| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Citalopram (hydrobromide)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0706682 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0626766 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0525902 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0525775 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0482714 |
| NCKAP1 | NCK-associated protein 1 | 0.039117 |
| RACK1 | receptor for activated C kinase 1 | 0.0389187 |
| RBM39 | RNA binding motif protein 39 | 0.0377943 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0361412 |
| CCNL1 | cyclin L1 | 0.0359812 |
| RPL3 | ribosomal protein L3 | 0.032671 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0322266 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.031592 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.031587 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0303765 |
| TOP1 | topoisomerase (DNA) I | 0.0302785 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0298303 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0297445 |
| USP3 | ubiquitin specific peptidase 3 | 0.0294467 |
| NPTN | neuroplastin | 0.0275545 |
| DSPP | dentin sialophosphoprotein | 0.0265527 |
| YBX1 | Y box binding protein 1 | 0.0254719 |
| MTMR3 | myotubularin related protein 3 | 0.0252588 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0244474 |
| TFG | TRK-fused gene | 0.0242666 |
| FLNA | filamin A, alpha | 0.0239818 |
| MKRN1 | makorin ring finger protein 1 | 0.0239106 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0239083 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0238476 |
| WDR43 | WD repeat domain 43 | 0.023814 |
| VEGFA | vascular endothelial growth factor A | 0.0232545 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0230477 |
| PCBP2 | poly(rC) binding protein 2 | 0.0225708 |
| NUP58 | nucleoporin 58 | 0.0225032 |
| CTBP2 | C-terminal binding protein 2 | 0.022324 |
| HBP1 | HMG-box transcription factor 1 | 0.0222337 |
| GOLGA4 | golgin A4 | 0.021948 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0218888 |
| ZNF292 | zinc finger protein 292 | 0.0218057 |
| MATR3 | matrin 3 | 0.021618 |
| TMF1 | TATA element modulatory factor 1 | 0.0215702 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0215145 |
| SNX9 | sorting nexin 9 | 0.0213593 |
| AFDN | afadin, adherens junction formation factor | 0.020609 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0205515 |
| TPM3 | tropomyosin 3 | 0.0203715 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0203646 |
| HYOU1 | hypoxia up-regulated 1 | 0.0202842 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0202589 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0201717 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0201679 |
| ZNF148 | zinc finger protein 148 | 0.0201345 |
| TMEM39A | transmembrane protein 39A | 0.02008 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0198617 |
| PLEC | plectin | 0.0196344 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0194134 |
| RIOK3 | RIO kinase 3 | 0.0193714 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0193424 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0191663 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0190625 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0189592 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0189332 |
| MYO10 | myosin X | 0.0185272 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.018085 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0178744 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0177923 |
| VMP1 | vacuole membrane protein 1 | 0.0177853 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0177736 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0177714 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0177684 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0176304 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0176107 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0174195 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0173843 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0173035 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.017263 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0172081 |
| RBM26 | RNA binding motif protein 26 | 0.0170192 |
| NSUN2 | NOP2/Sun RNA methyltransferase family, member 2 | 0.0169754 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0168306 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0166681 |
| LRRC1 | leucine rich repeat containing 1 | 0.0166676 |
| CRY1 | cryptochrome circadian clock 1 | 0.0165009 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0164467 |
| RNF145 | ring finger protein 145 | 0.0163617 |
| ATG3 | autophagy related 3 | 0.0160661 |
| PNN | pinin, desmosome associated protein | 0.016049 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0160167 |
| TUFT1 | tuftelin 1 | 0.0160107 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0159042 |
| USP6NL | USP6 N-terminal like | 0.0155581 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0154781 |
| NBAS | neuroblastoma amplified sequence | 0.0153933 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0153568 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0151789 |
| UBQLN1 | ubiquilin 1 | 0.0150976 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0150479 |
| RYK | receptor-like tyrosine kinase | 0.0148929 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0148804 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0147413 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.207976 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.186804 |
| FTL | ferritin, light polypeptide | -0.174564 |
| TMSB10 | thymosin beta 10 | -0.167744 |
| RPS21 | ribosomal protein S21 | -0.0996625 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0895741 |
| RPL28 | ribosomal protein L28 | -0.0811618 |
| RPLP2 | ribosomal protein, large, P2 | -0.0810929 |
| RPLP1 | ribosomal protein, large, P1 | -0.0791633 |
| RPL35A | ribosomal protein L35a | -0.0781058 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0766089 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0742156 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0666551 |
| RPS19 | ribosomal protein S19 | -0.0664046 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0659792 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0645273 |
| RPS6 | ribosomal protein S6 | -0.0637617 |
| RPS13 | ribosomal protein S13 | -0.0619886 |
| IER3 | immediate early response 3 | -0.0616221 |
| RPS24 | ribosomal protein S24 | -0.0605565 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0578729 |
| KRT8 | keratin 8, type II | -0.057824 |
| RPL32 | ribosomal protein L32 | -0.0572236 |
| RPL12 | ribosomal protein L12 | -0.0571185 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0570829 |
| FRMD5 | FERM domain containing 5 | -0.0569798 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.055261 |
| RPS25 | ribosomal protein S25 | -0.0548435 |
| S100A10 | S100 calcium binding protein A10 | -0.0545562 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0536315 |
| EPCAM | epithelial cell adhesion molecule | -0.0535684 |
| CCND1 | cyclin D1 | -0.0525051 |
| RPL31 | ribosomal protein L31 | -0.0515872 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0510682 |
| CST3 | cystatin C | -0.0505837 |
| RPS11 | ribosomal protein S11 | -0.0500597 |
| EHBP1 | EH domain binding protein 1 | -0.049989 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0495426 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0493952 |
| AHNAK | AHNAK nucleoprotein | -0.0492552 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0490514 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0484125 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0483714 |
| RPL37A | ribosomal protein L37a | -0.047795 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0470868 |
| ANXA2 | annexin A2 | -0.0463776 |
| B2M | beta-2-microglobulin | -0.0454838 |
| ACTG1 | actin gamma 1 | -0.0451113 |
| RPL19 | ribosomal protein L19 | -0.0447981 |
| RPL7A | ribosomal protein L7a | -0.0446534 |
| H1-0 | H1.0 linker histone | -0.0445877 |
| RPL36A | ribosomal protein L36a | -0.0444323 |
| RPS29 | ribosomal protein S29 | -0.0433274 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0432104 |
| RPS27A | ribosomal protein S27a | -0.0425702 |
| RPL8 | ribosomal protein L8 | -0.0406294 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0404639 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0402775 |
| PERP | PERP, TP53 apoptosis effector | -0.0401207 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0395714 |
| RPS5 | ribosomal protein S5 | -0.0394736 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0385309 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0384403 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0375728 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.037483 |
| S100A6 | S100 calcium binding protein A6 | -0.0374452 |
| MKI67 | marker of proliferation Ki-67 | -0.0373373 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0371626 |
| RPS16 | ribosomal protein S16 | -0.0369554 |
| NFIA | nuclear factor I/A | -0.0367031 |
| RPL34 | ribosomal protein L34 | -0.0366278 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.036478 |
| GNAS | GNAS complex locus | -0.0364563 |
| RPS8 | ribosomal protein S8 | -0.0364293 |
| RPS15 | ribosomal protein S15 | -0.036392 |
| ZNRF3 | zinc and ring finger 3 | -0.0361709 |
| RPLP0 | ribosomal protein, large, P0 | -0.0361356 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0360541 |
| LDHA | lactate dehydrogenase A | -0.0359582 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0357968 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0357296 |
| RPL36 | ribosomal protein L36 | -0.0355575 |
| EXOC4 | exocyst complex component 4 | -0.0354813 |
| HLA-B | major histocompatibility complex, class I, B | -0.0351382 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0344619 |
| KRT18 | keratin 18, type I | -0.0342895 |
| RPL37 | ribosomal protein L37 | -0.0342446 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0341605 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0341411 |
| RPL15 | ribosomal protein L15 | -0.033764 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0334396 |
| ACTN4 | actinin, alpha 4 | -0.0331338 |
| CUX1 | cut-like homeobox 1 | -0.0327447 |
| SERINC5 | serine incorporator 5 | -0.0324585 |
| PKM | pyruvate kinase, muscle | -0.0322447 |
| H3-3B | H3.3 histone B | -0.0322193 |
| NF1 | neurofibromin 1 | -0.0319938 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0317343 |
| HLA-A | major histocompatibility complex, class I, A | -0.0314382 |
| RPS23 | ribosomal protein S23 | -0.0312442 |
