Cleft Lip With Or Without Cleft Palate Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group developmental (Genetic Association Database)
External Link https://www.disgenet.org/browser/0/1/0/C0810364
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Genes

97 genes associated with the disease Cleft Lip With Or Without Cleft Palate in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
ARHGAP29 Rho GTPase activating protein 29
ASL argininosuccinate lyase
AXIN2 axin 2
BCL3 B-cell CLL/lymphoma 3
BHMT betaine--homocysteine S-methyltransferase
BHMT2 betaine--homocysteine S-methyltransferase 2
BMP4 bone morphogenetic protein 4
BRIP1 BRCA1 interacting protein C-terminal helicase 1
CBS cystathionine-beta-synthase
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CLPTM1 cleft lip and palate associated transmembrane protein 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTNND1 catenin (cadherin-associated protein), delta 1
CUBN cubilin (intrinsic factor-cobalamin receptor)
DHFR dihydrofolate reductase
DLG1 discs, large homolog 1 (Drosophila)
DLX4 distal-less homeobox 4
DNTT DNA nucleotidylexotransferase
DVL2 dishevelled segment polarity protein 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EPHA3 EPH receptor A3
EVC Ellis van Creveld protein
FGF1 fibroblast growth factor 1 (acidic)
FGF9 fibroblast growth factor 9
FOXE1 forkhead box E1
FOXF2 forkhead box F2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GLI2 GLI family zinc finger 2
GLRB glycine receptor, beta
GNMT glycine N-methyltransferase
GREM1 gremlin 1, DAN family BMP antagonist
GRHL3 grainyhead-like 3 (Drosophila)
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HAND2 heart and neural crest derivatives expressed 2
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFT88 intraflagellar transport 88
IRF6 interferon regulatory factor 6
JAG2 jagged 2
JARID2 jumonji, AT rich interactive domain 2
LEF1 lymphoid enhancer-binding factor 1
LOC102724560 cystathionine beta-synthase
MICA MHC class I polypeptide-related sequence A
MSX1 msh homeobox 1
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYH14 myosin, heavy chain 14, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NECTIN1 nectin cell adhesion molecule 1
NECTIN2 nectin cell adhesion molecule 2
NHLH1 nescient helix loop helix 1
NTN1 netrin 1
NUCLEOLIN nucleolin multifunctional protein
PAX7 paired box 7
PAX9 paired box 9
PDGFC platelet derived growth factor C
PTCH1 patched 1
PVR poliovirus receptor
RARA retinoic acid receptor, alpha
RFC1 replication factor C (activator 1) 1, 145kDa
ROR2 receptor tyrosine kinase-like orphan receptor 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC39A3 solute carrier family 39 (zinc transporter), member 3
SNAI1 snail family zinc finger 1
SPRY2 sprouty homolog 2 (Drosophila)
STK32B serine/threonine kinase 32B
SUMO1 small ubiquitin-like modifier 1
TCN2 transcobalamin II
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TP63 tumor protein p63
TPM1 tropomyosin 1 (alpha)
VAX1 ventral anterior homeobox 1
WNT10A wingless-type MMTV integration site family, member 10A
WNT3 wingless-type MMTV integration site family, member 3
WNT3A wingless-type MMTV integration site family, member 3A
WNT9B wingless-type MMTV integration site family, member 9B