| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Citalopram (hydrobromide) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Citalopram (hydrobromide)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0711567 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0700906 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0689224 |
| RACK1 | receptor for activated C kinase 1 | 0.039296 |
| INTS6 | integrator complex subunit 6 | 0.0385122 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0367784 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0361994 |
| GOLGA4 | golgin A4 | 0.0291634 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.028278 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0263439 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0262822 |
| TNS1 | tensin 1 | 0.0260549 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0248418 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0234624 |
| FLNA | filamin A, alpha | 0.0230468 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0230031 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.022011 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0218523 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0216492 |
| NDRG1 | N-myc downstream regulated 1 | 0.020562 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0204105 |
| RPL23 | ribosomal protein L23 | 0.0199058 |
| DST | dystonin | 0.0198448 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0198377 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0197701 |
| FMNL2 | formin-like 2 | 0.0197492 |
| NGLY1 | N-glycanase 1 | 0.0194822 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.019436 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0190839 |
| RPL3 | ribosomal protein L3 | 0.0190055 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0188923 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0188531 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0181814 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0181674 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0180062 |
| NUP58 | nucleoporin 58 | 0.0178729 |
| PGM3 | phosphoglucomutase 3 | 0.0177715 |
| CTBP2 | C-terminal binding protein 2 | 0.0169842 |
| HELZ | helicase with zinc finger | 0.0167774 |
| CRY1 | cryptochrome circadian clock 1 | 0.0166158 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0164826 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0164568 |
| RASA2 | RAS p21 protein activator 2 | 0.0164559 |
| TFG | TRK-fused gene | 0.0163687 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0162711 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0161476 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0160085 |
| FTL | ferritin, light polypeptide | 0.0158242 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0157833 |
| VCL | vinculin | 0.0156395 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0155414 |
| COPA | coatomer protein complex, subunit alpha | 0.015424 |
| OGA | O-GlcNAcase | 0.0154091 |
| USP3 | ubiquitin specific peptidase 3 | 0.0153981 |
| YBX1 | Y box binding protein 1 | 0.015149 |
| PCBP3 | poly(rC) binding protein 3 | 0.0151109 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.015076 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0148225 |
| VEGFA | vascular endothelial growth factor A | 0.0147227 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0145532 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0145442 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0143354 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0142644 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0141875 |
| ZNF638 | zinc finger protein 638 | 0.0141686 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0141066 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.014045 |
| SPAG9 | sperm associated antigen 9 | 0.0140369 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0140297 |
| RPL13A | ribosomal protein L13a | 0.0140097 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0138045 |
| DUSP10 | dual specificity phosphatase 10 | 0.0137258 |
| PMM2 | phosphomannomutase 2 | 0.0136302 |
| NPTN | neuroplastin | 0.0136057 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0136035 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0135012 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0133284 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0133132 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0132613 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0132415 |
| PLEC | plectin | 0.0132167 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0130931 |
| SMAD3 | SMAD family member 3 | 0.0129352 |
| FNIP1 | folliculin interacting protein 1 | 0.0128731 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0128641 |
| CABIN1 | calcineurin binding protein 1 | 0.0127862 |
| HDLBP | high density lipoprotein binding protein | 0.0127117 |
| RCOR1 | REST corepressor 1 | 0.0127091 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0125644 |
| STC2 | stanniocalcin 2 | 0.0124901 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0124782 |
| TLE4 | transducin-like enhancer of split 4 | 0.0123847 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0122853 |
| SNX14 | sorting nexin 14 | 0.0122313 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0120994 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.01208 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0120446 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0118418 |
| FAM219A | family with sequence similarity 219, member A | 0.0118002 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0117386 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.310101 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.308915 |
| FN1 | fibronectin 1 | -0.218872 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.214828 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.158266 |
| INHBA | inhibin, beta A | -0.14716 |
| COL1A1 | collagen, type I, alpha 1 | -0.111955 |
| MMP1 | matrix metallopeptidase 1 | -0.110622 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0783701 |
| COL1A2 | collagen, type I, alpha 2 | -0.0725004 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0672142 |
| HLA-B | major histocompatibility complex, class I, B | -0.0657931 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0630732 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0609123 |
| EMP1 | epithelial membrane protein 1 | -0.0603228 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0569022 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0545069 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0523901 |
| CD44 | CD44 molecule (Indian blood group) | -0.0519315 |
| STC1 | stanniocalcin 1 | -0.0513847 |
| AHNAK | AHNAK nucleoprotein | -0.0488165 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0458317 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0435582 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0427435 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0416143 |
| LDHA | lactate dehydrogenase A | -0.0413095 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0393297 |
| CLMP | CXADR-like membrane protein | -0.0391689 |
| ACTG1 | actin gamma 1 | -0.0389951 |
| MT2A | metallothionein 2A | -0.038067 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0346093 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0338175 |
| TMSB10 | thymosin beta 10 | -0.0336691 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0333855 |
| HMGA2 | high mobility group AT-hook 2 | -0.0328215 |
| TPM4 | tropomyosin 4 | -0.0306119 |
| FRMD4A | FERM domain containing 4A | -0.0305755 |
| RPS6 | ribosomal protein S6 | -0.030306 |
| POTEF | POTE ankyrin domain family, member F | -0.0293376 |
| ANXA2 | annexin A2 | -0.0290294 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0286475 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0285321 |
| PKM | pyruvate kinase, muscle | -0.0284567 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0284289 |
| MYO10 | myosin X | -0.02833 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.028311 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0267352 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0265015 |
| ASPH | aspartate beta-hydroxylase | -0.0264088 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0255648 |
| LOX | lysyl oxidase | -0.0255381 |
| DNER | delta/notch-like EGF repeat containing | -0.025363 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0252806 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0248677 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0245096 |
| CCND1 | cyclin D1 | -0.0242379 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0239986 |
| HLA-A | major histocompatibility complex, class I, A | -0.0236794 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0236201 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0233181 |
| CAVIN1 | caveolae associated protein 1 | -0.0233041 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0232506 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0232243 |
| FOXP1 | forkhead box P1 | -0.0230972 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0227961 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0226839 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0224684 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0222019 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0208121 |
| COL3A1 | collagen, type III, alpha 1 | -0.0202723 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0200801 |
| RPS24 | ribosomal protein S24 | -0.0200356 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0198307 |
| UBC | ubiquitin C | -0.0196302 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.019607 |
| RAI14 | retinoic acid induced 14 | -0.0195914 |
| CTSB | cathepsin B | -0.0193992 |
| SEPTIN11 | septin 11 | -0.0192956 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0190744 |
| IER3 | immediate early response 3 | -0.0190423 |
| COL5A2 | collagen, type V, alpha 2 | -0.0189864 |
| CD59 | CD59 molecule, complement regulatory protein | -0.018956 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0188123 |
| PRRX1 | paired related homeobox 1 | -0.0186979 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0185318 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0183835 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0179926 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0179371 |
| VCAN | versican | -0.0173878 |
| HAS2 | hyaluronan synthase 2 | -0.0172359 |
| CANX | calnexin | -0.0170972 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0169274 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0168935 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0168271 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0167717 |
| FBN1 | fibrillin 1 | -0.0167349 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0165912 |
| RPL34 | ribosomal protein L34 | -0.0165762 |
| S100A6 | S100 calcium binding protein A6 | -0.0164079 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0163454 |
