| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.318772 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.12283 |
| LSAMP | limbic system-associated membrane protein | 0.10716 |
| RACK1 | receptor for activated C kinase 1 | 0.0816821 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0808868 |
| NRG3 | neuregulin 3 | 0.0653339 |
| FLNA | filamin A, alpha | 0.0638357 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0616953 |
| NLGN1 | neuroligin 1 | 0.0576372 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0530514 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0445462 |
| RAD51B | RAD51 paralog B | 0.0440037 |
| CADM1 | cell adhesion molecule 1 | 0.0438616 |
| FRMD4A | FERM domain containing 4A | 0.0413756 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0395989 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0387864 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0378621 |
| MSI2 | musashi RNA-binding protein 2 | 0.0370958 |
| DST | dystonin | 0.0363906 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0357813 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0330333 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0310133 |
| CDK6 | cyclin-dependent kinase 6 | 0.0306021 |
| TNNC1 | troponin C type 1 (slow) | 0.0292376 |
| FHIT | fragile histidine triad | 0.0290319 |
| FMN1 | formin 1 | 0.0290156 |
| MELTF | melanotransferrin | 0.0284163 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0279323 |
| PLEC | plectin | 0.0277359 |
| HDAC9 | histone deacetylase 9 | 0.0260963 |
| EHBP1 | EH domain binding protein 1 | 0.0257988 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.02501 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0240587 |
| DENND1A | DENN/MADD domain containing 1A | 0.0235653 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0234867 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0230572 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0228639 |
| HDAC4 | histone deacetylase 4 | 0.0226832 |
| SEPTIN9 | septin 9 | 0.0226613 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0224002 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.022004 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0212878 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0211661 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0205415 |
| RPL3 | ribosomal protein L3 | 0.0202667 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.020149 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0194354 |
| CNKSR3 | CNKSR family member 3 | 0.0192968 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.01907 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0190248 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0189635 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.018473 |
| CD109 | CD109 molecule | 0.0184225 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.0183644 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0182665 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0181396 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0179928 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0179182 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0176969 |
| PHF14 | PHD finger protein 14 | 0.0175408 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0172012 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0169932 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0169412 |
| SMYD3 | SET and MYND domain containing 3 | 0.0169187 |
| RNF213 | ring finger protein 213 | 0.0168415 |
| PRELID2 | PRELI domain containing 2 | 0.0168174 |
| TRIM2 | tripartite motif containing 2 | 0.0166962 |
| TRIM33 | tripartite motif containing 33 | 0.0166597 |
| DPP6 | dipeptidyl-peptidase 6 | 0.016421 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0163145 |
| FMNL2 | formin-like 2 | 0.0162289 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0161302 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0161279 |
| ZC3H7B | zinc finger CCCH-type containing 7B | 0.0160538 |
| LINC02798 | long intergenic non-protein coding RNA 2798 | 0.015994 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0159679 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0158895 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0153638 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | 0.0153257 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0150968 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0149656 |
| CDH13 | cadherin 13 | 0.0148848 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0148386 |
| OPHN1 | oligophrenin 1 | 0.0147682 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0144439 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | 0.0144215 |
| RNF144A | ring finger protein 144A | 0.0142071 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0141757 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0141738 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.014119 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0137755 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0136848 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.0135607 |
| CALD1 | caldesmon 1 | 0.013487 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0134713 |
| WDR27 | WD repeat domain 27 | 0.0134175 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0133691 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0132255 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0130586 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0130257 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.177631 |
| VIM | vimentin | -0.14627 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.103272 |
| SQSTM1 | sequestosome 1 | -0.0965956 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0804518 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0776711 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0693985 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0641327 |
| SPAG9 | sperm associated antigen 9 | -0.0631837 |
| CD44 | CD44 molecule (Indian blood group) | -0.0620675 |
| MT2A | metallothionein 2A | -0.0617025 |
| UBC | ubiquitin C | -0.0580653 |
| PKM | pyruvate kinase, muscle | -0.0576865 |
| TXNRD1 | thioredoxin reductase 1 | -0.057635 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0573456 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0526029 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0517722 |
| RPS6 | ribosomal protein S6 | -0.0496725 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0475213 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0474865 |
| PGK1 | phosphoglycerate kinase 1 | -0.0473283 |
| MSN | moesin | -0.0440778 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0432407 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0422 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.042136 |
| TENM1 | teneurin transmembrane protein 1 | -0.0417701 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0406988 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0402586 |
| ENO1 | enolase 1, (alpha) | -0.0373219 |
| ANXA2 | annexin A2 | -0.0363024 |
| RPS3 | ribosomal protein S3 | -0.0359417 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0354516 |
| RTN4 | reticulon 4 | -0.0352141 |
| GOLGA4 | golgin A4 | -0.0350553 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0344097 |
| OXSR1 | oxidative stress responsive 1 | -0.0341689 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.034056 |
| RPL38 | ribosomal protein L38 | -0.0330906 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0324464 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0323576 |
| MAP4 | microtubule-associated protein 4 | -0.0322093 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0319804 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0317205 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0307485 |
| NAV2 | neuron navigator 2 | -0.0305516 |
| SEPTIN7 | septin 7 | -0.0303003 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0302608 |
| CCND1 | cyclin D1 | -0.0294592 |
| CENPF | centromere protein F, 350/400kDa | -0.0294298 |
| ACTG1 | actin gamma 1 | -0.0292522 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0289536 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0286182 |
| PTMA | prothymosin, alpha | -0.0285915 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.02816 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0280583 |
| SFTPA2 | surfactant protein A2 | -0.0280462 |
| RPS23 | ribosomal protein S23 | -0.0279735 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0278695 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.027847 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0272625 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0269668 |
| CLINT1 | clathrin interactor 1 | -0.0267804 |
| EMP1 | epithelial membrane protein 1 | -0.0267055 |
| RPS27A | ribosomal protein S27a | -0.0266342 |
| NDRG1 | N-myc downstream regulated 1 | -0.0264095 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0263871 |
| RPS13 | ribosomal protein S13 | -0.0263669 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0263538 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0260766 |
| RPL32 | ribosomal protein L32 | -0.0259894 |
| CANX | calnexin | -0.0259135 |
| RPLP1 | ribosomal protein, large, P1 | -0.0258896 |
| ATP13A3 | ATPase type 13A3 | -0.0251458 |
| FTL | ferritin, light polypeptide | -0.0249762 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0249597 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0242312 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | -0.024208 |
| RPS2 | ribosomal protein S2 | -0.024092 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0240538 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0239889 |
| POTEF | POTE ankyrin domain family, member F | -0.0238215 |
| RPS8 | ribosomal protein S8 | -0.0237435 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.02345 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0231674 |
| ASPH | aspartate beta-hydroxylase | -0.0229411 |
| ANLN | anillin, actin binding protein | -0.022913 |
| RPL28 | ribosomal protein L28 | -0.0227502 |
| IPO7 | importin 7 | -0.0225291 |
| SUCO | SUN domain containing ossification factor | -0.0222011 |
| H3-3B | H3.3 histone B | -0.022104 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0220798 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0219307 |
| VMP1 | vacuole membrane protein 1 | -0.0219254 |
| RPLP2 | ribosomal protein, large, P2 | -0.0219128 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0217038 |
| RASAL2 | RAS protein activator like 2 | -0.0215919 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.021262 |
| RPS12 | ribosomal protein S12 | -0.0211289 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.021028 |
| TPX2 | TPX2, microtubule-associated | -0.0209294 |
