| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.101478 |
| VIM | vimentin | 0.0975966 |
| NDRG1 | N-myc downstream regulated 1 | 0.0918829 |
| GOLGA4 | golgin A4 | 0.0777769 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0564625 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0562544 |
| CENPF | centromere protein F, 350/400kDa | 0.0561611 |
| AFAP1 | actin filament associated protein 1 | 0.0516667 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0508896 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0504531 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0498395 |
| ZNF292 | zinc finger protein 292 | 0.0489851 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0467539 |
| PGK1 | phosphoglycerate kinase 1 | 0.0465004 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0462485 |
| MKI67 | marker of proliferation Ki-67 | 0.0450572 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0442585 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0390385 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0389337 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0366773 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.036395 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0362011 |
| CD44 | CD44 molecule (Indian blood group) | 0.0358999 |
| ZNF148 | zinc finger protein 148 | 0.035552 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0347504 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0345062 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0331531 |
| NF1 | neurofibromin 1 | 0.0330958 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0324375 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0321574 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0321271 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0320246 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0318134 |
| RLIM | ring finger protein, LIM domain interacting | 0.0313294 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0307007 |
| ACTN4 | actinin, alpha 4 | 0.0304166 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0300968 |
| DIAPH3 | diaphanous-related formin 3 | 0.0298077 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0293093 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0292615 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0291176 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0290302 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0288085 |
| CENPE | centromere protein E, 312kDa | 0.0285937 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0285678 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0283258 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0282847 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0281982 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0280703 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0278762 |
| NUP58 | nucleoporin 58 | 0.0277544 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0277213 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0273238 |
| CDCP1 | CUB domain containing protein 1 | 0.0272645 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0271944 |
| XPO1 | exportin 1 | 0.0267896 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0264988 |
| FLNB | filamin B, beta | 0.0263313 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0263227 |
| NGLY1 | N-glycanase 1 | 0.0262465 |
| OGA | O-GlcNAcase | 0.0261568 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0261106 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0260633 |
| RNF145 | ring finger protein 145 | 0.0256916 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0256469 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0255744 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0251092 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0248509 |
| TMF1 | TATA element modulatory factor 1 | 0.0247818 |
| COPA | coatomer protein complex, subunit alpha | 0.0246931 |
| COG5 | component of oligomeric golgi complex 5 | 0.0246472 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0244237 |
| HM13 | histocompatibility (minor) 13 | 0.0243723 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0243456 |
| SRP54 | signal recognition particle 54kDa | 0.0242486 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0241835 |
| TPX2 | TPX2, microtubule-associated | 0.0239429 |
| OSMR | oncostatin M receptor | 0.0239269 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0239261 |
| TFG | TRK-fused gene | 0.0238817 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0238435 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0237864 |
| ATP13A3 | ATPase type 13A3 | 0.023692 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0236847 |
| ECT2 | epithelial cell transforming 2 | 0.0236073 |
| GPSM2 | G-protein signaling modulator 2 | 0.0234346 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0234255 |
| KIF4A | kinesin family member 4A | 0.023396 |
| MEF2A | myocyte enhancer factor 2A | 0.0231296 |
| YEATS2 | YEATS domain containing 2 | 0.0230106 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0227822 |
| TPD52 | tumor protein D52 | 0.0226687 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0226673 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0226432 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0226289 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0223932 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0223899 |
| CDK19 | cyclin-dependent kinase 19 | 0.0223649 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0222799 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0222596 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.164175 |
| CDH13 | cadherin 13 | -0.121289 |
| COL1A1 | collagen, type I, alpha 1 | -0.117695 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0877891 |
| HLA-B | major histocompatibility complex, class I, B | -0.0866239 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0859594 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0729277 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0722604 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0717317 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0712334 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.066472 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0648715 |
| SP100 | SP100 nuclear antigen | -0.0644872 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.064099 |
| EGR1 | early growth response 1 | -0.0629696 |
| FHIT | fragile histidine triad | -0.062218 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0610426 |
| COL1A2 | collagen, type I, alpha 2 | -0.0604679 |
| MT2A | metallothionein 2A | -0.0600685 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0562121 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0543381 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0541021 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0537037 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0500362 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0484856 |
| GLIS3 | GLIS family zinc finger 3 | -0.0468411 |
| IER3 | immediate early response 3 | -0.0464021 |
| TMSB10 | thymosin beta 10 | -0.046225 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0448876 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0443306 |
| HDAC9 | histone deacetylase 9 | -0.0425538 |
| FN1 | fibronectin 1 | -0.042118 |
| IL1B | interleukin 1, beta | -0.0419887 |
| TNS3 | tensin 3 | -0.0415888 |
| CADM1 | cell adhesion molecule 1 | -0.0411757 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0408012 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.040194 |
| NAV1 | neuron navigator 1 | -0.0398358 |
| COL5A1 | collagen, type V, alpha 1 | -0.0398145 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0393267 |
| RND3 | Rho family GTPase 3 | -0.0389178 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0388395 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0382951 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0381818 |
| RAI14 | retinoic acid induced 14 | -0.0380063 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0374185 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0368798 |
| AHNAK | AHNAK nucleoprotein | -0.0368454 |
| HLA-A | major histocompatibility complex, class I, A | -0.0362469 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0356565 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0352068 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0344622 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0340257 |
| FRMD4A | FERM domain containing 4A | -0.0340047 |
| EGFR | epidermal growth factor receptor | -0.0337383 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.03342 |
| JUN | jun proto-oncogene | -0.0330881 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0329127 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0324102 |
| ANXA2 | annexin A2 | -0.0316396 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.031615 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0308091 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0304779 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0302975 |
| HMGA2 | high mobility group AT-hook 2 | -0.0299832 |
| INHBA | inhibin, beta A | -0.0299472 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0297988 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0297883 |
| TGFB1 | transforming growth factor, beta 1 | -0.0297263 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0296767 |
| MCL1 | myeloid cell leukemia 1 | -0.0291398 |
| COL4A1 | collagen, type IV, alpha 1 | -0.0287731 |
| MTSS1 | metastasis suppressor 1 | -0.0286894 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0284128 |
| CA12 | carbonic anhydrase XII | -0.0283641 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.028246 |
| SQSTM1 | sequestosome 1 | -0.02823 |
| TMEM178B | transmembrane protein 178B | -0.0282223 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0280843 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0278143 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0278057 |
| LOXL2 | lysyl oxidase-like 2 | -0.0276895 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0275974 |
| INTS6 | integrator complex subunit 6 | -0.0275713 |
| RIGI | RNA sensor RIG-I | -0.0273293 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.027249 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0268156 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0266501 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0265015 |
| TNNC1 | troponin C type 1 (slow) | -0.0264173 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0262735 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0258074 |
| TWIST2 | twist family bHLH transcription factor 2 | -0.0253903 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | -0.0250929 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0249804 |
| ADM | adrenomedullin | -0.0248704 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0246567 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0246355 |
| CUX1 | cut-like homeobox 1 | -0.0246115 |
| FBXO32 | F-box protein 32 | -0.024448 |
