Clear-Cell Metastatic Renal Cell Carcinoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C2931852
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Genes

224 genes associated with the disease Clear-Cell Metastatic Renal Cell Carcinoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACAT1 acetyl-CoA acetyltransferase 1
ACKR3 atypical chemokine receptor 3
ACLY ATP citrate lyase
ACTN4 actinin, alpha 4
ADIPOQ adiponectin, C1Q and collagen domain containing
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDOA aldolase A, fructose-bisphosphate
ALK anaplastic lymphoma receptor tyrosine kinase
ANGPT2 angiopoietin 2
ANKRD37 ankyrin repeat domain 37
ANPEP alanyl (membrane) aminopeptidase
ANXA2 annexin A2
APLN apelin
APLNR apelin receptor
APLP2 amyloid beta (A4) precursor-like protein 2
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
AR androgen receptor
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
AVP arginine vasopressin
AVPR2 arginine vasopressin receptor 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCCIP BRCA2 and CDKN1A interacting protein
BCL2 B-cell CLL/lymphoma 2
C12ORF49 chromosome 12 open reading frame 49
CA9 carbonic anhydrase IX
CCND1 cyclin D1
CCR6 chemokine (C-C motif) receptor 6
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CD163 CD163 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD44 CD44 molecule (Indian blood group)
CD70 CD70 molecule
CD82 CD82 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CDR2 cerebellar degeneration-related protein 2, 62kDa
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIP2A cellular inhibitor of PP2A
CLDN7 claudin 7
CLIP4 CAP-GLY domain containing linker protein family, member 4
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUBN cubilin (intrinsic factor-cobalamin receptor)
CUL2 cullin 2
CUX1 cut-like homeobox 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCTN6 dynactin 6
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK4 docking protein 4
DPP6 dipeptidyl-peptidase 6
DYSF dysferlin
EHD4 EH-domain containing 4
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELOC elongin C
EPAS1 endothelial PAS domain protein 1
EPCAM epithelial cell adhesion molecule
EPHA2 EPH receptor A2
EPO erythropoietin
EPS8L2 EPS8-like 2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESRRA estrogen-related receptor alpha
ESRRG estrogen-related receptor gamma
F2RL3 coagulation factor II (thrombin) receptor-like 3
FAM155A family with sequence similarity 155, member A
FERMT2 fermitin family member 2
FH fumarate hydratase
FHIT fragile histidine triad
FLCN folliculin
FLOT1 flotillin 1
FLT4 fms-related tyrosine kinase 4
FN1 fibronectin 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXC2 forkhead box C2
FOXP3 forkhead box P3
FSTL1 follistatin-like 1
GATA3 GATA binding protein 3
GATA5 GATA binding protein 5
GGT1 gamma-glutamyltransferase 1
GGTLC3 gamma-glutamyltransferase light chain 3
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTO1 glutathione S-transferase omega 1
GSTO2 glutathione S-transferase omega 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HILPDA hypoxia inducible lipid droplet-associated
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNF1B HNF1 homeobox B
HNF4A hepatocyte nuclear factor 4, alpha
HYAL4 hyaluronoglucosaminidase 4
IARS1 isoleucyl-tRNA synthetase 1
IDO1 indoleamine 2,3-dioxygenase 1
IFI27 interferon, alpha-inducible protein 27
IGFBP3 insulin-like growth factor binding protein 3
IL13RA2 interleukin 13 receptor, alpha 2
IL2 interleukin 2
IL6 interleukin 6
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
INSR insulin receptor
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JADE1 jade family PHD finger 1
KDM6A lysine (K)-specific demethylase 6A
KHK ketohexokinase (fructokinase)
KIF20B kinesin family member 20B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK1 kallikrein 1
KLK6 kallikrein-related peptidase 6
KLK7 kallikrein-related peptidase 7
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LAT linker for activation of T cells
LDLR low density lipoprotein receptor
LOX lysyl oxidase
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK3 mitogen-activated protein kinase 3
MED8 mediator complex subunit 8
MET MET proto-oncogene, receptor tyrosine kinase
MME membrane metallo-endopeptidase
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NDRG2 NDRG family member 2
NNMT nicotinamide N-methyltransferase
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
NOX4 NADPH oxidase 4
NSD2 nuclear receptor binding SET domain protein 2
NT5E 5'-nucleotidase, ecto (CD73)
NUSAP1 nucleolar and spindle associated protein 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX8 paired box 8
PBRM1 polybromo 1
PDCD1 programmed cell death 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDZD2 PDZ domain containing 2
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIWIL1 piwi-like RNA-mediated gene silencing 1
PIWIL4 piwi-like RNA-mediated gene silencing 4
PKM pyruvate kinase, muscle
PLIN2 perilipin 2
PRCC papillary renal cell carcinoma (translocation-associated)
PRKCE protein kinase C, epsilon
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTEN phosphatase and tensin homolog
PTHLH parathyroid hormone-like hormone
PTPRU protein tyrosine phosphatase, receptor type, U
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCC2 regulator of chromosome condensation 2
REG1A regenerating islet-derived 1 alpha
RETN resistin
RGN regucalcin
RNF139 ring finger protein 139
S100A1 S100 calcium binding protein A1
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETD2 SET domain containing 2
SFRP1 secreted frizzled-related protein 1
SIRT3 sirtuin 3
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC39A10 solute carrier family 39 (zinc transporter), member 10
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SND1 staphylococcal nuclease and tudor domain containing 1
SOD2 superoxide dismutase 2, mitochondrial
SOX12 SRY (sex determining region Y)-box 12
SOX2 SRY (sex determining region Y)-box 2
SOX30 SRY (sex determining region Y)-box 30
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPOP speckle-type POZ protein
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK11 serine/threonine kinase 11
TCEA1 transcription elongation factor A (SII), 1
TEK TEK tyrosine kinase, endothelial
TERT telomerase reverse transcriptase
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFE3 transcription factor binding to IGHM enhancer 3
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TICAM2 toll-like receptor adaptor molecule 2
TIMP1 TIMP metallopeptidase inhibitor 1
TMED6 transmembrane emp24 protein transport domain containing 6
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TRIM33 tripartite motif containing 33
TWIST1 twist family bHLH transcription factor 1
UNC5C unc-5 homolog C (C. elegans)
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
WNT7A wingless-type MMTV integration site family, member 7A
WWOX WW domain containing oxidoreductase
ZEB1 zinc finger E-box binding homeobox 1
ZHX1 zinc fingers and homeoboxes 1
ZHX2 zinc fingers and homeoboxes 2
ZHX3 zinc fingers and homeoboxes 3
ZNF645 zinc finger protein 645