member 2 | 0.0185186 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0185101 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.0184655 |
| NRDC | nardilysin convertase | 0.0184031 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.018394 |
| CEP170 | centrosomal protein 170kDa | 0.0182655 |
| SET | SET nuclear proto-oncogene | 0.0182187 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.0180826 |
| IPO7 | importin 7 | 0.0180085 |
| KIF11 | kinesin family member 11 | 0.0177228 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0176492 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0174505 |
| H1-4 | H1.4 linker histone, cluster member | 0.0174275 |
| SHROOM3 | shroom family member 3 | 0.0174026 |
| RACK1 | receptor for activated C kinase 1 | 0.0173847 |
| FIGN | fidgetin | 0.0171045 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0169555 |
| ZFHX4 | zinc finger homeobox 4 | 0.0167572 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0167072 |
| QKI | QKI, KH domain containing, RNA binding | 0.0165737 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.016476 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0163734 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.0163028 |
| NUP155 | nucleoporin 155kDa | 0.016138 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0160193 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0160135 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0159019 |
| TMF1 | TATA element modulatory factor 1 | 0.015898 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0158757 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0157936 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0157746 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0156831 |
| HBS1L | HBS1-like translational GTPase | 0.0155399 |
| AZIN1 | antizyme inhibitor 1 | 0.0155319 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0153535 |
| CCNA2 | cyclin A2 | 0.0152981 |
| CFL2 | cofilin 2 (muscle) | 0.0151393 |
| MEF2A | myocyte enhancer factor 2A | 0.0148096 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0144916 |
| DIAPH3 | diaphanous-related formin 3 | 0.0144883 |
| RHEB | Ras homolog enriched in brain | 0.0143842 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0143831 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0142296 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0141725 |
| ZNF292 | zinc finger protein 292 | 0.0141647 |
| H2AZ2 | H2A.Z variant histone 2 | 0.0141592 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0139722 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0138961 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.013895 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0138773 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0137965 |
| STIL | SCL/TAL1 interrupting locus | 0.0137529 |
| TRIM37 | tripartite motif containing 37 | 0.0137443 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.18499 |
| TMSB10 | thymosin beta 10 | -0.134218 |
| PTMA | prothymosin, alpha | -0.125002 |
| CADM2 | cell adhesion molecule 2 | -0.11863 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.111908 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.109598 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.104196 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0904906 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0854093 |
| RPS16 | ribosomal protein S16 | -0.083667 |
| COL3A1 | collagen, type III, alpha 1 | -0.0832523 |
| RPS6 | ribosomal protein S6 | -0.0828043 |
| RPS8 | ribosomal protein S8 | -0.0787609 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0737581 |
| RPL35A | ribosomal protein L35a | -0.0734596 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0731881 |
| COL1A2 | collagen, type I, alpha 2 | -0.0730022 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0719784 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.071634 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0695795 |
| PCDH9 | protocadherin 9 | -0.0677306 |
| PHIP | pleckstrin homology domain interacting protein | -0.0654799 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0587248 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0585877 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0585556 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0582985 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0562555 |
| GNAS | GNAS complex locus | -0.0535102 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0524787 |
| ACTG1 | actin gamma 1 | -0.0498576 |
| ENO1 | enolase 1, (alpha) | -0.0496966 |
| PGK1 | phosphoglycerate kinase 1 | -0.0489464 |
| B2M | beta-2-microglobulin | -0.0476267 |
| RPL26 | ribosomal protein L26 | -0.0465849 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0455202 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0453386 |
| RPL37A | ribosomal protein L37a | -0.0444907 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0441909 |
| RPS21 | ribosomal protein S21 | -0.0435746 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0435634 |
| HMCN1 | hemicentin 1 | -0.0435435 |
| RPS19 | ribosomal protein S19 | -0.0430164 |
| ITGAV | integrin, alpha V | -0.0422304 |
| LRRC4C | leucine rich repeat containing 4C | -0.0420775 |
| RPL31 | ribosomal protein L31 | -0.0412658 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0410354 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0404373 |
| RPS13 | ribosomal protein S13 | -0.0403024 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0402018 |
| TENM3 | teneurin transmembrane protein 3 | -0.0392163 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.039019 |
| RPL5 | ribosomal protein L5 | -0.0388407 |
| FTL | ferritin, light polypeptide | -0.038055 |
| NRG1 | neuregulin 1 | -0.0379275 |
| SMYD3 | SET and MYND domain containing 3 | -0.0376221 |
| RPLP0 | ribosomal protein, large, P0 | -0.036965 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.036861 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0365506 |
| RPS12 | ribosomal protein S12 | -0.0364917 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0364769 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0364265 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0361935 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0357596 |
| RPL19 | ribosomal protein L19 | -0.0356995 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0352934 |
| RPLP1 | ribosomal protein, large, P1 | -0.0348991 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0341869 |
| GPC3 | glypican 3 | -0.0333898 |
| RSF1 | remodeling and spacing factor 1 | -0.0333811 |
| RPL12 | ribosomal protein L12 | -0.0326758 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.032637 |
| GSE1 | Gse1 coiled-coil protein | -0.0326334 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0318447 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0317752 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0316204 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0312209 |
| USP34 | ubiquitin specific peptidase 34 | -0.0309226 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0304689 |
| RPL36A | ribosomal protein L36a | -0.0303841 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0301452 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0293434 |
| SQSTM1 | sequestosome 1 | -0.0291225 |
| RPL11 | ribosomal protein L11 | -0.028622 |
| RPL23 | ribosomal protein L23 | -0.0286198 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0283371 |
| RPL30 | ribosomal protein L30 | -0.0278382 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0276814 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0275511 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.027538 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0274898 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0274546 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0273413 |
| RPS24 | ribosomal protein S24 | -0.0273286 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0272943 |
| H1-0 | H1.0 linker histone | -0.0271336 |
| RPS27A | ribosomal protein S27a | -0.0270003 |
| RFPL4B | ret finger protein-like 4B | -0.0268987 |
| RPLP2 | ribosomal protein, large, P2 | -0.0268945 |
| APP | amyloid beta (A4) precursor protein | -0.0268299 |
| S100A9 | S100 calcium binding protein A9 | -0.0267721 |
