Clemastine Gene Set

Dataset DrugBank Drug Targets
Category physical interactions
Type drug
Description 2-[(2R)-1-Methylpyrrolidin-2-yl]ethanol in which the hydrogen of the hydroxy group is substituted by a 1-(4-chlorophenyl)-1-phenylethyl group (R configuration). An antihistamine with antimuscarinic and moderate sedative properties, it is used as its fumarate salt for the symptomatic relief of allergic conditions such as rhinitis, urticaria, conjunctivitis and in pruritic (severe itching) skin conditions. (Chemical Entities of Biological Interest Ontology, CHEBI_3738)
External Link http://www.drugbank.ca/drugs/DB00283
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Genes

3 interacting proteins for the Clemastine drug from the curated DrugBank Drug Targets dataset.

Symbol Name
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
HRH1 histamine receptor H1