Citalopram (hydrobromide)_SNU-423 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Citalopram (hydrobromide) perturbation in SNU-423 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Citalopram (hydrobromide)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FN1 fibronectin 1 0.214467
NAMPT nicotinamide phosphoribosyltransferase 0.126074
SOD2 superoxide dismutase 2, mitochondrial 0.121537
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0859502
BICC1 BicC family RNA binding protein 1 0.0834883
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0706813
EXT1 exostosin glycosyltransferase 1 0.0701922
ELL2 elongation factor, RNA polymerase II, 2 0.0683662
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0660006
VCAN versican 0.0657172
MYH9 myosin, heavy chain 9, non-muscle 0.062297
IGFBP3 insulin-like growth factor binding protein 3 0.0598023
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0536444
FNDC3B fibronectin type III domain containing 3B 0.0517068
DST dystonin 0.0516378
ZMYND8 zinc finger, MYND-type containing 8 0.0473572
MKI67 marker of proliferation Ki-67 0.0462991
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.0458254
AKAP12 A kinase (PRKA) anchor protein 12 0.0442911
ANLN anillin, actin binding protein 0.0441658
GLIS3 GLIS family zinc finger 3 0.0431124
SMAD3 SMAD family member 3 0.0421939
USP9X ubiquitin specific peptidase 9, X-linked 0.0406021
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 0.0394388
EEF2 eukaryotic translation elongation factor 2 0.0393208
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.0388001
THBS1 thrombospondin 1 0.0382583
RAI14 retinoic acid induced 14 0.0374064
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 0.0369477
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0365042
DIAPH3 diaphanous-related formin 3 0.0360454
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0359582
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.0354473
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0351123
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0348863
VCL vinculin 0.0337876
ZBTB38 zinc finger and BTB domain containing 38 0.0336412
KYNU kynureninase 0.0329954
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0327359
OSMR oncostatin M receptor 0.0315666
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0310628
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0300671
TPM4 tropomyosin 4 0.0297313
DENND5A DENN/MADD domain containing 5A 0.0295803
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0288203
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0284893
HLA-E major histocompatibility complex, class I, E 0.0284315
FOXP1 forkhead box P1 0.0280605
DCBLD1 discoidin, CUB and LCCL domain containing 1 0.0275788
TNIP1 TNFAIP3 interacting protein 1 0.0275606
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0273877
CENPF centromere protein F, 350/400kDa 0.0269938
LRRC7 leucine rich repeat containing 7 0.0262717
NRP1 neuropilin 1 0.0260103
AFDN afadin, adherens junction formation factor 0.0257813
UGCG UDP-glucose ceramide glucosyltransferase 0.0256409
CUL4B cullin 4B 0.0256385
EHBP1 EH domain binding protein 1 0.0254161
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0253883
TRIP12 thyroid hormone receptor interactor 12 0.0253399
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.0251159
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0250726
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.024939
SBF2 SET binding factor 2 0.0245665
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0245658
RBM39 RNA binding motif protein 39 0.0244951
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0235512
SERINC1 serine incorporator 1 0.0233975
CDK17 cyclin-dependent kinase 17 0.0229906
ATP13A3 ATPase type 13A3 0.0229357
CSDE1 cold shock domain containing E1, RNA-binding 0.0227472
TXNRD1 thioredoxin reductase 1 0.0224165
BRWD3 bromodomain and WD repeat domain containing 3 0.0223684
LPP LIM domain containing preferred translocation partner in lipoma 0.0220516
ITCH itchy E3 ubiquitin protein ligase 0.0220004
KLF7 Kruppel-like factor 7 (ubiquitous) 0.0218993
BCLAF1 BCL2-associated transcription factor 1 0.0218723
ZFAND3 zinc finger, AN1-type domain 3 0.021789
ANKRD28 ankyrin repeat domain 28 0.0217362
GAS2L3 growth arrest-specific 2 like 3 0.0215496
NUP153 nucleoporin 153kDa 0.0213884
INHBA inhibin, beta A 0.021159
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.0211564
CLIC4 chloride intracellular channel 4 0.0209129
AFF4 AF4/FMR2 family, member 4 0.0208706
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0207871
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0205684
BCAR3 breast cancer anti-estrogen resistance 3 0.0203832
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.0203526
AHNAK AHNAK nucleoprotein 0.0202966
MX1 MX dynamin-like GTPase 1 0.0201966
RUNX2 runt-related transcription factor 2 0.0201677
THOC2 THO complex 2 0.02005
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0197991
TOX2 TOX high mobility group box family member 2 0.0197892
OGA O-GlcNAcase 0.0196934
ACSL4 acyl-CoA synthetase long-chain family member 4 0.0194267
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.0193772
KIF4A kinesin family member 4A 0.0192019
RTN4 reticulon 4 0.0191274

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.291039
FTL ferritin, light polypeptide -0.150323
TMSB10 thymosin beta 10 -0.124753
VIM vimentin -0.120907
HLA-B major histocompatibility complex, class I, B -0.117112
MT2A metallothionein 2A -0.111946
RPS6 ribosomal protein S6 -0.107996
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0937928
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0842958
IER3 immediate early response 3 -0.0839374
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0734696
TRIO trio Rho guanine nucleotide exchange factor -0.0696603
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0666191
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0657986
RAB7A RAB7A, member RAS oncogene family -0.0655614
RPLP2 ribosomal protein, large, P2 -0.0653364
TPT1 tumor protein, translationally-controlled 1 -0.0639777
RPLP1 ribosomal protein, large, P1 -0.0638682
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough -0.0634196
RPS23 ribosomal protein S23 -0.0619621
RPS19 ribosomal protein S19 -0.0601402
NDRG1 N-myc downstream regulated 1 -0.0591546
RPS12 ribosomal protein S12 -0.0557397
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.0551013
SQSTM1 sequestosome 1 -0.0550904
RPL23 ribosomal protein L23 -0.054004
RPL37A ribosomal protein L37a -0.0539511
RPS8 ribosomal protein S8 -0.0527751
RPL35A ribosomal protein L35a -0.0527614
RPL9 ribosomal protein L9 -0.051893
RPS24 ribosomal protein S24 -0.051294
INTS6 integrator complex subunit 6 -0.0507186
RPS21 ribosomal protein S21 -0.0469162
ACTG1 actin gamma 1 -0.0462369
B2M beta-2-microglobulin -0.0442888
RPS3 ribosomal protein S3 -0.0441625
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0438607
RPL11 ribosomal protein L11 -0.0438161
ASPH aspartate beta-hydroxylase -0.0431295
RPL5 ribosomal protein L5 -0.0430209
RPL12 ribosomal protein L12 -0.0422681
RPL28 ribosomal protein L28 -0.0420788
CDH13 cadherin 13 -0.0410867
RPL7A ribosomal protein L7a -0.0409791
HLA-A major histocompatibility complex, class I, A -0.0407749
RPL19 ribosomal protein L19 -0.0406723
PKM pyruvate kinase, muscle -0.0399765
ANXA2 annexin A2 -0.037627
RPS4X ribosomal protein S4, X-linked -0.036842
RPL35 ribosomal protein L35 -0.0365945
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0364794
RPL36 ribosomal protein L36 -0.0360841
RPL26 ribosomal protein L26 -0.035917
HMGA2 high mobility group AT-hook 2 -0.0359022
HMGA1 high mobility group AT-hook 1 -0.0356955
MYOF myoferlin -0.0353852
RPS13 ribosomal protein S13 -0.035112
RPS10 ribosomal protein S10 -0.035024
LOC112694756 uncharaterized LOC112694756 -0.0339451
S100A9 S100 calcium binding protein A9 -0.0338104
NAP1L1 nucleosome assembly protein 1-like 1 -0.033659
RPS29 ribosomal protein S29 -0.0332814
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0329225
RPS14 ribosomal protein S14 -0.0325872
HDAC9 histone deacetylase 9 -0.0322394
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0317663
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0315758
RPL31 ribosomal protein L31 -0.031516
DTNA dystrobrevin, alpha -0.0313839
RPLP0 ribosomal protein, large, P0 -0.0313067
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0310561
ENO1 enolase 1, (alpha) -0.0304344
TMEM132D transmembrane protein 132D -0.0302435
RPS25 ribosomal protein S25 -0.030024
RPL32 ribosomal protein L32 -0.0296393
RND3 Rho family GTPase 3 -0.0294131
SLC35F3 solute carrier family 35, member F3 -0.0292618
CTSD cathepsin D -0.029014
ICAM1 intercellular adhesion molecule 1 -0.0288228
GOLGA4 golgin A4 -0.0287589
RPS27A ribosomal protein S27a -0.0286455
PLIN2 perilipin 2 -0.0284571
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0284153
RPS20 ribosomal protein S20 -0.0283856
SEPTIN9 septin 9 -0.0278475
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0273886
RPL27A ribosomal protein L27a -0.0273704
RPS27 ribosomal protein S27 -0.0269119
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -0.026848
EIF4A1 eukaryotic translation initiation factor 4A1 -0.0262033
RPS17 ribosomal protein S17 -0.0261036
ZMIZ1 zinc finger, MIZ-type containing 1 -0.0260196
ANKRD12 ankyrin repeat domain 12 -0.0260038
LDHA lactate dehydrogenase A -0.0259868
EIF1 eukaryotic translation initiation factor 1 -0.0258193
RPL10A ribosomal protein L10a -0.0255722
IFITM3 interferon induced transmembrane protein 3 -0.0254574
IRS2 insulin receptor substrate 2 -0.0254335
SDK1 sidekick cell adhesion molecule 1 -0.0249916
WWOX WW domain containing oxidoreductase -0.024953