Citalopram (hydrobromide)_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Citalopram (hydrobromide) perturbation in SNU-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Citalopram (hydrobromide)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
EEF2 eukaryotic translation elongation factor 2 0.0896925
GOLGA4 golgin A4 0.0716571
RPL3 ribosomal protein L3 0.0614384
RACK1 receptor for activated C kinase 1 0.0608553
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0553866
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0546429
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.054642
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0486365
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0432573
ZNF292 zinc finger protein 292 0.0418206
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0407985
NUP58 nucleoporin 58 0.0407226
HSPA8 heat shock 70kDa protein 8 0.0403046
EVI5 ecotropic viral integration site 5 0.0387566
PDGFC platelet derived growth factor C 0.0387284
KMT2E lysine (K)-specific methyltransferase 2E 0.0381983
HDAC9 histone deacetylase 9 0.0372909
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0368446
TJP1 tight junction protein 1 0.0367089
TTC3 tetratricopeptide repeat domain 3 0.0361793
SRRM2 serine/arginine repetitive matrix 2 0.0350549
COPA coatomer protein complex, subunit alpha 0.0340363
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.0332927
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.032435
UBA6 ubiquitin-like modifier activating enzyme 6 0.0322092
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0320482
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0312893
CCNL1 cyclin L1 0.0307852
NBAS neuroblastoma amplified sequence 0.0306002
TFG TRK-fused gene 0.0304801
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0303449
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0302629
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0299752
AKAP9 A kinase (PRKA) anchor protein 9 0.0298595
EPS8 epidermal growth factor receptor pathway substrate 8 0.0296602
WAC WW domain containing adaptor with coiled-coil 0.0292193
PRRC2C proline-rich coiled-coil 2C 0.0290914
ZFC3H1 zinc finger, C3H1-type containing 0.0288413
ARID1A AT rich interactive domain 1A (SWI-like) 0.028705
COG6 component of oligomeric golgi complex 6 0.027567
QKI QKI, KH domain containing, RNA binding 0.0265835
SAMD4A sterile alpha motif domain containing 4A 0.0262906
ANKRD11 ankyrin repeat domain 11 0.0262257
SLTM SAFB-like, transcription modulator 0.0260202
PMM2 phosphomannomutase 2 0.0258418
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.025836
KTN1 kinectin 1 (kinesin receptor) 0.0257669
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0255132
KDM3A lysine (K)-specific demethylase 3A 0.0252278
ZCCHC7 zinc finger, CCHC domain containing 7 0.0251341
ELOVL5 ELOVL fatty acid elongase 5 0.0250665
SEC24D SEC24 family member D 0.0250277
KDM6A lysine (K)-specific demethylase 6A 0.0249859
JMJD1C jumonji domain containing 1C 0.0249329
ZNF644 zinc finger protein 644 0.024838
NAMPT nicotinamide phosphoribosyltransferase 0.0246801
NCKAP1 NCK-associated protein 1 0.0246599
VMP1 vacuole membrane protein 1 0.0244233
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0243782
CALR calreticulin 0.024112
RAB6A RAB6A, member RAS oncogene family 0.0240524
WDR43 WD repeat domain 43 0.02402
PLXNA1 plexin A1 0.0238877
KMT2C lysine (K)-specific methyltransferase 2C 0.0234357
GLS2 glutaminase 2 (liver, mitochondrial) 0.0232952
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.0231663
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.0226457
CASC3 cancer susceptibility candidate 3 0.0224249
YBX1 Y box binding protein 1 0.0221907
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0221608
TSC22D2 TSC22 domain family, member 2 0.0219568
ECT2 epithelial cell transforming 2 0.0217411
SSBP2 single-stranded DNA binding protein 2 0.0217229
HELZ helicase with zinc finger 0.0216058
MED13L mediator complex subunit 13-like 0.0214867
GARS1 glycyl-tRNA synthetase 1 0.0214129
NCEH1 neutral cholesterol ester hydrolase 1 0.0212717
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0210913
SEC24A SEC24 family member A 0.0208154
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0205726
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0205216
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0204269
SMC3 structural maintenance of chromosomes 3 0.0197567
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0197337
EXT1 exostosin glycosyltransferase 1 0.0196376
RBM33 RNA binding motif protein 33 0.0194972
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0193739
PTBP2 polypyrimidine tract binding protein 2 0.0193221
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.0193192
ADAM10 ADAM metallopeptidase domain 10 0.0192979
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0192853
TMF1 TATA element modulatory factor 1 0.0192702
RSRC2 arginine/serine-rich coiled-coil 2 0.0191949
SEC31A SEC31 homolog A (S. cerevisiae) 0.0191931
RYBP RING1 and YY1 binding protein 0.0191691
AUH AU RNA binding protein/enoyl-CoA hydratase 0.0190363
RBM8A RNA binding motif protein 8A 0.0189094
USP15 ubiquitin specific peptidase 15 0.0188309
KDM4C lysine (K)-specific demethylase 4C 0.0187573
SRP54 signal recognition particle 54kDa 0.0187411

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.42364
PTMA prothymosin, alpha -0.226246
AHNAK AHNAK nucleoprotein -0.156815
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.10594
TPT1 tumor protein, translationally-controlled 1 -0.101707
CCND1 cyclin D1 -0.0988796
BMP10 bone morphogenetic protein 10 -0.0854535
RPS6 ribosomal protein S6 -0.0848148
ACTG1 actin gamma 1 -0.07459
ARL4C ADP-ribosylation factor-like 4C -0.0725736
PDE4D phosphodiesterase 4D, cAMP-specific -0.0720059
RPLP1 ribosomal protein, large, P1 -0.0649084
PKM pyruvate kinase, muscle -0.0641695
MKI67 marker of proliferation Ki-67 -0.0573288
RPL7A ribosomal protein L7a -0.0569372
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0558461
RPS23 ribosomal protein S23 -0.0541276
RPLP2 ribosomal protein, large, P2 -0.0529566
S100A6 S100 calcium binding protein A6 -0.0526851
RPL19 ribosomal protein L19 -0.0505859
TMSB4X thymosin beta 4, X-linked -0.0493413
RPS21 ribosomal protein S21 -0.0480411
RPL35A ribosomal protein L35a -0.0467333
RPL31 ribosomal protein L31 -0.0465055
RPL34 ribosomal protein L34 -0.0464099
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.046266
RPS19 ribosomal protein S19 -0.0419157
TM4SF1 transmembrane 4 L six family member 1 -0.0417374
RPL32 ribosomal protein L32 -0.0412875
RPS24 ribosomal protein S24 -0.0409674
S100A4 S100 calcium binding protein A4 -0.04022
TXNRD1 thioredoxin reductase 1 -0.0394028
EIF1 eukaryotic translation initiation factor 1 -0.0389568
RPS11 ribosomal protein S11 -0.0388933
RPS13 ribosomal protein S13 -0.0371887
GLI3 GLI family zinc finger 3 -0.0361588
RPS8 ribosomal protein S8 -0.0358137
MYL12B myosin, light chain 12B, regulatory -0.035716
RPS27A ribosomal protein S27a -0.0355915
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0345469
RPS16 ribosomal protein S16 -0.0333993
RPL38 ribosomal protein L38 -0.0332458
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.0325376
IFI16 interferon, gamma-inducible protein 16 -0.0325256
ZMYND8 zinc finger, MYND-type containing 8 -0.0322267
ZBTB20 zinc finger and BTB domain containing 20 -0.0321312
RPL26 ribosomal protein L26 -0.0320908
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0318595
CCNI cyclin I -0.0316304
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0315628
RPS29 ribosomal protein S29 -0.0315539
GLI2 GLI family zinc finger 2 -0.0310963
RPL28 ribosomal protein L28 -0.030687
RPLP0 ribosomal protein, large, P0 -0.0305793
S100A10 S100 calcium binding protein A10 -0.0305164
HSPB1 heat shock 27kDa protein 1 -0.0303145
TPM4 tropomyosin 4 -0.0299804
RPL27A ribosomal protein L27a -0.0291859
RPS15 ribosomal protein S15 -0.0291743
S100A9 S100 calcium binding protein A9 -0.0289047
RPL11 ribosomal protein L11 -0.0287093
PFN1 profilin 1 -0.0286706
NBEA neurobeachin -0.0282103
TUBB4B tubulin, beta 4B class IVb -0.0280888
HJURP Holliday junction recognition protein -0.0272514
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0272361
RPL12 ribosomal protein L12 -0.027097
SMNDC1 survival motor neuron domain containing 1 -0.026993
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.0269535
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0268004
RPS25 ribosomal protein S25 -0.0267814
GCLM glutamate-cysteine ligase, modifier subunit -0.0265246
ENO1 enolase 1, (alpha) -0.0263383
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0260478
DIAPH2 diaphanous-related formin 2 -0.025266
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.02502
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.0249189
NAV2 neuron navigator 2 -0.0248156
KPNB1 karyopherin (importin) beta 1 -0.0247892
RPL37A ribosomal protein L37a -0.024633
SMC4 structural maintenance of chromosomes 4 -0.0243
RFC3 replication factor C (activator 1) 3, 38kDa -0.0237062
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.022677
SOX6 SRY (sex determining region Y)-box 6 -0.0224416
TPX2 TPX2, microtubule-associated -0.0223338
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0221265
PRDX2 peroxiredoxin 2 -0.021447
SPRY4 sprouty homolog 4 (Drosophila) -0.0211485
NPAS2 neuronal PAS domain protein 2 -0.0211155
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0208524
TUBA1B tubulin, alpha 1b -0.0206521
MAP4 microtubule-associated protein 4 -0.0204458
RPL10A ribosomal protein L10a -0.0204196
PRELID2 PRELI domain containing 2 -0.0202896
GPATCH8 G patch domain containing 8 -0.0199113
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -0.0196869
RPL36A ribosomal protein L36a -0.0196713
BICD1 bicaudal D homolog 1 (Drosophila) -0.0196192
FER fer (fps/fes related) tyrosine kinase -0.0195203
RPL9 ribosomal protein L9 -0.0194923