| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Citalopram (hydrobromide)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.25307 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0821139 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.080914 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0792633 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.074204 |
| SMYD3 | SET and MYND domain containing 3 | 0.0587882 |
| FGF14 | fibroblast growth factor 14 | 0.0567638 |
| RIT2 | Ras-like without CAAX 2 | 0.0554802 |
| GPC6 | glypican 6 | 0.0524315 |
| NRG1 | neuregulin 1 | 0.051716 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0477853 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0431546 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0425566 |
| SNTG1 | syntrophin, gamma 1 | 0.0425186 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0407603 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0405593 |
| CPE | carboxypeptidase E | 0.0382649 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0367584 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | 0.0367122 |
| VGF | VGF nerve growth factor inducible | 0.0358076 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.0343556 |
| FNDC3A | fibronectin type III domain containing 3A | 0.033284 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0322924 |
| AOPEP | aminopeptidase O (putative) | 0.0294311 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0294211 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0293685 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0287195 |
| EFNA5 | ephrin-A5 | 0.0281977 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0276011 |
| SIK3 | SIK family kinase 3 | 0.0269401 |
| KLHL29 | kelch-like family member 29 | 0.0265329 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0265095 |
| KCTD8 | potassium channel tetramerization domain containing 8 | 0.0258888 |
| SIK2 | salt-inducible kinase 2 | 0.0256203 |
| NBEA | neurobeachin | 0.0254628 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0250396 |
| ZFHX3 | zinc finger homeobox 3 | 0.0250199 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0247416 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0245587 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | 0.0242981 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0241251 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0238236 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0234348 |
| PRKD1 | protein kinase D1 | 0.0226604 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.0226217 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0224019 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0215915 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0212053 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0208994 |
| MAP7 | microtubule-associated protein 7 | 0.0208461 |
| PCBP3 | poly(rC) binding protein 3 | 0.020718 |
| NAV1 | neuron navigator 1 | 0.0205886 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0204489 |
| CNKSR3 | CNKSR family member 3 | 0.020442 |
| TOX | thymocyte selection-associated high mobility group box | 0.0203888 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0200973 |
| INHBA | inhibin, beta A | 0.0198332 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.0198031 |
| MED13L | mediator complex subunit 13-like | 0.0197062 |
| DOCK5 | dedicator of cytokinesis 5 | 0.019693 |
| RORA | RAR-related orphan receptor A | 0.019647 |
| ESRRG | estrogen-related receptor gamma | 0.0195872 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0195853 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0195695 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.0192665 |
| DTNA | dystrobrevin, alpha | 0.0191398 |
| KIF26B | kinesin family member 26B | 0.0191126 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0190764 |
| FAT1 | FAT atypical cadherin 1 | 0.018876 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0188526 |
| DGKB | diacylglycerol kinase, beta 90kDa | 0.0187436 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0187086 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 0.0185026 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0184758 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0183559 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0182998 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0178844 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0177349 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0177059 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | 0.0176728 |
| AUTS2 | autism susceptibility candidate 2 | 0.0175186 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | 0.0171216 |
| EPHA6 | EPH receptor A6 | 0.016893 |
| LSAMP | limbic system-associated membrane protein | 0.016627 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0166207 |
| CDK13 | cyclin-dependent kinase 13 | 0.0165393 |
| JMJD1C | jumonji domain containing 1C | 0.0162244 |
| PTK2 | protein tyrosine kinase 2 | 0.016214 |
| PTCHD4 | patched domain containing 4 | 0.0160651 |
| TUSC3 | tumor suppressor candidate 3 | 0.0160576 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0159951 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 | 0.0159802 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0159658 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0159559 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0159291 |
| ASPH | aspartate beta-hydroxylase | 0.015878 |
| FNIP1 | folliculin interacting protein 1 | 0.0158172 |
| RALYL | RALY RNA binding protein-like | 0.0157792 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0157785 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0157454 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.147064 |
| PTMA | prothymosin, alpha | -0.124611 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0748069 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0506324 |
| TENM1 | teneurin transmembrane protein 1 | -0.05046 |
| PEG10 | paternally expressed 10 | -0.0489547 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0481364 |
| ENO1 | enolase 1, (alpha) | -0.0480346 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0460093 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.04257 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0425263 |
| FTL | ferritin, light polypeptide | -0.0412077 |
| MT2A | metallothionein 2A | -0.0378417 |
| CENPF | centromere protein F, 350/400kDa | -0.037009 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0337748 |
| FAM162A | family with sequence similarity 162, member A | -0.032034 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0311033 |
| PGK1 | phosphoglycerate kinase 1 | -0.0287276 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0276565 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0268354 |
| PKM | pyruvate kinase, muscle | -0.026373 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0258577 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0255989 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0254988 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0249661 |
| RPS6 | ribosomal protein S6 | -0.0244328 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0240221 |
| RTN4 | reticulon 4 | -0.0239851 |
| CALCA | calcitonin-related polypeptide alpha | -0.0231569 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0229289 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0229245 |
| FAM13A | family with sequence similarity 13, member A | -0.0218839 |
| RPL37A | ribosomal protein L37a | -0.0214233 |
| RPS8 | ribosomal protein S8 | -0.0212698 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0207136 |
| ZNF292 | zinc finger protein 292 | -0.0205946 |
| CA8 | carbonic anhydrase VIII | -0.020563 |
| RPS19 | ribosomal protein S19 | -0.0204318 |
| WDR45B | WD repeat domain 45B | -0.0197417 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.01931 |
| RPS3 | ribosomal protein S3 | -0.0189831 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0189695 |
| ACTG1 | actin gamma 1 | -0.0189072 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0184435 |
| RPL8 | ribosomal protein L8 | -0.0183892 |
| NTS | neurotensin | -0.0182204 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0180316 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0178455 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0177908 |
| TPM4 | tropomyosin 4 | -0.0171729 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0170812 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0170282 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0170043 |
| MT1X | metallothionein 1X | -0.0169679 |
| UBB | ubiquitin B | -0.0168434 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.0161659 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0160543 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0158154 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0154207 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.0151978 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.014914 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0148547 |
| NUF2 | NUF2, NDC80 kinetochore complex component | -0.0146548 |
| JUN | jun proto-oncogene | -0.0145646 |
| SEPTIN7 | septin 7 | -0.0145358 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0144879 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.014244 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0142181 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | -0.0141735 |
| RPL19 | ribosomal protein L19 | -0.0140999 |
| YBX1 | Y box binding protein 1 | -0.0140932 |
| RPLP1 | ribosomal protein, large, P1 | -0.0138902 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0137974 |
| LDHA | lactate dehydrogenase A | -0.013769 |
| SRP72 | signal recognition particle 72kDa | -0.0137671 |
| TUBA1B | tubulin, alpha 1b | -0.0137133 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0134695 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0134304 |
| TPX2 | TPX2, microtubule-associated | -0.0134092 |
| RPS27 | ribosomal protein S27 | -0.0132667 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | -0.0132541 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0130149 |
| RPL7 | ribosomal protein L7 | -0.0129749 |
| STMN1 | stathmin 1 | -0.012824 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.0128219 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0126934 |
| TKT | transketolase | -0.0126541 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0125775 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0124707 |
| TPD52 | tumor protein D52 | -0.0123379 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0122843 |
| HMGB1 | high mobility group box 1 | -0.0122342 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0122195 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.0121414 |
| RPS5 | ribosomal protein S5 | -0.01203 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0118439 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0118213 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 | -0.0116961 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0116133 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0115867 |
