| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clobetasol propionate perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clobetasol propionate_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.0603071 |
| LMO7 | LIM domain 7 | 0.0572069 |
| TMEM41B | transmembrane protein 41B | 0.0489032 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0468453 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0414371 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0388384 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0386747 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0361997 |
| KIF5B | kinesin family member 5B | 0.0319563 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0316788 |
| OXR1 | oxidation resistance 1 | 0.0305589 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0273758 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0271974 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0263014 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0222855 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0203557 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0187175 |
| IL6ST | interleukin 6 signal transducer | 0.0184972 |
| GCG | glucagon | 0.0181883 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0177525 |
| RTN4 | reticulon 4 | 0.0176947 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0176203 |
| CEP95 | centrosomal protein 95kDa | 0.0174706 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0169505 |
| TMEM131 | transmembrane protein 131 | 0.0167627 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0161719 |
| ETNK1 | ethanolamine kinase 1 | 0.0159619 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0159167 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0158804 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.0157886 |
| KLF6 | Kruppel-like factor 6 | 0.0157227 |
| RPLP0 | ribosomal protein, large, P0 | 0.0150981 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0147589 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.0147497 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0144423 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0143012 |
| PEG10 | paternally expressed 10 | 0.0140551 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0139306 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0139275 |
| TJP1 | tight junction protein 1 | 0.013861 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0136985 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0135954 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0133672 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0129375 |
| ATXN3 | ataxin 3 | 0.0129097 |
| TNPO1 | transportin 1 | 0.0128171 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0127877 |
| CEP70 | centrosomal protein 70kDa | 0.0127681 |
| NEGR1 | neuronal growth regulator 1 | 0.0127396 |
| FAM169A | family with sequence similarity 169, member A | 0.0126453 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0123257 |
| YTHDC2 | YTH domain containing 2 | 0.0123135 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0121977 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0120496 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0119528 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.0119407 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0117331 |
| EDN1 | endothelin 1 | 0.0117157 |
| PARD6B | par-6 family cell polarity regulator beta | 0.0117066 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0115935 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0115499 |
| RETREG1 | reticulophagy regulator 1 | 0.0114065 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0114039 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.011323 |
| ATP11B | ATPase, class VI, type 11B | 0.0113034 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0112255 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | 0.0111681 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0111589 |
| THOC1 | THO complex 1 | 0.0110839 |
| LEKR1 | leucine, glutamate and lysine rich 1 | 0.011075 |
| NEK7 | NIMA-related kinase 7 | 0.0110444 |
| SLC49A4 | solute carrier family 49 member 4 | 0.0109159 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0108567 |
| PDCD10 | programmed cell death 10 | 0.010789 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0107839 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 0.010686 |
| MEAF6 | MYST/Esa1-associated factor 6 | 0.0106762 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0106201 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0106041 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0104275 |
| CCNG1 | cyclin G1 | 0.010344 |
| RNF145 | ring finger protein 145 | 0.0102961 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0101405 |
| MAGEA4 | melanoma antigen family A4 | 0.0101325 |
| TUBB6 | tubulin, beta 6 class V | 0.0101233 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.0100861 |
| CNOT9 | CCR4-NOT transcription complex subunit 9 | 0.0100563 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0100108 |
| USP24 | ubiquitin specific peptidase 24 | 0.00999211 |
| URI1 | URI1, prefoldin-like chaperone | 0.00995998 |
| MEIOC | meiosis specific with coiled-coil domain | 0.00986093 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.00978725 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.00977251 |
| ETV1 | ets variant 1 | 0.00971877 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.00964257 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | 0.00957473 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | 0.00953681 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.00950889 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00945362 |
| OSMR | oncostatin M receptor | 0.00943196 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.208572 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.193704 |
| VIM | vimentin | -0.126347 |
| NLGN1 | neuroligin 1 | -0.116407 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.112267 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.109209 |
| HMGA2 | high mobility group AT-hook 2 | -0.103984 |
| TMSB10 | thymosin beta 10 | -0.103833 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0943598 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0911819 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0895331 |
| ACTG1 | actin gamma 1 | -0.0881533 |
| RPS27A | ribosomal protein S27a | -0.084247 |
| UBC | ubiquitin C | -0.0799356 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0771178 |
| EHBP1 | EH domain binding protein 1 | -0.0760427 |
| PTMA | prothymosin, alpha | -0.0734175 |
| ASPH | aspartate beta-hydroxylase | -0.0719778 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0661943 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0655453 |
| RRM2 | ribonucleotide reductase M2 | -0.0648618 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0646102 |
| ENO1 | enolase 1, (alpha) | -0.063884 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0629501 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0626997 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0620711 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0614822 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0604238 |
| PCBP2 | poly(rC) binding protein 2 | -0.0602857 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0602767 |
| AHNAK | AHNAK nucleoprotein | -0.057382 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0556886 |
| RPL23 | ribosomal protein L23 | -0.0540682 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0530398 |
| YAP1 | Yes-associated protein 1 | -0.0519106 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0512819 |
| ADIPOR2 | adiponectin receptor 2 | -0.0508746 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0498566 |
| NEBL | nebulette | -0.0493992 |
| INTS6 | integrator complex subunit 6 | -0.0493773 |
| VMP1 | vacuole membrane protein 1 | -0.0479714 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.047575 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0474138 |
| FTL | ferritin, light polypeptide | -0.0473601 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0464754 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0464381 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0454206 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0450615 |
| PCDH7 | protocadherin 7 | -0.0441417 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0430058 |
| IPO7 | importin 7 | -0.0418483 |
| RPS12 | ribosomal protein S12 | -0.0414712 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0412974 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0410319 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0408582 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0405405 |
| TPM3 | tropomyosin 3 | -0.0404097 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0402992 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0400049 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0396574 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0392774 |
| TPI1 | triosephosphate isomerase 1 | -0.0389162 |
| SET | SET nuclear proto-oncogene | -0.0377334 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0368423 |
| DENND5A | DENN/MADD domain containing 5A | -0.036828 |
| LDHA | lactate dehydrogenase A | -0.0360266 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0360183 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.035967 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0352859 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.034691 |
| RASAL2 | RAS protein activator like 2 | -0.0346415 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.034478 |
| ZNF292 | zinc finger protein 292 | -0.0342395 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0339587 |
| GNAS | GNAS complex locus | -0.0339421 |
| USP34 | ubiquitin specific peptidase 34 | -0.0338895 |
| MMP12 | matrix metallopeptidase 12 | -0.0333965 |
| MTAP | methylthioadenosine phosphorylase | -0.0333485 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0331891 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0325875 |
| CMIP | c-Maf inducing protein | -0.0325835 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0318991 |
| RPS8 | ribosomal protein S8 | -0.0317295 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0312329 |
| PRELID2 | PRELI domain containing 2 | -0.0311225 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0309145 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0306339 |
| BCHE | butyrylcholinesterase | -0.0302011 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0301403 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0300593 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0297986 |
| HDGF | hepatoma-derived growth factor | -0.0297538 |
| MED13 | mediator complex subunit 13 | -0.0297059 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0294409 |
| YBX1 | Y box binding protein 1 | -0.0293658 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0286633 |
| CLDN1 | claudin 1 | -0.0286042 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0285308 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0281053 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0280197 |
