| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clobetasol propionate_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.156607 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.106399 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.101327 |
| AHNAK | AHNAK nucleoprotein | 0.0930416 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0926612 |
| NAV2 | neuron navigator 2 | 0.0894188 |
| LDHA | lactate dehydrogenase A | 0.0783378 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0732416 |
| FKBP5 | FK506 binding protein 5 | 0.0728833 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0669484 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0638111 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0625915 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0578384 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0560476 |
| PRELID2 | PRELI domain containing 2 | 0.0515241 |
| UBC | ubiquitin C | 0.0494012 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0468063 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0464717 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0448291 |
| NEBL | nebulette | 0.0445649 |
| CALR | calreticulin | 0.0442996 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0425431 |
| HIP1 | huntingtin interacting protein 1 | 0.0420812 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0415955 |
| ANXA2 | annexin A2 | 0.0395604 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0388738 |
| ADM | adrenomedullin | 0.0375315 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0366468 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0365206 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.036349 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0345624 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0329925 |
| FAM13A | family with sequence similarity 13, member A | 0.032592 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0324822 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.031603 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0315551 |
| DNER | delta/notch-like EGF repeat containing | 0.030991 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0308797 |
| IL6ST | interleukin 6 signal transducer | 0.0298242 |
| PTX3 | pentraxin 3, long | 0.0297503 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0296831 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0294181 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0289726 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0278541 |
| JCAD | junctional cadherin 5 associated | 0.0276508 |
| GPC6 | glypican 6 | 0.0273723 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0266133 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.0261402 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0261301 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0257294 |
| SQSTM1 | sequestosome 1 | 0.025425 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0248056 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0246074 |
| OGA | O-GlcNAcase | 0.024571 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0245266 |
| PCGF5 | polycomb group ring finger 5 | 0.0240072 |
| CANX | calnexin | 0.023868 |
| JAK1 | Janus kinase 1 | 0.0238669 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0232626 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0232458 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0228224 |
| FN1 | fibronectin 1 | 0.0225309 |
| HELZ | helicase with zinc finger | 0.0225195 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0224757 |
| XPO1 | exportin 1 | 0.0222812 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.0222424 |
| ANKRD11 | ankyrin repeat domain 11 | 0.022075 |
| COPA | coatomer protein complex, subunit alpha | 0.0220466 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0211448 |
| GSE1 | Gse1 coiled-coil protein | 0.0209469 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0209158 |
| DSTN | destrin (actin depolymerizing factor) | 0.0208452 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0206767 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0205241 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0205132 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0201376 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0201114 |
| PER1 | period circadian clock 1 | 0.0200532 |
| PCM1 | pericentriolar material 1 | 0.0199767 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0198291 |
| RYBP | RING1 and YY1 binding protein | 0.0195925 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0195096 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0194599 |
| NEFL | neurofilament, light polypeptide | 0.0189442 |
| HDLBP | high density lipoprotein binding protein | 0.0189306 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.0184642 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0184576 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0183566 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0182263 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0181618 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0179491 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0178216 |
| MEF2A | myocyte enhancer factor 2A | 0.0177505 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0175305 |
| ITGAV | integrin, alpha V | 0.0174909 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0174653 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0174547 |
| RNF24 | ring finger protein 24 | 0.0173999 |
| TNS3 | tensin 3 | 0.0171705 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0171026 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.319208 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.217512 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.19383 |
| PODXL | podocalyxin-like | -0.185379 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.150376 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.14675 |
| NAV1 | neuron navigator 1 | -0.1403 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0804 |
| TMSB10 | thymosin beta 10 | -0.0775634 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0771207 |
| CD44 | CD44 molecule (Indian blood group) | -0.0770594 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0756981 |
| PLAT | plasminogen activator, tissue | -0.072148 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.069501 |
| VIM | vimentin | -0.068192 |
| EGFR | epidermal growth factor receptor | -0.057479 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0573291 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0569337 |
| SUCNR1 | succinate receptor 1 | -0.0549867 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.05419 |
| MX2 | MX dynamin-like GTPase 2 | -0.0528754 |
| NDRG1 | N-myc downstream regulated 1 | -0.0526792 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0516608 |
| MYADM | myeloid-associated differentiation marker | -0.0515961 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0498337 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0490811 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0476751 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0475367 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0462121 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.045488 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0442331 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0418628 |
| EHBP1 | EH domain binding protein 1 | -0.0409839 |
| FLNB | filamin B, beta | -0.0402026 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.039987 |
| THBS2 | thrombospondin 2 | -0.0388328 |
| COL5A1 | collagen, type V, alpha 1 | -0.0385446 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0381682 |
| FRMD5 | FERM domain containing 5 | -0.037925 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0360564 |
| SP3 | Sp3 transcription factor | -0.0349778 |
| PRSS23 | protease, serine, 23 | -0.0343575 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0340337 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0335221 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0322394 |
| RUNX1 | runt-related transcription factor 1 | -0.0321617 |
| FRMD4A | FERM domain containing 4A | -0.0321402 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0318301 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0316229 |
| HDAC9 | histone deacetylase 9 | -0.0315841 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0309036 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0301853 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0294995 |
| ASPH | aspartate beta-hydroxylase | -0.0293368 |
| RNF213 | ring finger protein 213 | -0.0292603 |
| CDH13 | cadherin 13 | -0.029191 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0291683 |
| KIFAP3 | kinesin-associated protein 3 | -0.0287343 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0286117 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.026323 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0260405 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.025461 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0254538 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | -0.0248757 |
| CCND1 | cyclin D1 | -0.0247273 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0240017 |
| TPM1 | tropomyosin 1 (alpha) | -0.0237227 |
| MYO9B | myosin IXB | -0.0235426 |
| E2F7 | E2F transcription factor 7 | -0.0232542 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0228968 |
| GLIS3 | GLIS family zinc finger 3 | -0.0227085 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0223242 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0216163 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0216133 |
| TAGLN2 | transgelin 2 | -0.0213305 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0212511 |
| COL1A2 | collagen, type I, alpha 2 | -0.0205618 |
| CMIP | c-Maf inducing protein | -0.0203058 |
| VEGFC | vascular endothelial growth factor C | -0.0202891 |
| SEPTIN9 | septin 9 | -0.0200125 |
| HLA-B | major histocompatibility complex, class I, B | -0.019984 |
| PLAUR | plasminogen activator, urokinase receptor | -0.019834 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0197932 |
| KIAA1217 | KIAA1217 | -0.0196251 |
| TAPBP | TAP binding protein (tapasin) | -0.0195331 |
| MAP1B | microtubule-associated protein 1B | -0.0193453 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0192415 |
| TOX | thymocyte selection-associated high mobility group box | -0.0192134 |
| POTEF | POTE ankyrin domain family, member F | -0.0191732 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0188969 |
| AFDN | afadin, adherens junction formation factor | -0.0186858 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0186623 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0186185 |
| ZNF217 | zinc finger protein 217 | -0.0185791 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0185787 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0184929 |
| SAA2 | serum amyloid A2 | -0.0183764 |
| RSF1 | remodeling and spacing factor 1 | -0.0183199 |
| NEK7 | NIMA-related kinase 7 | -0.0182202 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0179068 |
